> FK506 binding protein 5 (FKBP5)
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UGID:220541     UniGene Hs.407190     Homo sapiens (human)   FKBP5 Order cDNA clone, Links
FK506 binding protein 5 (FKBP5)

Human protein-coding gene FKBP5. Represented by 542 ESTs from 222 cDNA libraries. Corresponds to 5 reference sequences (different isoforms). [UniGene 220541 - Hs.407190]

SELECTED PROTEIN SIMILARITIES
Comparison of cluster transcripts with RefSeq proteins. The alignments can suggest function of the cluster.
Best Hits and Hits from model organismsSpeciesId(%)Len(aa)
XP_001172420.1 PREDICTED: peptidyl-prolyl cis-trans isomerase FKBP5 isoform 2 P. troglodytes 100.0 456
NP_001139247.1 FKBP5 gene product H. sapiens 100.0 456
XP_003897547.1 PREDICTED: peptidyl-prolyl cis-trans isomerase FKBP5-like P. anubis 99.6 277
NP_034350.1 Fkbp5 gene product M. musculus 92.5 455
NP_998314.1 fkbp5 gene product D. rerio 70.6 422
NP_001084593.1 FK506 binding protein 4, 59kDa X. laevis 66.0 421
NP_524895.2 FK506-binding protein FKBP59 D. melanogaster 53.8 240
NP_508026.1 Protein FKB-6 C. elegans 50.8 199
NP_189160.3 rotamase FKBP 1 A. thaliana 45.3 192
Other hits (2 of 41) [Show all]SpeciesId(%)Len(aa)
XP_001929450.4 PREDICTED: LOW QUALITY PROTEIN: peptidyl-prolyl cis-trans isomerase FKBP5 S. scrofa 98.9 463
XP_004018821.1 PREDICTED: peptidyl-prolyl cis-trans isomerase FKBP5 O. aries 98.9 456

GENE EXPRESSION
Tissues and development stages from this gene's sequences survey gene expression. Links to other NCBI expression resources.
EST Profile: Approximate expression patterns inferred from EST sources.
[Show more entries with profiles like this]
GEO Profiles: Experimental gene expression data (Gene Expression Omnibus).
cDNA Sources: brain; thymus; testis; uterus; uncharacterized tissue; trachea; liver; kidney; parathyroid; blood; mixed; prostate; eye; lung; spleen; intestine; embryonic tissue; vascular; mouth; muscle; connective tissue; pancreas; stomach; skin; larynx; pharynx; bone; ovary; mammary gland; placenta; lymph node; cervix; thyroid; heart; esophagus; bone marrow; pituitary gland
MAPPING POSITION
Genomic location specified by transcript mapping, radiation hybrid mapping, genetic mapping or cytogenetic mapping.
Chromosome: 6
Map position: 6p21.31
UniSTS entry: Chr 6 SGC32907 [Map Viewer]
UniSTS entry: Chr 6 SHGC-33930 [Map Viewer]
UniSTS entry: Chr 6 STS-R01175 [Map Viewer]
UniSTS entry: Chr 6 SHGC-132511
UniSTS entry: Chr 6 D6S1111E
UniSTS entry: Chr 6 RH47153
UniSTS entry: Chr 6 SHGC-32701 [Map Viewer]
UniSTS entry: Chr 6 FKBP5_v427
UniSTS entry: Chr 1 GDB:631813
UniSTS entry: Chr 1 D11S3114
SEQUENCES
Sequences representing this gene; mRNAs, ESTs, and gene predictions supported by transcribed sequences.

mRNA sequences (23)

BC042605.1 Homo sapiens FK506 binding protein 5, mRNA (cDNA clone MGC:34489 IMAGE:4539929), complete cds PA
BX647390.1 Homo sapiens mRNA; cDNA DKFZp686G08144 (from clone DKFZp686G08144) PA
NM_004117.3 Homo sapiens FK506 binding protein 5 (FKBP5), transcript variant 1, mRNA PA
AL122066.1 Homo sapiens mRNA; cDNA DKFZp434P171 (from clone DKFZp434P171) A
AB209893.1 Homo sapiens mRNA for FK506 binding protein 5 variant protein P
AK222807.1 Homo sapiens mRNA for FK506 binding protein 5 variant, clone: HEP04108 P
BC111050.1 Homo sapiens FK506 binding protein 5, mRNA (cDNA clone MGC:111006 IMAGE:5723416), complete cds PA
U42031.1 Human 54 kDa progesterone receptor-associated immunophilin FKBP54 mRNA, partial cds PA
AF194172.1 Homo sapiens androgen-regulated protein 6 (AIG6) mRNA, complete cds P
AK312422.1 Homo sapiens cDNA, FLJ92761, Homo sapiens FK506 binding protein 5 (FKBP5), mRNA P
AK093304.1 Homo sapiens cDNA FLJ35985 fis, clone TESTI2014248
BC034770.1 Homo sapiens cDNA clone IMAGE:5171802 A
X97300.1 H.sapiens mRNA for Ptg-10 protein
AK303356.1 Homo sapiens cDNA FLJ58213 complete cds, highly similar to FK506-binding protein 5 (EC 5.2.1.8) PA
AK302704.1 Homo sapiens cDNA FLJ57237 complete cds, highly similar to FK506-binding protein 5 (EC 5.2.1.8) P
NM_001145777.1 Homo sapiens FK506 binding protein 5 (FKBP5), transcript variant 4, mRNA P
NM_001145776.1 Homo sapiens FK506 binding protein 5 (FKBP5), transcript variant 3, mRNA PA
NM_001145775.1 Homo sapiens FK506 binding protein 5 (FKBP5), transcript variant 2, mRNA PA
HM245391.1 Homo sapiens FKBP5-TMPRSS2 breakpoint junction mRNA sequence P
HM245388.1 Homo sapiens TMPRSS2-FKBP5 breakpoint junction transcript variant 2 and FKBP5-ERG breakpoint junction transcript variant 2 mRNA sequence P
HM245387.1 Homo sapiens TMPRSS2-FKBP5 breakpoint junction transcript variant 1 and FKBP5-ERG breakpoint junction transcript variant 1 mRNA sequence
U71321.1 Human FK506-binding protein FKBP51 mRNA, complete cds P
NR_027117.1 Homo sapiens uncharacterized LOC285847 (LOC285847), non-coding RNA A

EST sequences (10 of 542) [Show all sequences]

AA971975.1 Clone IMAGE:1582729 mixed 3' read
AA976417.1 Clone IMAGE:1589835 kidney 3' read
AI033456.1 Clone IMAGE:1654532 mixed 3' read
AI088938.1 Clone IMAGE:1687447 brain 3' read
AI090508.1 Clone IMAGE:1692091 heart 3' read A
AI096484.1 Clone IMAGE:1685665 brain 3' read A
AI130821.1 Clone IMAGE:1709146 heart 3' read A
CB049879.1 Clone IMAGE:3271862 prostate 3' read A
AI148301.1 Clone IMAGE:1697835 uterus 3' read A
BX115688.1 Clone IMAGp998F12391_;_IMAGE:202763 mixed


Key to Symbols

P Has similarity to known Proteins (after translation)
A Contains a poly-Adenylation signal
S Sequence is a Suboptimal member of this cluster
M Clone is putatively CDS-complete by MGC criteria

 
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