Coagulation factor II (thrombin) receptor-like 2 (F2RL2)

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UGID:136948 UniGene Hs.42502 Homo sapiens (human) F2RL2

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Coagulation factor II (thrombin) receptor-like 2 (F2RL2)

Human protein-coding gene F2RL2. Represented by 88 ESTs from 43 cDNA libraries. Corresponds to 2 reference sequences (different isoforms). [UniGene 136948 - Hs.42502]

SELECTED PROTEIN SIMILARITIES

Comparison of cluster transcripts with RefSeq proteins. The alignments can suggest function of the cluster.

Best Hits and Hits from model organisms		Species	Id(%)	Len(aa)
XP_003310722.1 Conserved domains (CDD) Gene summary Protein sequence Protein/EST matches (ProtEST) Protein/protein matches (BLink)	PREDICTED: proteinase-activated receptor 3	P. troglodytes	100.0	373
NP_004092.1 Conserved domains (CDD) Gene summary Protein sequence Protein/EST matches (ProtEST) Protein/protein matches (BLink)	F2RL2 gene product	H. sapiens	100.0	373
NP_034300.3 Conserved domains (CDD) Gene summary Protein sequence Protein/EST matches (ProtEST) Protein/protein matches (BLink)	F2rl2 gene product	M. musculus	74.9	362
NP_001079539.1 Conserved domains (CDD) Gene summary Protein sequence Protein/EST matches (ProtEST) Protein/protein matches (BLink)	coagulation factor II (thrombin) receptor-like 2 precursor	X. laevis	53.1	373
XP_002665915.1 Conserved domains (CDD) Gene summary Protein sequence Protein/EST matches (ProtEST) Protein/protein matches (BLink)	PREDICTED: proteinase-activated receptor 3-like	D. rerio	46.2	184
Other hits (2 of 14) [Show all]		Species	Id(%)	Len(aa)
XP_001106069.1 Conserved domains (CDD) Gene summary Protein sequence Protein/EST matches (ProtEST) Protein/protein matches (BLink)	PREDICTED: proteinase-activated receptor 3 isoform 1	M. mulatta	98.7	373
XP_003899881.1 Conserved domains (CDD) Gene summary Protein sequence Protein/EST matches (ProtEST) Protein/protein matches (BLink)	PREDICTED: proteinase-activated receptor 3	P. anubis	98.7	373

GENE EXPRESSION

Tissues and development stages from this gene's sequences survey gene expression. Links to other NCBI expression resources.

	EST Profile:	Approximate expression patterns inferred from EST sources. [Show more entries with profiles like this]
	GEO Profiles:	Experimental gene expression data (Gene Expression Omnibus).
	cDNA Sources:	kidney; skin; mixed; muscle; pancreas; brain; uncharacterized tissue; mammary gland; mouth; vascular; connective tissue; testis; thymus; trachea; embryonic tissue; lung; thyroid; heart; bone; stomach; nerve

MAPPING POSITION

Genomic location specified by transcript mapping, radiation hybrid mapping, genetic mapping or cytogenetic mapping.

Chromosome:	5
Map position:	5q13
UniSTS entry:	Chr 5	STS-N26732	[Map Viewer]
UniSTS entry:	Chr 1	D11S3114
UniSTS entry:	Chr 5	F2RL2_622

SEQUENCES

Sequences representing this gene; mRNAs, ESTs, and gene predictions supported by transcribed sequences.

mRNA sequences (9)

BX537386.1	Homo sapiens mRNA; cDNA DKFZp686N1782 (from clone DKFZp686N1782); complete cds	PA
NM_004101.3	Homo sapiens coagulation factor II (thrombin) receptor-like 2 (F2RL2), transcript variant 1, mRNA	PA
BC093650.1	Homo sapiens coagulation factor II (thrombin) receptor-like 2, mRNA (cDNA clone MGC:120685 IMAGE:7939495), complete cds	P
BC093648.1	Homo sapiens coagulation factor II (thrombin) receptor-like 2, mRNA (cDNA clone MGC:120683 IMAGE:7939493), complete cds	P
BC095499.1	Homo sapiens coagulation factor II (thrombin) receptor-like 2, mRNA (cDNA clone IMAGE:7002018), partial cds	P
AK312848.1	Homo sapiens cDNA, FLJ93290, Homo sapiens coagulation factor II (thrombin) receptor-like 2 (F2RL2), mRNA	P
AK298585.1	Homo sapiens cDNA FLJ51933 complete cds, highly similar to Proteinase-activated receptor 3 precursor	P
NM_001256566.1	Homo sapiens coagulation factor II (thrombin) receptor-like 2 (F2RL2), transcript variant 2, mRNA	PA
U92971.1	Human protease-activated receptor 3 (PAR3) mRNA, complete cds	P

EST sequences (10 of 88) [Show all sequences]

AA983803.1	Clone IMAGE:1580959	mixed	3' read
AI041793.1	Clone IMAGE:1665418	skin	3' read	A
AI131231.1	Clone IMAGE:1709756	heart	3' read	A
AI270217.1	Clone IMAGE:1978636	stomach	3' read	A
AI279473.1	Clone IMAGE:1882361	lung	3' read	A
AI378647.1	Clone IMAGE:2068686	mixed	3' read	A
AL048674.3	Clone DKFZp566B043	kidney		A
AL048675.2	Clone DKFZp566B043	kidney		A
BX474658.1	Clone DKFZp686G04171	muscle	5' read	P
CF126741.1	Clone IMAGE:30560278	lung	5' read

Key to Symbols

P Has similarity to known Proteins (after translation)
A Contains a poly-Adenylation signal
S Sequence is a Suboptimal member of this cluster
M Clone is putatively CDS-complete by MGC criteria