> Histamine N-methyltransferase (HNMT)
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UGID:136896     UniGene Hs.42151     Homo sapiens (human)   HNMT Order cDNA clone, Links
Histamine N-methyltransferase (HNMT)

Human protein-coding gene HNMT. Represented by 251 ESTs from 116 cDNA libraries. Corresponds to 3 reference sequences (different isoforms). [UniGene 136896 - Hs.42151]

SELECTED PROTEIN SIMILARITIES
Comparison of cluster transcripts with RefSeq proteins. The alignments can suggest function of the cluster.
Best Hits and Hits from model organismsSpeciesId(%)Len(aa)
NP_008826.1 HNMT gene product H. sapiens 100.0 291
NP_536710.1 Hnmt gene product M. musculus 86.0 293
NP_001080614.1 histamine N-methyltransferase B X. laevis 63.4 292
NP_001003636.1 hnmt gene product D. rerio 47.7 262
Other hits (2 of 22) [Show all]SpeciesId(%)Len(aa)
XP_001155975.1 PREDICTED: histamine N-methyltransferase isoform 1 P. troglodytes 99.3 291
XP_001094746.1 PREDICTED: histamine N-methyltransferase M. mulatta 95.2 291

GENE EXPRESSION
Tissues and development stages from this gene's sequences survey gene expression. Links to other NCBI expression resources.
EST Profile: Approximate expression patterns inferred from EST sources.
[Show more entries with profiles like this]
GEO Profiles: Experimental gene expression data (Gene Expression Omnibus).
cDNA Sources: mixed; kidney; liver; uncharacterized tissue; brain; placenta; lymph node; intestine; uterus; eye; testis; vascular; umbilical cord; bladder; lung; pharynx; muscle; connective tissue; spinal cord; heart; esophagus; trachea; skin; pancreas; embryonic tissue; mammary gland; stomach; prostate; adrenal gland; blood; ovary; parathyroid; bone marrow
MAPPING POSITION
Genomic location specified by transcript mapping, radiation hybrid mapping, genetic mapping or cytogenetic mapping.
Chromosome: 2
Map position: 2q22.1
UniSTS entry: Chr 2 RH80835
UniSTS entry: Chr 2 STS-AA036662
UniSTS entry: Chr 2 RH68885
SEQUENCES
Sequences representing this gene; mRNAs, ESTs, and gene predictions supported by transcribed sequences.

mRNA sequences (14)

NM_006895.2 Homo sapiens histamine N-methyltransferase (HNMT), transcript variant 1, mRNA PA
NM_001024075.1 Homo sapiens histamine N-methyltransferase (HNMT), transcript variant 3, mRNA
NM_001024074.2 Homo sapiens histamine N-methyltransferase (HNMT), transcript variant 2, mRNA A
D16224.1 Homo sapiens mRNA for histamine N-methyltransferase, complete cds P
BC005907.1 Homo sapiens histamine N-methyltransferase, mRNA (cDNA clone IMAGE:4249496), complete cds A
U08092.1 Human histamine N-methyltransferase (HNMT) mRNA, complete cds P
BC020677.1 Homo sapiens histamine N-methyltransferase, mRNA (cDNA clone MGC:22386 IMAGE:4767331), complete cds PA
AK313804.1 Homo sapiens cDNA, FLJ94422, Homo sapiens histamine N-methyltransferase (HNMT), mRNA P
AK301462.1 Homo sapiens cDNA FLJ51345 complete cds, highly similar to Histamine N-methyltransferase (EC 2.1.1.8) P
AF523360.1 Homo sapiens histamine N-methyltransferase variant 3 (HNMT) mRNA, complete cds; alternatively spliced P
AF523359.1 Homo sapiens histamine N-methyltransferase variant 2 (HNMT) mRNA, complete cds; alternatively spliced P
AF523358.1 Homo sapiens histamine N-methyltransferase variant 1 (HNMT) mRNA, complete cds; alternatively spliced P
AF523357.1 Homo sapiens histamine N-methyltransferase short variant 2 (HNMT) mRNA, complete cds; alternatively spliced
AF523356.1 Homo sapiens histamine N-methyltransferase short variant 1 (HNMT) mRNA, complete cds; alternatively spliced

EST sequences (10 of 251) [Show all sequences]

AA970552.1 Clone IMAGE:1573890 kidney 3' read
R17186.1 Clone IMAGE:31925 brain 5' read
AA928181.1 Clone IMAGE:1541432 mixed 3' read
AI040233.1 Clone IMAGE:1660331 mixed 3' read
AI041483.1 Clone IMAGE:1648196 parathyroid 3' read
AI097234.1 Clone IMAGE:1704458 brain 3' read
CB052644.1 Clone IMAGE:3290488 uncharacterized tissue 3' read A
CB052645.1 Clone IMAGE:3290488 uncharacterized tissue 5' read
BX094953.1 Clone IMAGp998A2290_;_IMAGE:112413 mixed P
BX102705.1 Clone IMAGp998N125472_;_IMAGE:2213195 uterus A


Key to Symbols

P Has similarity to known Proteins (after translation)
A Contains a poly-Adenylation signal
S Sequence is a Suboptimal member of this cluster
M Clone is putatively CDS-complete by MGC criteria

 
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