> Sodium channel, non-voltage-gated 1, beta subunit (SCNN1B)
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UGID:222559     UniGene Hs.414614     Homo sapiens (human)   SCNN1B Order cDNA clone, Links
Sodium channel, non-voltage-gated 1, beta subunit (SCNN1B)

Human protein-coding gene SCNN1B. Represented by 114 ESTs from 58 cDNA libraries. EST representation biased toward adult. Corresponds to reference sequence NM_000336.2. [UniGene 222559 - Hs.414614]

SELECTED PROTEIN SIMILARITIES
Comparison of cluster transcripts with RefSeq proteins. The alignments can suggest function of the cluster.
Best Hits and Hits from model organismsSpeciesId(%)Len(aa)
NP_000327.2 SCNN1B gene product H. sapiens 100.0 639
NP_035455.1 Scnn1b gene product M. musculus 87.6 637
NP_001079258.1 amiloride-sensitive sodium channel subunit beta X. laevis 68.0 643
Other hits (2 of 17) [Show all]SpeciesId(%)Len(aa)
XP_001161438.2 PREDICTED: amiloride-sensitive sodium channel subunit beta isoform 1 P. troglodytes 98.5 681
XP_001093933.1 PREDICTED: amiloride-sensitive sodium channel subunit beta isoform 3 M. mulatta 98.0 639

GENE EXPRESSION
Tissues and development stages from this gene's sequences survey gene expression. Links to other NCBI expression resources.
Restricted Expression: adult [show more like this]
EST Profile: Approximate expression patterns inferred from EST sources.
[Show more entries with profiles like this]
GEO Profiles: Experimental gene expression data (Gene Expression Omnibus).
cDNA Sources: lung; kidney; salivary gland; mouth; mammary gland; intestine; mixed; placenta; uncharacterized tissue; pancreas; stomach; trachea; eye; brain; esophagus; lymph node; heart; uterus; pharynx; prostate; testis
MAPPING POSITION
Genomic location specified by transcript mapping, radiation hybrid mapping, genetic mapping or cytogenetic mapping.
Chromosome: 16
Map position: 16p12.2-p12.1
UniSTS entry: Chr 16 RH79175 [Map Viewer]
UniSTS entry: Chr 16 STS-X87159
SEQUENCES
Sequences representing this gene; mRNAs, ESTs, and gene predictions supported by transcribed sequences.

mRNA sequences (7)

NM_000336.2 Homo sapiens sodium channel, non-voltage-gated 1, beta subunit (SCNN1B), mRNA P
X87159.1 H.sapiens mRNA for beta subunit of epithelial amiloride-sensitive sodium channel PA
DQ402523.1 Homo sapiens nasal epithelial sodium channel beta subunit mRNA, complete cds P
AK313192.1 Homo sapiens cDNA, FLJ93691, highly similar to Homo sapiens sodium channel, nonvoltage-gated 1, beta (Liddle syndrome) (SCNN1B), mRNA P
AF260226.1 Homo sapiens epithelial sodium channel beta subunit (SCNN1B) mRNA, partial cds P
BC036352.1 Homo sapiens sodium channel, nonvoltage-gated 1, beta, mRNA (cDNA clone MGC:34556 IMAGE:5178288), complete cds PA
L36593.1 Homo sapiens kidney epithelial sodium channel beta subunit (beta hENaC) mRNA, complete cds P

EST sequences (10 of 114) [Show all sequences]

AI143640.1 Clone IMAGE:1705846 heart 3' read A
BX101884.1 Clone IMAGp998K175635_;_IMAGE:2275720 uterus A
AI242292.1 Clone IMAGE:1856692 mixed 3' read A
AI283195.1 Clone IMAGE:1872355 intestine 3' read A
AI304817.1 Clone IMAGE:1913223 intestine 3' read A
AI346878.1 Clone IMAGE:1926769 intestine 3' read A
AI468310.1 Clone IMAGE:2112886 prostate 3' read A
AI493803.1 Clone IMAGE:2030385 kidney 3' read A
AI572536.1 Clone IMAGE:2089116 mixed 3' read A
AI611207.1 Clone IMAGE:2264897 uterus 3' read A


Key to Symbols

P Has similarity to known Proteins (after translation)
A Contains a poly-Adenylation signal
S Sequence is a Suboptimal member of this cluster
M Clone is putatively CDS-complete by MGC criteria

 
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