NADH dehydrogenase (ubiquinone) Fe-S protein 6, 13kDa (NADH-coenzyme Q reductase) (NDUFS6)

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UGID:220978 UniGene Hs.408257 Homo sapiens (human) NDUFS6

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NADH dehydrogenase (ubiquinone) Fe-S protein 6, 13kDa (NADH-coenzyme Q reductase) (NDUFS6)

Human protein-coding gene NDUFS6. Represented by 297 ESTs from 143 cDNA libraries. Corresponds to reference sequence NM_004553.4. [UniGene 220978 - Hs.408257]

SELECTED PROTEIN SIMILARITIES

Comparison of cluster transcripts with RefSeq proteins. The alignments can suggest function of the cluster.

Best Hits and Hits from model organisms		Species	Id(%)	Len(aa)
NP_001123606.1 Conserved domains (CDD) Gene summary Protein sequence Protein/EST matches (ProtEST) Protein/protein matches (BLink)	NDUFS6 gene product	P. troglodytes	100.0	123
NP_004544.1 Conserved domains (CDD) Gene summary Protein sequence Protein/EST matches (ProtEST) Protein/protein matches (BLink)	NDUFS6 gene product	H. sapiens	100.0	123
NP_035018.1 Conserved domains (CDD) Gene summary Protein sequence Protein/EST matches (ProtEST) Protein/protein matches (BLink)	NADH dehydrogenase [ubiquinone] iron-sulfur protein 6, mitochondrial precursor	M. musculus	89.7	115
NP_001085631.1 Conserved domains (CDD) Gene summary Protein sequence Protein/EST matches (ProtEST) Protein/protein matches (BLink)	NADH dehydrogenase (ubiquinone) Fe-S protein 6, 13kDa (NADH-coenzyme Q reductase)	X. laevis	80.2	100
NP_001004651.1 Conserved domains (CDD) Gene summary Protein sequence Protein/EST matches (ProtEST) Protein/protein matches (BLink)	ndufs6 gene product	D. rerio	78.0	99
Other hits (2 of 18) [Show all]		Species	Id(%)	Len(aa)
XP_001105649.1 Conserved domains (CDD) Gene summary Protein sequence Protein/EST matches (ProtEST) Protein/protein matches (BLink)	PREDICTED: NADH dehydrogenase [ubiquinone] iron-sulfur protein 6, mitochondrial-like isoform 2	M. mulatta	96.8	123
XP_003899520.1 Conserved domains (CDD) Gene summary Protein sequence Protein/EST matches (ProtEST) Protein/protein matches (BLink)	PREDICTED: NADH dehydrogenase [ubiquinone] iron-sulfur protein 6, mitochondrial	P. anubis	96.8	123

GENE EXPRESSION

Tissues and development stages from this gene's sequences survey gene expression. Links to other NCBI expression resources.

	EST Profile:	Approximate expression patterns inferred from EST sources. [Show more entries with profiles like this]
	GEO Profiles:	Experimental gene expression data (Gene Expression Omnibus).
	cDNA Sources:	prostate; mixed; brain; embryonic tissue; uterus; liver; muscle; lung; eye; lymph; placenta; testis; spleen; bone; mouth; mammary gland; bladder; ascites; lymph node; pancreas; intestine; ovary; kidney; uncharacterized tissue; vascular; blood; heart; skin; connective tissue; stomach; adrenal gland; bone marrow; salivary gland; pharynx; pineal gland

MAPPING POSITION

Genomic location specified by transcript mapping, radiation hybrid mapping, genetic mapping or cytogenetic mapping.

Chromosome:	5
Map position:	5p15.33
UniSTS entry:	Chr 5	RH41903	[Map Viewer]
UniSTS entry:	Chr 5	D5S2243E

SEQUENCES

Sequences representing this gene; mRNAs, ESTs, and gene predictions supported by transcribed sequences.

mRNA sequences (6)

AF044959.1	Homo sapiens NADH:ubiquinone oxidoreductase NDUFS6 subunit mRNA, nuclear gene encoding mitochondrial protein, complete cds	PA
BC046155.2	Homo sapiens NADH dehydrogenase (ubiquinone) Fe-S protein 6, 13kDa (NADH-coenzyme Q reductase), mRNA (cDNA clone MGC:57685 IMAGE:6047460), complete cds	PA
NM_004553.4	Homo sapiens NADH dehydrogenase (ubiquinone) Fe-S protein 6, 13kDa (NADH-coenzyme Q reductase) (NDUFS6), nuclear gene encoding mitochondrial protein, mRNA	PA
CR456880.1	Homo sapiens full open reading frame cDNA clone RZPDo834B017D for gene NDUFS6, NADH dehydrogenase (ubiquinone) Fe-S protein 6, 13kDa (NADH-coenzyme Q reductase); complete cds, incl. stopcodon	P
AK022503.1	Homo sapiens cDNA FLJ12441 fis, clone NT2RM1000132, highly similar to NADH-ubiquinone oxidoreductase 13 kDa-A subunit, mitochondrial precursor (EC 1.6.5.3)	P
BC038664.1	Homo sapiens NADH dehydrogenase (ubiquinone) Fe-S protein 6, 13kDa (NADH-coenzyme Q reductase), mRNA (cDNA clone MGC:40334 IMAGE:5204222), complete cds	PA

EST sequences (10 of 297) [Show all sequences]

AA978342.1	Clone IMAGE:1588784	kidney	3' read	PA
AA977284.1	Clone IMAGE:1589962	kidney	3' read	PA
AA994848.1	Clone IMAGE:1632033	mammary gland	3' read	PA
AI017668.1	Clone IMAGE:1635947	kidney	3' read	PA
AI024545.1	Clone IMAGE:1639627	testis	3' read	A
AI127097.1	Clone IMAGE:1708089	heart	3' read	A
CB048635.1	Clone IMAGE:3270795	prostate	3' read	A
BX108253.1	Clone IMAGp998B15692_;_IMAGE:307886	lung		PA
AI191340.1	Clone IMAGE:1740655	lung	3' read	PA
CB106827.1	Clone L3SNU475-11-D05	liver	5' read	PA

Key to Symbols

P Has similarity to known Proteins (after translation)
A Contains a poly-Adenylation signal
S Sequence is a Suboptimal member of this cluster
M Clone is putatively CDS-complete by MGC criteria