> Ceramide synthase 1 (CERS1)
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UGID:221999     UniGene Hs.412355     Homo sapiens (human)   CERS1 Order cDNA clone, Links
Ceramide synthase 1 (CERS1)

Human protein-coding gene CERS1. Represented by 123 ESTs from 58 cDNA libraries. Corresponds to 3 reference sequences (different isoforms). [UniGene 221999 - Hs.412355]

SELECTED PROTEIN SIMILARITIES
Comparison of cluster transcripts with RefSeq proteins. The alignments can suggest function of the cluster.
Best Hits and Hits from model organismsSpeciesId(%)Len(aa)
NP_001483.3 GDF1 gene product H. sapiens 100.0 371
XP_524160.3 PREDICTED: LAG1 longevity assurance homolog 1 P. troglodytes 99.7 347
NP_619588.1 Cers1 gene product M. musculus 83.4 349
XP_003201015.1 PREDICTED: LAG1 longevity assurance homolog 1 D. rerio 68.6 340
Other hits (2 of 23) [Show all]SpeciesId(%)Len(aa)
XP_003915251.1 PREDICTED: LOW QUALITY PROTEIN: ceramide synthase 1 P. anubis 99.1 349
XP_001115596.2 PREDICTED: embryonic growth/differentiation factor 1-like M. mulatta 95.7 369

GENE EXPRESSION
Tissues and development stages from this gene's sequences survey gene expression. Links to other NCBI expression resources.
EST Profile: Approximate expression patterns inferred from EST sources.
[Show more entries with profiles like this]
GEO Profiles: Experimental gene expression data (Gene Expression Omnibus).
cDNA Sources: brain; uncharacterized tissue; pancreas; embryonic tissue; mixed; placenta; skin; intestine; testis; eye; muscle; lung; nerve; uterus; ascites; ovary; ganglia
MAPPING POSITION
Genomic location specified by transcript mapping, radiation hybrid mapping, genetic mapping or cytogenetic mapping.
Chromosome: 19
Map position: 19p12
UniSTS entry: GDF1
UniSTS entry: Chr 19 WI-14123 [Map Viewer]
SEQUENCES
Sequences representing this gene; mRNAs, ESTs, and gene predictions supported by transcribed sequences.

mRNA sequences (9)

NM_001492.4 Homo sapiens growth differentiation factor 1 (GDF1), mRNA P
NM_198207.2 Homo sapiens ceramide synthase 1 (CERS1), transcript variant 2, mRNA PA
BC084582.1 Homo sapiens LAG1 homolog, ceramide synthase 1, mRNA (cDNA clone MGC:90349 IMAGE:6192817), complete cds PA
AB209169.1 Homo sapiens mRNA for growth differentiation factor 1 variant protein P
NM_021267.3 Homo sapiens ceramide synthase 1 (CERS1), transcript variant 1, mRNA P
BC022450.1 Homo sapiens growth differentiation factor 1, mRNA (cDNA clone MGC:25992 IMAGE:4797772), complete cds PA
AK293463.1 Homo sapiens cDNA FLJ56956 complete cds, highly similar to LAG1 longevity assurance homolog 1 P
BC032615.1 Homo sapiens cDNA clone IMAGE:5557395, containing frame-shift errors PA
M62302.1 Human growth/differentiation factor 1 (GDF-1) mRNA, complete cds PA

EST sequences (10 of 123) [Show all sequences]

AI017572.1 Clone IMAGE:1627143 mixed 3' read A
AI143691.1 Clone IMAGE:1751022 brain 3' read A
AI085498.1 Clone IMAGE:1750560 brain 3' read P
AI362733.1 Clone IMAGE:2018283 brain 3' read P
AI651252.1 Clone IMAGE:2304222 uncharacterized tissue 3' read A
AI671814.1 Clone IMAGE:2307566 uncharacterized tissue 3' read A
AI671986.1 Clone IMAGE:2311199 uncharacterized tissue 3' read A
R56800.1 Clone IMAGE:41118 brain 3' read A
AI887100.1 Clone IMAGE:2428124 uterus 3' read
AI936592.1 Clone IMAGE:2329600 mixed 3' read PA


Key to Symbols

P Has similarity to known Proteins (after translation)
A Contains a poly-Adenylation signal
S Sequence is a Suboptimal member of this cluster
M Clone is putatively CDS-complete by MGC criteria

 
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