> Alcohol dehydrogenase 1B (class I), beta polypeptide (ADH1B)
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UGID:130646     UniGene Hs.4     Homo sapiens (human)   ADH1B
Alcohol dehydrogenase 1B (class I), beta polypeptide (ADH1B)

Human protein-coding gene ADH1B. Represented by 955 ESTs from 145 cDNA libraries. Corresponds to reference sequence NM_000668.4. [UniGene 130646 - Hs.4]

SELECTED PROTEIN SIMILARITIES
Comparison of cluster transcripts with RefSeq proteins. The alignments can suggest function of the cluster.
Best Hits and Hits from model organismsSpeciesId(%)Len(aa)
NP_001029330.1 ADH1B gene product P. troglodytes 100.0 374
NP_000659.2 ADH1B gene product H. sapiens 100.0 374
NP_031435.1 Adh1 gene product M. musculus 88.8 374
NP_001086118.1 MGC83376 protein X. laevis 71.7 374
NP_571924.2 adh5 gene product D. rerio 66.2 375
XP_001693934.1 formaldehyde dehydrogenase C. reinhardtii 62.1 376
NP_524310.1 formaldehyde dehydrogenase D. melanogaster 57.3 378
NP_199207.1 alcohol dehydrogenase class-3 A. thaliana 57.1 375
XP_960697.1 S-(hydroxymethyl)glutathione dehydrogenase N. crassa 55.2 375
NP_741507.1 Protein H24K24.3, isoform a C. elegans 55.1 379
NP_010113.1 bifunctional alcohol dehydrogenase/S-(hydroxymethyl)glutathione dehydrogenase S. cerevisiae 50.3 380
Other hits (2 of 62) [Show all]SpeciesId(%)Len(aa)
XP_001106834.1 PREDICTED: alcohol dehydrogenase 1B isoform 3 M. mulatta 98.4 374
XP_003899049.1 PREDICTED: alcohol dehydrogenase 1C P. anubis 96.8 374

GENE EXPRESSION
Tissues and development stages from this gene's sequences survey gene expression. Links to other NCBI expression resources.
EST Profile: Approximate expression patterns inferred from EST sources.
[Show more entries with profiles like this]
GEO Profiles: Experimental gene expression data (Gene Expression Omnibus).
cDNA Sources: liver; trachea; mammary gland; adipose tissue; uterus; lung; heart; intestine; brain; adrenal gland; spleen; stomach; cervix; muscle; esophagus; mouth; uncharacterized tissue; kidney; mixed; connective tissue; testis; thymus; nerve; vascular; pharynx; pancreas; prostate; eye; bladder; skin; placenta; larynx; ganglia; embryonic tissue
MAPPING POSITION
Genomic location specified by transcript mapping, radiation hybrid mapping, genetic mapping or cytogenetic mapping.
Chromosome: 4
Map position: 4q23
UniSTS entry: Chr 4 D4S2817 [Map Viewer]
UniSTS entry: Chr 4 GDB:187387
UniSTS entry: Chr 4 G60286
UniSTS entry: Chr 4 SHGC-50678
UniSTS entry: Chr 19 SGC31874 [Map Viewer]
UniSTS entry: Chr 4 SHGC-35417 [Map Viewer]
UniSTS entry: Chr 4 ADH1B_V67
UniSTS entry: Chr 1 D10S16
UniSTS entry: Chr 4 SHGC-59546 [Map Viewer]
SEQUENCES
Sequences representing this gene; mRNAs, ESTs, and gene predictions supported by transcribed sequences.

mRNA sequences (13)

NM_000668.4 Homo sapiens alcohol dehydrogenase 1B (class I), beta polypeptide (ADH1B), mRNA P
M21692.1 Human class I alcohol dehydrogenase (ADH2) beta-1 subunit mRNA, complete cds P
M24317.1 Human class I alcohol dehydrogenase (ADH2) beta-1 subunit mRNA, complete cds P
AF153821.1 Homo sapiens alcohol dehydrogenase beta2 subunit mRNA, complete cds PA
AK311712.1 Homo sapiens cDNA, FLJ18754 A
X03350.1 Human mRNA for alcohol dehydrogenase beta-1-subunit (ADH1-2 allele) P
BC033009.2 Homo sapiens alcohol dehydrogenase 1B (class I), beta polypeptide, mRNA (cDNA clone MGC:26565 IMAGE:4828235), complete cds PA
AK301018.1 Homo sapiens cDNA FLJ51963 complete cds, highly similar to Alcohol dehydrogenase 1B (EC 1.1.1.1) P
AK299409.1 Homo sapiens cDNA FLJ51682 complete cds, highly similar to Alcohol dehydrogenase 1B (EC 1.1.1.1) P
AK304396.1 Homo sapiens cDNA FLJ52054 complete cds, highly similar to Alcohol dehydrogenase 1B (EC 1.1.1.1) P
AK303945.1 Homo sapiens cDNA FLJ52389 complete cds, highly similar to Alcohol dehydrogenase 1B (EC 1.1.1.1) P
AK316501.1 Homo sapiens cDNA, FLJ79400 complete cds, highly similar to Alcohol dehydrogenase 1B (EC 1.1.1.1) P
D00137.1 Homo sapiens mRNA for alcohol dehydrogenase beta 1, complete cds P

EST sequences (10 of 955) [Show all sequences]

AI000973.1 Clone IMAGE:1609547 mammary gland 3' read A
AA903791.1 Clone IMAGE:1517908 uncharacterized tissue 3' read A
AI141127.1 Clone IMAGE:1739426 lung 3' read A
BX099744.1 Clone IMAGp998M241063_;_IMAGE:450623 mixed
AI185554.1 Clone IMAGE:1742832 lung 3' read
AI253640.1 Clone IMAGE:2032617 prostate 3' read
AI262943.1 Clone IMAGE:2028770 kidney 3' read
CB148959.1 Clone L17N670205-1-A08 liver 5' read
CB148965.1 Clone L17N670205-1-B06 liver 5' read P
CB154096.1 Clone L17N670205-3-C03 liver 5' read A


Key to Symbols

P Has similarity to known Proteins (after translation)
A Contains a poly-Adenylation signal
S Sequence is a Suboptimal member of this cluster
M Clone is putatively CDS-complete by MGC criteria

 
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