> Nephrosis 2, idiopathic, steroid-resistant (podocin) (NPHS2)
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UGID:222064     UniGene Hs.412710     Homo sapiens (human)   NPHS2 Order cDNA clone, Links
Nephrosis 2, idiopathic, steroid-resistant (podocin) (NPHS2)

Human protein-coding gene NPHS2. Represented by 21 ESTs from 4 cDNA libraries. EST representation biased toward kidney; normal. Corresponds to reference sequence NM_014625.2. [UniGene 222064 - Hs.412710]

SELECTED PROTEIN SIMILARITIES
Comparison of cluster transcripts with RefSeq proteins. The alignments can suggest function of the cluster.
Best Hits and Hits from model organismsSpeciesId(%)Len(aa)
NP_055440.1 NPHS2 gene product H. sapiens 100.0 382
NP_569723.1 Nphs2 gene product M. musculus 87.3 384
NP_001080862.1 stomatin X. laevis 51.6 254
NP_571833.1 stom gene product D. rerio 46.6 277
NP_996512.1 CG33253, isoform A D. melanogaster 46.2 262
NP_509944.1 Protein STO-4 C. elegans 45.8 247
Other hits (2 of 38) [Show all]SpeciesId(%)Len(aa)
XP_002802082.1 PREDICTED: podocin-like isoform 1 M. mulatta 98.4 382
XP_003308663.2 PREDICTED: LOW QUALITY PROTEIN: podocin isoform 1 P. troglodytes 98.2 382

GENE EXPRESSION
Tissues and development stages from this gene's sequences survey gene expression. Links to other NCBI expression resources.
Restricted Expression: kidney [show more like this]
normal [show more like this]
EST Profile: Approximate expression patterns inferred from EST sources.
[Show more entries with profiles like this]
GEO Profiles: Experimental gene expression data (Gene Expression Omnibus).
cDNA Sources: kidney; mixed; uncharacterized tissue
MAPPING POSITION
Genomic location specified by transcript mapping, radiation hybrid mapping, genetic mapping or cytogenetic mapping.
Chromosome: 1
Map position: 1q25.2
SEQUENCES
Sequences representing this gene; mRNAs, ESTs, and gene predictions supported by transcribed sequences.

mRNA sequences (3)

AJ279254.1 Homo sapiens mRNA for podocin (NPHS2 gene) P
NM_014625.2 Homo sapiens nephrosis 2, idiopathic, steroid-resistant (podocin) (NPHS2), mRNA PA
BC029141.1 Homo sapiens nephrosis 2, idiopathic, steroid-resistant (podocin), mRNA (cDNA clone MGC:34362 IMAGE:5187188), complete cds PA

EST sequences (10 of 21) [Show all sequences]

BX095913.1 Clone IMAGp998E045693_;_IMAGE:2297835 kidney
AI590197.1 Clone IMAGE:2171770 kidney 3' read
AI590292.1 Clone IMAGE:2171663 kidney 3' read A
AI672038.1 Clone IMAGE:2283738 kidney 3' read A
AI767687.1 Clone IMAGE:2383052 kidney 3' read A
AI796031.1 Clone IMAGE:2383334 kidney 3' read A
AI913530.1 Clone IMAGE:2297835 kidney 3' read A
AW263080.1 Clone IMAGE:2695715 kidney 3' read A
AW271469.1 Clone IMAGE:2769663 kidney 3' read A
AW294225.1 Clone IMAGE:2726526 uncharacterized tissue 3' read A


Key to Symbols

P Has similarity to known Proteins (after translation)
A Contains a poly-Adenylation signal
S Sequence is a Suboptimal member of this cluster
M Clone is putatively CDS-complete by MGC criteria

 
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