Distal-less homeobox 2 (DLX2)

Restricted Expression:

embryoid body [show more like this]

EST Profile:

Approximate expression patterns inferred from EST sources.
[Show more entries with profiles like this]

GEO Profiles:

Experimental gene expression data (Gene Expression Omnibus).

cDNA Sources:

brain; embryonic tissue; lung; blood; pancreas; ovary; intestine; mixed; mouth; stomach; thyroid; pharynx

NCBI

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Finding cDNAs

UGID:130756 UniGene Hs.419 Homo sapiens (human) DLX2

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Distal-less homeobox 2 (DLX2)

Human protein-coding gene DLX2. Represented by 37 ESTs from 22 cDNA libraries. EST representation biased toward embryoid body. Corresponds to reference sequence NM_004405.3. [UniGene 130756 - Hs.419]

SELECTED PROTEIN SIMILARITIES

Comparison of cluster transcripts with RefSeq proteins. The alignments can suggest function of the cluster.

Best Hits and Hits from model organisms		Species	Id(%)	Len(aa)
NP_004396.1 Conserved domains (CDD) Gene summary Protein sequence Protein/EST matches (ProtEST) Protein/protein matches (BLink)	DLX2 gene product	H. sapiens	100.0	327
NP_034184.1 Conserved domains (CDD) Gene summary Protein sequence Protein/EST matches (ProtEST) Protein/protein matches (BLink)	Dlx2 gene product	M. musculus	94.6	331
NP_001084032.1 Conserved domains (CDD) Gene summary Protein sequence Protein/EST matches (ProtEST) Protein/protein matches (BLink)	homeobox protein DLL-4	X. laevis	72.6	284
NP_571386.1 Conserved domains (CDD) Gene summary Protein sequence Protein/EST matches (ProtEST) Protein/protein matches (BLink)	dlx2a gene product	D. rerio	68.2	269
Other hits (2 of 20) [Show all]		Species	Id(%)	Len(aa)
XP_001086012.1 Conserved domains (CDD) Gene summary Protein sequence Protein/EST matches (ProtEST) Protein/protein matches (BLink)	PREDICTED: homeobox protein DLX-2	M. mulatta	98.5	327
XP_003907661.1 Conserved domains (CDD) Gene summary Protein sequence Protein/EST matches (ProtEST) Protein/protein matches (BLink)	PREDICTED: homeobox protein DLX-2	P. anubis	98.5	327

GENE EXPRESSION

Tissues and development stages from this gene's sequences survey gene expression. Links to other NCBI expression resources.

MAPPING POSITION

Genomic location specified by transcript mapping, radiation hybrid mapping, genetic mapping or cytogenetic mapping.

Chromosome:	2
Map position:	2q32
UniSTS entry:	Chr 2	RH68996	[Map Viewer]

SEQUENCES

Sequences representing this gene; mRNAs, ESTs, and gene predictions supported by transcribed sequences.

mRNA sequences (7)

NM_004405.3	Homo sapiens distal-less homeobox 2 (DLX2), mRNA	P
AB208823.1	Homo sapiens mRNA for distal-less homeo box 2 variant protein	P
AK291367.1	Homo sapiens cDNA FLJ75693 complete cds, highly similar to Homo sapiens distal-less homeo box 2 (DLX2), mRNA	P
BC032558.1	Homo sapiens distal-less homeobox 2, mRNA (cDNA clone MGC:45154 IMAGE:5562689), complete cds	PA
AK297503.1	Homo sapiens cDNA FLJ56718 complete cds, highly similar to Homeobox protein DLX-2	P
AK316129.1	Homo sapiens cDNA, FLJ79028 complete cds, highly similar to Homeobox protein DLX-2	P
L07919.1	Human homeodomain protein DLX-2 mRNA, 3' end	P

EST sequences (10 of 37) [Show all sequences]

BX283905.1	Clone IMAGp958O10784_;_IMAGE:3938145	lung		P
BX341351.2	Clone CS0DJ015YE17	blood	5' read	P
BX369487.1	Clone CS0DJ015YE17	blood	5' read	P
BX393177.2	Clone CS0DJ015YE17	blood	3' read
BX412950.2	Clone CS0DF012YH22	brain	3' read
BX434867.2	Clone CS0DF012YH20	brain	3' read
BX442871.1	Clone CS0DF038YJ20	brain	3' read
BX442872.2	Clone CS0DF038YJ20	brain	5' read	P
BX460303.2	Clone CS0DF012YH20	brain	5' read
CN282827.1		embryonic tissue	5' read	P

Key to Symbols

P Has similarity to known Proteins (after translation)
A Contains a poly-Adenylation signal
S Sequence is a Suboptimal member of this cluster
M Clone is putatively CDS-complete by MGC criteria