> S100 calcium binding protein A8 (S100A8)
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UGID:222934     UniGene Hs.416073     Homo sapiens (human)   S100A8 Order cDNA clone, Links
S100 calcium binding protein A8 (S100A8)

Human protein-coding gene S100A8. Represented by 512 ESTs from 124 cDNA libraries. EST representation biased toward adult. Corresponds to reference sequence NM_002964.4. [UniGene 222934 - Hs.416073]

SELECTED PROTEIN SIMILARITIES
Comparison of cluster transcripts with RefSeq proteins. The alignments can suggest function of the cluster.
Best Hits and Hits from model organismsSpeciesId(%)Len(aa)
XP_513814.2 PREDICTED: protein S100-A8 isoform 8 P. troglodytes 100.0 92
NP_002955.2 S100A8 gene product H. sapiens 100.0 92
Other hits (2 of 3) [Show all]SpeciesId(%)Len(aa)
XP_001110530.1 PREDICTED: protein S100-A8 isoform 3 M. mulatta 91.4 92
NP_001139616.1 S100A8 gene product C. lupus familiaris 78.7 88

GENE EXPRESSION
Tissues and development stages from this gene's sequences survey gene expression. Links to other NCBI expression resources.
Restricted Expression: adult [show more like this]
EST Profile: Approximate expression patterns inferred from EST sources.
[Show more entries with profiles like this]
GEO Profiles: Experimental gene expression data (Gene Expression Omnibus).
cDNA Sources: mouth; pharynx; bone marrow; blood; tonsil; ovary; stomach; brain; heart; spleen; uncharacterized tissue; lung; skin; mixed; prostate; mammary gland; bladder; connective tissue; uterus; muscle; larynx; liver; adipose tissue; eye; bone; pancreas; placenta; testis; nerve; esophagus; vascular; intestine; cervix; kidney; adrenal gland
MAPPING POSITION
Genomic location specified by transcript mapping, radiation hybrid mapping, genetic mapping or cytogenetic mapping.
Chromosome: 1
Map position: 1q21
UniSTS entry: Chr 1 RH68221 [Map Viewer]
UniSTS entry: Chr 1 RH11552 [Map Viewer]
SEQUENCES
Sequences representing this gene; mRNAs, ESTs, and gene predictions supported by transcribed sequences.

mRNA sequences (7)

BT007378.1 Homo sapiens S100 calcium binding protein A8 (calgranulin A) mRNA, complete cds P
NM_002964.4 Homo sapiens S100 calcium binding protein A8 (S100A8), mRNA PA
CR407674.1 Homo sapiens full open reading frame cDNA clone RZPDo834A1216D for gene S100A8, S100 calcium binding protein A8 (calgranulin A) complete cds, without stopcodon P
BC005928.2 Homo sapiens S100 calcium binding protein A8, mRNA (cDNA clone MGC:14536 IMAGE:4246359), complete cds PA
AK291328.1 Homo sapiens cDNA FLJ76560 complete cds, highly similar to Homo sapiens S100 calcium binding protein A8 (calgranulin A) (S100A8), mRNA PA
Y00278.1 Human mRNA for cystic fibrosis antigen (CFAg) PA
X06234.1 Human mRNA for calcium-binding protein in macrophages (MRP-8) macrophage migration inhibitory factor (MIF)-related protein PA

EST sequences (10 of 512) [Show all sequences]

AA903259.1 Clone IMAGE:1517295 uncharacterized tissue 3' read PA
AA969427.1 Clone IMAGE:1580567 mixed 3' read PA
AA897671.1 Clone IMAGE:1504436 mixed 3' read P
AI057505.1 Clone IMAGE:1653169 mixed 3' read A
AI126134.1 Clone IMAGE:1735496 testis 3' read PA
AI187047.1 Clone IMAGE:1741619 lung 3' read PA
AI188229.1 Clone IMAGE:1734524 testis 3' read
AI251743.1 Clone IMAGE:1854275 mixed 3' read PA
CB129405.1 Clone C1SNU17-5-C10 cervix 5' read PA
CB151169.1 Clone C1SNU17-25-F06 cervix 5' read A


Key to Symbols

P Has similarity to known Proteins (after translation)
A Contains a poly-Adenylation signal
S Sequence is a Suboptimal member of this cluster
M Clone is putatively CDS-complete by MGC criteria

 
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