> Glutamate decarboxylase 1 (brain, 67kDa) (GAD1)
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UGID:224102     UniGene Hs.420036     Homo sapiens (human)   GAD1 Order cDNA clone, Links
Glutamate decarboxylase 1 (brain, 67kDa) (GAD1)

Human protein-coding gene GAD1. Represented by 779 ESTs from 97 cDNA libraries. Corresponds to 2 reference sequences (different isoforms). [UniGene 224102 - Hs.420036]

SELECTED PROTEIN SIMILARITIES
Comparison of cluster transcripts with RefSeq proteins. The alignments can suggest function of the cluster.
Best Hits and Hits from model organismsSpeciesId(%)Len(aa)
NP_000808.2 GAD1 gene product H. sapiens 100.0 593
XP_001082995.1 PREDICTED: glutamate decarboxylase 1 isoform 1 M. mulatta 99.8 593
XP_003907639.1 PREDICTED: glutamate decarboxylase 1 P. anubis 99.8 593
NP_001029285.1 GAD1 gene product P. troglodytes 99.8 593
NP_032103.2 Gad1 gene product M. musculus 98.8 592
NP_919400.1 gad1b gene product D. rerio 90.0 586
NP_001079270.1 glutamate decarboxylase 1 X. laevis 86.6 544
NP_523914.2 glutamic acid decarboxylase 1, isoform A D. melanogaster 64.4 493
NP_499689.1 Protein UNC-25, isoform a C. elegans 62.7 493
Other hits (2 of 37) [Show all]SpeciesId(%)Len(aa)
NP_001091012.1 GAD1 gene product C. lupus familiaris 99.2 593
XP_001498306.1 PREDICTED: glutamate decarboxylase 1-like isoform 1 E. caballus 99.0 593

GENE EXPRESSION
Tissues and development stages from this gene's sequences survey gene expression. Links to other NCBI expression resources.
EST Profile: Approximate expression patterns inferred from EST sources.
[Show more entries with profiles like this]
GEO Profiles: Experimental gene expression data (Gene Expression Omnibus).
cDNA Sources: brain; mammary gland; intestine; placenta; kidney; testis; mixed; larynx; eye; uncharacterized tissue; muscle; thymus; liver; embryonic tissue; uterus; ovary; bone; parathyroid; trachea
MAPPING POSITION
Genomic location specified by transcript mapping, radiation hybrid mapping, genetic mapping or cytogenetic mapping.
Chromosome: 2
Map position: 2q31
UniSTS entry: Chr 2 SHGC-30155 [Map Viewer]
UniSTS entry: Chr 2 SHGC-31511 [Map Viewer]
UniSTS entry: Chr 2 GAD1
UniSTS entry: Chr 2 G66912
UniSTS entry: Chr 17 SHGC-30137 [Map Viewer]
SEQUENCES
Sequences representing this gene; mRNAs, ESTs, and gene predictions supported by transcribed sequences.

mRNA sequences (19)

AK127781.1 Homo sapiens cDNA FLJ45882 fis, clone OCBBF3020674, highly similar to Glutamate decarboxylase, 67 kDa isoform (EC 4.1.1.15) P
AK123534.1 Homo sapiens cDNA FLJ41540 fis, clone BRTHA2019022
NM_000817.2 Homo sapiens glutamate decarboxylase 1 (brain, 67kDa) (GAD1), transcript variant GAD67, mRNA PA
AF178853.2 Homo sapiens glutamic acid decarboxylase GAD25 (GAD67) mRNA, complete cds PA
NM_013445.3 Homo sapiens glutamate decarboxylase 1 (brain, 67kDa) (GAD1), transcript variant GAD25, mRNA PA
L16888.1 Human glutamate decarboxylase (GAD67) mRNA, complete cds PA
BC002815.2 Homo sapiens glutamate decarboxylase 1 (brain, 67kDa), mRNA (cDNA clone IMAGE:3659686), complete cds PA
M81883.1 Human glutamate decarboxylase (GAD67) mRNA, complete cds PA
AK292582.1 Homo sapiens cDNA FLJ77623 complete cds, highly similar to Homo sapiens glutamate decarboxylase 1 (brain, 67kDa) (GAD1), transcript variant GAD67, mRNA P
AK307460.1 Homo sapiens cDNA, FLJ97408 P
BC026349.1 Homo sapiens glutamate decarboxylase 1 (brain, 67kDa), mRNA (cDNA clone MGC:26799 IMAGE:4794214), complete cds PA
Z22750.1 H.sapiens GAD67 mRNA for glutamate decarboxylase PA
M70435.1 Human pancreatic islet glutamic acid decarboxylase (GAD) mRNA, partial cds P
M70434.1 Human brain glutamic acid decarboxylase (GAD) mRNA, partial cds P
BC037780.2 Homo sapiens glutamate decarboxylase 1 (brain, 67kDa), mRNA (cDNA clone MGC:41888 IMAGE:5273792), complete cds PA
S61897.1 glutamic acid decarboxylase 67 kda form [human, pancreas, mRNA, 1824 nt] P
S61898.1 glutamic acid decarboxylase 67 kda isoform [human, pancreatic islet, mRNA, 2298 nt] P
BC036552.1 Homo sapiens glutamate decarboxylase 1 (brain, 67kDa), mRNA (cDNA clone MGC:43269 IMAGE:5264831), complete cds PA
M55574.1 Human glutamic acid decarboxylase (GAD) mRNA, 3'end

EST sequences (10 of 779) [Show all sequences]

AI028188.1 Clone IMAGE:1644588 testis 3' read PA
AI087804.1 Clone IMAGE:1566727 mixed 3' read A
BX090384.1 Clone IMAGp998C04618_;_IMAGE:279483 brain
CB125393.1 Clone L5HLK1s1-13-F09 liver 5' read
CB156303.1 Clone B2N807043-15-D11 brain 5' read P
CB143048.1 Clone L15CKK1-21-C01 liver 5' read
AI306437.1 Clone IMAGE:1900219 kidney 3' read PA
AI362721.1 Clone IMAGE:2017367 brain 3' read A
AI391572.1 Clone IMAGE:2108930 uncharacterized tissue 3' read PA
AI459724.1 Clone IMAGE:1955564 brain 3' read


Key to Symbols

P Has similarity to known Proteins (after translation)
A Contains a poly-Adenylation signal
S Sequence is a Suboptimal member of this cluster
M Clone is putatively CDS-complete by MGC criteria

 
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