RAD52 homolog (S. cerevisiae) (RAD52)

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UGID:221561 UniGene Hs.410355 Homo sapiens (human) RAD52

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RAD52 homolog (S. cerevisiae) (RAD52)

Human protein-coding gene RAD52. Represented by 83 ESTs from 66 cDNA libraries. Corresponds to reference sequence NM_134424.2. [UniGene 221561 - Hs.410355]

SELECTED PROTEIN SIMILARITIES

Comparison of cluster transcripts with RefSeq proteins. The alignments can suggest function of the cluster.

Best Hits and Hits from model organisms		Species	Id(%)	Len(aa)
NP_602296.2 Conserved domains (CDD) Gene summary Protein sequence Protein/EST matches (ProtEST) Protein/protein matches (BLink)	RAD52 gene product	H. sapiens	100.0	417
NP_035366.2 Conserved domains (CDD) Gene summary Protein sequence Protein/EST matches (ProtEST) Protein/protein matches (BLink)	Rad52 gene product	M. musculus	84.0	418
NP_001089585.1 Conserved domains (CDD) Gene summary Protein sequence Protein/EST matches (ProtEST) Protein/protein matches (BLink)	RAD52 homolog	X. laevis	74.3	411
NP_001019622.1 Conserved domains (CDD) Gene summary Protein sequence Protein/EST matches (ProtEST) Protein/protein matches (BLink)	rad52 gene product	D. rerio	68.4	396
XP_961065.1 Conserved domains (CDD) Gene summary Protein sequence Protein/EST matches (ProtEST) Protein/protein matches (BLink)	hypothetical protein NCU04275	N. crassa	55.6	151
NP_013680.2 Conserved domains (CDD) Gene summary Protein sequence Protein/EST matches (ProtEST) Protein/protein matches (BLink)	recombinase RAD52	S. cerevisiae	55.0	140
Other hits (2 of 28) [Show all]		Species	Id(%)	Len(aa)
XP_522311.4 Conserved domains (CDD) Gene summary Protein sequence Protein/EST matches (ProtEST) Protein/protein matches (BLink)	PREDICTED: DNA repair protein RAD52 homolog isoform 3	P. troglodytes	97.8	416
XP_003905838.1 Conserved domains (CDD) Gene summary Protein sequence Protein/EST matches (ProtEST) Protein/protein matches (BLink)	PREDICTED: DNA repair protein RAD52 homolog	P. anubis	96.4	418

GENE EXPRESSION

Tissues and development stages from this gene's sequences survey gene expression. Links to other NCBI expression resources.

	EST Profile:	Approximate expression patterns inferred from EST sources. [Show more entries with profiles like this]
	GEO Profiles:	Experimental gene expression data (Gene Expression Omnibus).
	cDNA Sources:	brain; placenta; kidney; pharynx; intestine; bone marrow; testis; skin; mammary gland; lymph node; uncharacterized tissue; mixed; connective tissue; embryonic tissue; blood; mouth; spleen; thymus; lung; uterus; prostate; heart; bone; adrenal gland

MAPPING POSITION

Genomic location specified by transcript mapping, radiation hybrid mapping, genetic mapping or cytogenetic mapping.

Chromosome:	12
Map position:	12p13-p12.2
UniSTS entry:	Chr 12	WI-9332
UniSTS entry:	Chr 12	SHGC-64053

SEQUENCES

Sequences representing this gene; mRNAs, ESTs, and gene predictions supported by transcribed sequences.

mRNA sequences (17)

BC042136.1	Homo sapiens RAD52 homolog (S. cerevisiae), mRNA (cDNA clone IMAGE:5802809), with apparent retained intron	PA
AF125950.1	Homo sapiens DNA repair protein RAD52 beta isoform (RAD52) mRNA, alternatively spliced, complete cds	P
AY540753.1	Homo sapiens rhabdomyosarcoma antigen MU-RMS-40.23 (RAD52) mRNA, complete cds	P
U12134.1	Human DNA damage repair and recombination protein RAD52 mRNA, complete cds	P
BC104015.1	Homo sapiens RAD52 homolog (S. cerevisiae), mRNA (cDNA clone IMAGE:40024504), partial cds	P
BC104017.1	Homo sapiens RAD52 homolog (S. cerevisiae), mRNA (cDNA clone IMAGE:40024509), partial cds	P
BC114507.1	Homo sapiens RAD52 homolog (S. cerevisiae), mRNA (cDNA clone IMAGE:40024511)	P
BC114954.1	Homo sapiens RAD52 homolog (S. cerevisiae), mRNA (cDNA clone IMAGE:40024512), complete cds	P
L33262.1	Homo sapiens DNA repair and recombination homologue (RAD52) gene, complete cds	P
AK290047.1	Homo sapiens cDNA FLJ77029 complete cds, highly similar to Homo sapiens RAD52 homolog (S. cerevisiae) (RAD52), transcript variant alpha, mRNA	P
AK292160.1	Homo sapiens cDNA FLJ76573 complete cds, highly similar to Homo sapiens RAD52 homolog (S. cerevisiae) (RAD52), transcript variant gamma, mRNA	P
AK312026.1	Homo sapiens cDNA, FLJ92302, Homo sapiens RAD52 homolog (S. cerevisiae) (RAD52), transcriptvariant delta, mRNA	P
NM_134424.2	Homo sapiens RAD52 homolog (S. cerevisiae) (RAD52), mRNA	P
BC144458.1	Homo sapiens cDNA clone IMAGE:9052984	P
AK299283.1	Homo sapiens cDNA FLJ57177 complete cds, highly similar to DNA repair protein RAD52 homolog	P
AK294709.1	Homo sapiens cDNA FLJ56674 complete cds, highly similar to DNA repair protein RAD52 homolog	P
U27516.1	Human recombination protein RAD52 mRNA, complete cds	P

EST sequences (10 of 83) [Show all sequences]

AI039779.1	Clone IMAGE:1659628	embryonic tissue	3' read
AI056288.1	Clone IMAGE:1674200	mixed	3' read	A
AI078218.1	Clone IMAGE:1675900	mixed	3' read	P
AI078228.1	Clone IMAGE:1675901	mixed	3' read	P
AI341090.1	Clone IMAGE:2009160	uncharacterized tissue	3' read	A
AI675319.1	Clone IMAGE:2315869	prostate	3' read	A
R58529.1	Clone G4028	heart	5' read
AI859172.1	Clone IMAGE:2429897	brain	3' read	A
BX327490.1	Clone CS0DJ015YB06	blood	5' read	P
BX350352.2	Clone CS0DJ015YB06	blood	3' read

Key to Symbols

P Has similarity to known Proteins (after translation)
A Contains a poly-Adenylation signal
S Sequence is a Suboptimal member of this cluster
M Clone is putatively CDS-complete by MGC criteria