> Serine palmitoyltransferase, long chain base subunit 3 (SPTLC3)
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UGID:225380     UniGene Hs.425023     Homo sapiens (human)   SPTLC3 Order cDNA clone, Links
Serine palmitoyltransferase, long chain base subunit 3 (SPTLC3)

Human protein-coding gene SPTLC3. Represented by 116 ESTs from 64 cDNA libraries. Corresponds to reference sequence NM_018327.2. [UniGene 225380 - Hs.425023]

SELECTED PROTEIN SIMILARITIES
Comparison of cluster transcripts with RefSeq proteins. The alignments can suggest function of the cluster.
Best Hits and Hits from model organismsSpeciesId(%)Len(aa)
XP_001135152.1 PREDICTED: serine palmitoyltransferase 3 isoform 3 P. troglodytes 100.0 551
NP_060797.2 SPTLC3 gene product H. sapiens 100.0 551
NP_001089928.1 serine palmitoyltransferase, long chain base subunit 3 X. laevis 80.4 541
NP_001003562.1 sptlc3 gene product D. rerio 76.8 552
NP_780676.1 Sptlc3 gene product M. musculus 76.0 551
NP_505065.1 Protein SPTL-2, isoform a C. elegans 60.3 489
NP_476614.1 lace D. melanogaster 58.5 483
XP_956766.1 serine palmitoyltransferase 2 N. crassa 57.0 475
NP_190447.1 serine palmitoyltransferase 1 A. thaliana 56.1 467
XP_001692248.1 component of serine palmitoyltransferase C. reinhardtii 55.3 424
NP_010347.1 serine C-palmitoyltransferase LCB2 S. cerevisiae 53.6 476
Other hits (2 of 58) [Show all]SpeciesId(%)Len(aa)
XP_003905129.1 PREDICTED: serine palmitoyltransferase 3 P. anubis 98.7 551
XP_001082737.2 PREDICTED: serine palmitoyltransferase 3-like isoform 3 M. mulatta 97.1 549

GENE EXPRESSION
Tissues and development stages from this gene's sequences survey gene expression. Links to other NCBI expression resources.
EST Profile: Approximate expression patterns inferred from EST sources.
[Show more entries with profiles like this]
GEO Profiles: Experimental gene expression data (Gene Expression Omnibus).
cDNA Sources: placenta; uncharacterized tissue; mixed; skin; ear; mammary gland; stomach; bladder; embryonic tissue; eye; thyroid; brain; lung; ovary; kidney; pharynx; uterus; esophagus; parathyroid; ascites; bone; cervix; liver; prostate; intestine
MAPPING POSITION
Genomic location specified by transcript mapping, radiation hybrid mapping, genetic mapping or cytogenetic mapping.
Chromosome: 20
Map position: 20p12.1
UniSTS entry: Chr 20 A006P19 [Map Viewer]
UniSTS entry: Chr 20 SHGC-33870 [Map Viewer]
UniSTS entry: Chr 20 RH48472 [Map Viewer]
UniSTS entry: Chr 20 D20S58
UniSTS entry: Chr 1 G27414
SEQUENCES
Sequences representing this gene; mRNAs, ESTs, and gene predictions supported by transcribed sequences.

mRNA sequences (8)

AK001974.1 Homo sapiens cDNA FLJ11112 fis, clone PLACE1005925 P
NM_018327.2 Homo sapiens serine palmitoyltransferase, long chain base subunit 3 (SPTLC3), mRNA PA
BC020656.1 Homo sapiens serine palmitoyltransferase, long chain base subunit 3, mRNA (cDNA clone IMAGE:4770239), complete cds PA
AK300184.1 Homo sapiens cDNA FLJ52240 complete cds, moderately similar to Serine palmitoyltransferase 2 (EC 2.3.1.50) P
AK075271.1 Homo sapiens cDNA FLJ90790 fis, clone THYRO1001529, moderately similar to Serine palmitoyltransferase 2 (EC 2.3.1.50) P
BC005205.1 Homo sapiens serine palmitoyltransferase, long chain base subunit 3, mRNA (cDNA clone IMAGE:3961439), partial cds PA
BC150644.1 Homo sapiens serine palmitoyltransferase, long chain base subunit 3, mRNA (cDNA clone MGC:183554 IMAGE:9057014), complete cds P
BC038248.1 Homo sapiens serine palmitoyltransferase, long chain base subunit 3, mRNA (cDNA clone IMAGE:4525999), with apparent retained intron PA

EST sequences (10 of 116) [Show all sequences]

CB054740.1 Clone IMAGE:3291533 brain 5' read
BX108952.1 Clone IMAGp998K05560_;_IMAGE:257404 placenta
R27954.1 Clone IMAGE:133808 placenta 3' read A
R28201.1 Clone IMAGE:133808 placenta 5' read
CB114394.1 Clone L8SCK0-1-C10 liver 5' read
AI288996.1 Clone IMAGE:1879256 mixed 3' read A
AI375409.1 Clone IMAGE:2043441 brain 3' read A
AI610283.1 Clone IMAGE:2187789 stomach 3' read A
AI744812.1 Clone IMAGE:2218386 ovary 3' read A
AL037465.2 Clone DKFZp564B2272 brain 5' read


Key to Symbols

P Has similarity to known Proteins (after translation)
A Contains a poly-Adenylation signal
S Sequence is a Suboptimal member of this cluster
M Clone is putatively CDS-complete by MGC criteria

 
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