> Complement component 2 (C2)
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UGID:221184     UniGene Hs.408903     Homo sapiens (human)   C2 Order cDNA clone, Links
Complement component 2 (C2)

Human protein-coding gene C2. Represented by 464 ESTs from 157 cDNA libraries. EST representation biased toward juvenile. Corresponds to 4 reference sequences (different isoforms). [UniGene 221184 - Hs.408903]

SELECTED PROTEIN SIMILARITIES
Comparison of cluster transcripts with RefSeq proteins. The alignments can suggest function of the cluster.
Best Hits and Hits from model organismsSpeciesId(%)Len(aa)
NP_000054.2 C2 gene product H. sapiens 100.0 751
XP_003311224.1 PREDICTED: complement C2 isoform 1 P. troglodytes 99.9 751
NP_038512.2 complement C2 precursor M. musculus 79.9 759
NP_001079047.1 complement factor B precursor X. laevis 45.8 192
Other hits (2 of 15) [Show all]SpeciesId(%)Len(aa)
XP_001113553.2 PREDICTED: complement factor B isoform 1 M. mulatta 87.9 701
XP_003897434.1 PREDICTED: complement factor B P. anubis 87.9 701

GENE EXPRESSION
Tissues and development stages from this gene's sequences survey gene expression. Links to other NCBI expression resources.
Restricted Expression: juvenile [show more like this]
EST Profile: Approximate expression patterns inferred from EST sources.
[Show more entries with profiles like this]
GEO Profiles: Experimental gene expression data (Gene Expression Omnibus).
cDNA Sources: liver; lung; placenta; connective tissue; uncharacterized tissue; brain; spleen; intestine; uterus; mouth; cervix; esophagus; trachea; mixed; kidney; prostate; heart; ovary; adrenal gland; adipose tissue; skin; blood; stomach; larynx; ganglia; eye; thymus; testis; pancreas; mammary gland; muscle; nerve; bone; lymph node
MAPPING POSITION
Genomic location specified by transcript mapping, radiation hybrid mapping, genetic mapping or cytogenetic mapping.
Chromosome: 6
Map position: 6p21.3
UniSTS entry: Chr 6 WI-8686 [Map Viewer]
UniSTS entry: Chr 6 RH18075
SEQUENCES
Sequences representing this gene; mRNAs, ESTs, and gene predictions supported by transcribed sequences.

mRNA sequences (14)

BC043484.1 Homo sapiens complement component 2, mRNA (cDNA clone MGC:49826 IMAGE:5763774), complete cds PA
NM_000063.4 Homo sapiens complement component 2 (C2), transcript variant 1, mRNA PA
AK222783.1 Homo sapiens mRNA for complement component 2 precursor variant, clone: HEP01788 PA
AK222537.1 Homo sapiens mRNA for complement component 2 precursor variant, clone: adSE01995 PA
X04481.1 Human mRNA for complement component C2 P
AK307930.1 Homo sapiens cDNA, FLJ97878 P
AK312581.1 Homo sapiens cDNA, FLJ92956, Homo sapiens complement component 2 (C2), mRNA P
AK096258.1 Homo sapiens cDNA FLJ38939 fis, clone NT2NE2015747, highly similar to COMPLEMENT C2 PRECURSOR (EC 3.4.21.43) P
AK300892.1 Homo sapiens cDNA FLJ54076 complete cds, highly similar to Complement C2 precursor (EC 3.4.21.43) PA
AK298311.1 Homo sapiens cDNA FLJ59728 complete cds, highly similar to Complement C2 precursor (EC 3.4.21.43) PA
AK298808.1 Homo sapiens cDNA FLJ54376 complete cds, highly similar to Complement C2 precursor (EC 3.4.21.43) P
NM_001145903.1 Homo sapiens complement component 2 (C2), transcript variant 2, mRNA PA
NM_001178063.1 Homo sapiens complement component 2 (C2), transcript variant 3, mRNA PA
NR_073063.1 Homo sapiens complement component 2 (C2), transcript variant 4, non-coding RNA PA

EST sequences (10 of 464) [Show all sequences]

AA928341.1 Clone IMAGE:1559980 intestine 3' read PA
AI052452.1 Clone IMAGE:1674688 mixed 3' read A
AA947337.1 Clone IMAGE:1589713 kidney 3' read A
AI077378.1 Clone IMAGE:1672852 mixed 3' read PA
AI141303.1 Clone IMAGE:1669324 brain 3' read PA
AI141304.1 Clone IMAGE:1669326 brain 3' read A
AI251811.1 Clone IMAGE:1978067 brain 3' read A
CB153379.1 Clone L17N670205-2-D02 liver 5' read P
CB147249.1 Clone L7N800102-17-D08 liver 5' read P
T25929.1 thymus


Key to Symbols

P Has similarity to known Proteins (after translation)
A Contains a poly-Adenylation signal
S Sequence is a Suboptimal member of this cluster
M Clone is putatively CDS-complete by MGC criteria

 
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