> Splicing factor 3a, subunit 1, 120kDa (SF3A1)
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UGID:220024     UniGene Hs.406277     Homo sapiens (human)   SF3A1 Order cDNA clone, Links
Splicing factor 3a, subunit 1, 120kDa (SF3A1)

Human protein-coding gene SF3A1. Represented by 1232 ESTs from 355 cDNA libraries. Corresponds to 2 reference sequences (different isoforms). [UniGene 220024 - Hs.406277]

SELECTED PROTEIN SIMILARITIES
Comparison of cluster transcripts with RefSeq proteins. The alignments can suggest function of the cluster.
Best Hits and Hits from model organismsSpeciesId(%)Len(aa)
XP_003905462.1 PREDICTED: splicing factor 3A subunit 1 P. anubis 100.0 792
XP_515067.2 PREDICTED: splicing factor 3A subunit 1 isoform 3 P. troglodytes 100.0 792
NP_005868.1 SF3A1 gene product H. sapiens 100.0 792
XP_001109090.1 PREDICTED: splicing factor 3A subunit 1 isoform 3 M. mulatta 99.9 792
XP_001498274.1 PREDICTED: splicing factor 3A subunit 1 isoform 1 E. caballus 99.6 792
XP_003483500.1 PREDICTED: splicing factor 3A subunit 1 isoform 1 S. scrofa 99.6 792
NP_001074979.1 SF3A1 gene product B. taurus 99.6 792
XP_002721215.1 PREDICTED: splicing factor 3a, subunit 1, 120kDa isoform 1 O. cuniculus 99.5 792
NP_080451.4 Sf3a1 gene product M. musculus 99.5 790
NP_956388.1 sf3a1 gene product D. rerio 93.3 779
NP_001085709.1 MGC80562 protein X. laevis 92.9 801
NP_650583.1 CG16941 D. melanogaster 65.7 777
NP_493746.1 Protein PRP-21 C. elegans 54.8 336
NP_172916.1 SWAP (Suppressor-of-White-APricot)/surp domain-containing protein A. thaliana 49.0 202
XP_001691370.1 SF3A1 splicing factor 3a, subunit 1 C. reinhardtii 45.1 164
Other hits (2 of 44) [Show all]SpeciesId(%)Len(aa)
XP_534733.2 PREDICTED: splicing factor 3A subunit 1 isoform 1 C. lupus familiaris 99.4 792
NP_001100705.1 splicing factor 3A subunit 1 R. norvegicus 99.4 790

GENE EXPRESSION
Tissues and development stages from this gene's sequences survey gene expression. Links to other NCBI expression resources.
EST Profile: Approximate expression patterns inferred from EST sources.
[Show more entries with profiles like this]
GEO Profiles: Experimental gene expression data (Gene Expression Omnibus).
cDNA Sources: brain; testis; uncharacterized tissue; thymus; kidney; lung; eye; skin; liver; lymph node; uterus; placenta; prostate; embryonic tissue; connective tissue; pancreas; mammary gland; mixed; mouth; intestine; vascular; blood; bladder; tonsil; spleen; ovary; cervix; trachea; muscle; bone marrow; lymph; adrenal gland; thyroid; bone; pharynx; ascites; pituitary gland; esophagus; stomach; heart; larynx; nerve; adipose tissue; pineal gland
MAPPING POSITION
Genomic location specified by transcript mapping, radiation hybrid mapping, genetic mapping or cytogenetic mapping.
Chromosome: 22
Map position: 22q12.2
UniSTS entry: Chr 22 D22S1559
UniSTS entry: Chr 22 RH17805
UniSTS entry: Chr 22 RH78161 [Map Viewer]
UniSTS entry: Chr 22 STS-X85237
UniSTS entry: Chr 22 STS-W73688
UniSTS entry: Chr 22 WI-10121
UniSTS entry: RH11231
SEQUENCES
Sequences representing this gene; mRNAs, ESTs, and gene predictions supported by transcribed sequences.

mRNA sequences (8)

NM_005877.4 Homo sapiens splicing factor 3a, subunit 1, 120kDa (SF3A1), transcript variant 1, mRNA PA
BC001976.1 Homo sapiens splicing factor 3a, subunit 1, 120kDa, mRNA (cDNA clone MGC:5589 IMAGE:3459964), complete cds PA
CR456575.1 Homo sapiens SF3A1 full length open reading frame (ORF) cDNA clone (cDNA clone C22ORF:pGEM.SF3A1) P
NM_001005409.1 Homo sapiens splicing factor 3a, subunit 1, 120kDa (SF3A1), transcript variant 2, mRNA PA
BC007684.2 Homo sapiens splicing factor 3a, subunit 1, 120kDa, mRNA (cDNA clone MGC:3569 IMAGE:3634035), complete cds PA
AK098463.1 Homo sapiens cDNA FLJ25597 fis, clone JTH13437, highly similar to SPLICEOSOME ASSOCIATED PROTEIN 114 P
AK303273.1 Homo sapiens cDNA FLJ55438 complete cds, highly similar to Splicing factor 3 subunit 1 P
X85237.1 H.sapiens mRNA for splicing factor SF3a120 P

EST sequences (10 of 1232) [Show all sequences]

AA864443.1 Clone IMAGE:1456558 kidney 3' read
AA903247.1 Clone IMAGE:1517270 uncharacterized tissue 3' read
AA970784.1 Clone IMAGE:1560819 mixed 3' read A
R15805.1 Clone IMAGE:53305 brain 3' read A
AA974470.1 Clone IMAGE:1372110 lymph node 3' read A
AA977303.1 Clone IMAGE:1589986 kidney 3' read
R14997.1 Clone IMAGE:35517 brain 5' read
AA908214.1 Clone IMAGE:1522579 lung 3' read A
R17376.1 Clone IMAGE:30854 brain 5' read
R17412.1 Clone IMAGE:30974 brain 5' read


Key to Symbols

P Has similarity to known Proteins (after translation)
A Contains a poly-Adenylation signal
S Sequence is a Suboptimal member of this cluster
M Clone is putatively CDS-complete by MGC criteria

 
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