> 1-acylglycerol-3-phosphate O-acyltransferase 1 (AGPAT1)
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UGID:221267     UniGene Hs.409230     Homo sapiens (human)   AGPAT1
1-acylglycerol-3-phosphate O-acyltransferase 1 (AGPAT1)

Human protein-coding gene AGPAT1. Represented by 627 ESTs from 270 cDNA libraries. Corresponds to 2 reference sequences (different isoforms). [UniGene 221267 - Hs.409230]

SELECTED PROTEIN SIMILARITIES
Comparison of cluster transcripts with RefSeq proteins. The alignments can suggest function of the cluster.
Best Hits and Hits from model organismsSpeciesId(%)Len(aa)
XP_003897448.1 PREDICTED: 1-acyl-sn-glycerol-3-phosphate acyltransferase alpha isoform 1 P. anubis 100.0 286
XP_001114553.1 PREDICTED: 1-acyl-sn-glycerol-3-phosphate acyltransferase alpha-like isoform 3 M. mulatta 100.0 282
XP_518375.2 PREDICTED: 1-acyl-sn-glycerol-3-phosphate acyltransferase alpha isoform 12 P. troglodytes 100.0 282
NP_116130.2 AGPAT1 gene product H. sapiens 100.0 282
XP_001492118.2 PREDICTED: 1-acyl-sn-glycerol-3-phosphate acyltransferase alpha-like E. caballus 99.7 286
NP_803484.1 AGPAT1 gene product B. taurus 99.7 286
XP_860706.2 PREDICTED: 1-acyl-sn-glycerol-3-phosphate acyltransferase alpha isoform 3 C. lupus familiaris 99.7 284
XP_002714347.1 PREDICTED: 1-acylglycerol-3-phosphate O-acyltransferase 1 O. cuniculus 99.7 284
NP_001156851.1 1-acyl-sn-glycerol-3-phosphate acyltransferase alpha isoform 1 M. musculus 96.1 282
NP_001087689.1 1-acylglycerol-3-phosphate O-acyltransferase 1 (lysophosphatidic acid acyltransferase, alpha) X. laevis 79.8 268
NP_001071200.1 agpat2 gene product D. rerio 60.2 264
NP_572828.1 CG3812, isoform A D. melanogaster 47.3 207
Other hits (2 of 23) [Show all]SpeciesId(%)Len(aa)
XP_004018969.1 PREDICTED: 1-acyl-sn-glycerol-3-phosphate acyltransferase alpha O. aries 98.8 319
NP_997623.1 Agpat1 gene product R. norvegicus 97.9 281

GENE EXPRESSION
Tissues and development stages from this gene's sequences survey gene expression. Links to other NCBI expression resources.
EST Profile: Approximate expression patterns inferred from EST sources.
[Show more entries with profiles like this]
GEO Profiles: Experimental gene expression data (Gene Expression Omnibus).
cDNA Sources: brain; skin; uncharacterized tissue; placenta; bladder; lymph; thymus; eye; spleen; testis; intestine; connective tissue; esophagus; ovary; heart; embryonic tissue; epididymis; lymph node; lung; uterus; kidney; blood; pancreas; adrenal gland; vascular; stomach; liver; prostate; pituitary gland; mixed; cervix; mammary gland; muscle; thyroid; nerve; salivary gland; bone; ascites; spinal cord; bone marrow; mouth; larynx; ganglia
MAPPING POSITION
Genomic location specified by transcript mapping, radiation hybrid mapping, genetic mapping or cytogenetic mapping.
Chromosome: 6
Map position: 6p21.3
UniSTS entry: Chr 6 RH91426
UniSTS entry: Chr 6 D6S1412 [Map Viewer]
UniSTS entry: Chr 6 MARC_31849-31850:1068218042:1
UniSTS entry: Chr 6 D6S1879 [Map Viewer]
SEQUENCES
Sequences representing this gene; mRNAs, ESTs, and gene predictions supported by transcribed sequences.

mRNA sequences (16)

AK129818.1 Homo sapiens cDNA FLJ26307 fis, clone DMC08287, highly similar to 1-acyl-sn-glycerol-3-phosphate acyltransferase alpha (EC 2.3.1.51) P
NM_006411.3 Homo sapiens 1-acylglycerol-3-phosphate O-acyltransferase 1 (AGPAT1), transcript variant 1, mRNA PA
BC090849.1 Homo sapiens 1-acylglycerol-3-phosphate O-acyltransferase 1 (lysophosphatidic acid acyltransferase, alpha), mRNA (cDNA clone MGC:102686 IMAGE:6169543), complete cds PA
BC003007.1 Homo sapiens 1-acylglycerol-3-phosphate O-acyltransferase 1 (lysophosphatidic acid acyltransferase, alpha), mRNA (cDNA clone MGC:4007 IMAGE:2822348), complete cds PA
BC002402.2 Homo sapiens 1-acylglycerol-3-phosphate O-acyltransferase 1 (lysophosphatidic acid acyltransferase, alpha), mRNA (cDNA clone MGC:8511 IMAGE:2822348), complete cds PA
BC004310.1 Homo sapiens 1-acylglycerol-3-phosphate O-acyltransferase 1 (lysophosphatidic acid acyltransferase, alpha), mRNA (cDNA clone MGC:10915 IMAGE:3627439), complete cds PA
BC006818.1 Homo sapiens 1-acylglycerol-3-phosphate O-acyltransferase 1 (lysophosphatidic acid acyltransferase, alpha), mRNA (cDNA clone IMAGE:3448169) A
NM_032741.4 Homo sapiens 1-acylglycerol-3-phosphate O-acyltransferase 1 (AGPAT1), transcript variant 2, mRNA PA
AK058025.1 Homo sapiens cDNA FLJ25296 fis, clone STM07640, highly similar to 1-ACYL-SN-GLYCEROL-3-PHOSPHATE ACYLTRANSFERASE ALPHA (EC 2.3.1.51) P
AK056346.1 Homo sapiens cDNA FLJ31784 fis, clone NT2RI2008481, highly similar to 1-acyl-sn-glycerol-3-phosphate acyltransferase alpha (EC 2.3.1.51) P
AK299252.1 Homo sapiens cDNA FLJ54610 complete cds, highly similar to 1-acyl-sn-glycerol-3-phosphate acyltransferase alpha (EC 2.3.1.51) P
AK315950.1 Homo sapiens cDNA, FLJ78849 complete cds, highly similar to 1-acyl-sn-glycerol-3-phosphate acyltransferase alpha (EC 2.3.1.51) P
U56417.1 Human lysophosphatidic acid acyltransferase-alpha mRNA, complete cds PA
U75971.1 Homo sapiens putative lysophospholipid acyltransferase mRNA, complete cds P
AF007145.1 Homo sapiens clone 23552 unknown mRNA, partial cds PA
Y09565.1 H.sapiens mRNA for 1-acylglycerol-3-phosphate O-acyltransferase PA

EST sequences (10 of 627) [Show all sequences]

AI001171.1 Clone IMAGE:1637744 mammary gland 3' read A
R17212.1 Clone IMAGE:31938 brain 5' read P
AA922914.1 Clone IMAGE:1457408 intestine 3' read A
AI128547.1 Clone IMAGE:1714770 placenta 3' read A
CB044582.1 Clone IMAGE:3217944 intestine 3' read A
CB044583.1 Clone IMAGE:3217944 intestine 5' read P
AI193422.1 Clone IMAGE:1743179 lung 3' read A
AI208159.1 Clone IMAGE:1837026 testis 3' read A
AI220581.1 Clone IMAGE:1839046 testis 3' read A
CB157920.1 Clone L18POOL1n1-5-G10 liver 5' read


Key to Symbols

P Has similarity to known Proteins (after translation)
A Contains a poly-Adenylation signal
S Sequence is a Suboptimal member of this cluster
M Clone is putatively CDS-complete by MGC criteria

 
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