CDC42 effector protein (Rho GTPase binding) 4 (CDC42EP4)

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UGID:131464 UniGene Hs.3903 Homo sapiens (human) CDC42EP4

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CDC42 effector protein (Rho GTPase binding) 4 (CDC42EP4)

Human protein-coding gene CDC42EP4. Represented by 1081 ESTs from 226 cDNA libraries. Corresponds to reference sequence NM_012121.4. [UniGene 131464 - Hs.3903]

SELECTED PROTEIN SIMILARITIES

Comparison of cluster transcripts with RefSeq proteins. The alignments can suggest function of the cluster.

Best Hits and Hits from model organisms		Species	Id(%)	Len(aa)
NP_036253.2 Conserved domains (CDD) Gene summary Protein sequence Protein/EST matches (ProtEST) Protein/protein matches (BLink)	CDC42EP4 gene product	H. sapiens	100.0	355
NP_001156818.1 Conserved domains (CDD) Gene summary Protein sequence Protein/EST matches (ProtEST) Protein/protein matches (BLink)	Cdc42ep4 gene product	M. musculus	85.4	348
NP_001084868.1 Conserved domains (CDD) Gene summary Protein sequence Protein/EST matches (ProtEST) Protein/protein matches (BLink)	uncharacterized protein LOC431917	X. laevis	65.3	299
XP_003199689.1 Conserved domains (CDD) Gene summary Protein sequence Protein/EST matches (ProtEST) Protein/protein matches (BLink)	PREDICTED: cdc42 effector protein 4-like	D. rerio	60.1	335
Other hits (2 of 20) [Show all]		Species	Id(%)	Len(aa)
XP_001167847.1 Conserved domains (CDD) Gene summary Protein sequence Protein/EST matches (ProtEST) Protein/protein matches (BLink)	PREDICTED: cdc42 effector protein 4 isoform 1	P. troglodytes	99.2	355
XP_003913416.1 Conserved domains (CDD) Gene summary Protein sequence Protein/EST matches (ProtEST) Protein/protein matches (BLink)	PREDICTED: cdc42 effector protein 4 isoform 1	P. anubis	98.6	355

GENE EXPRESSION

Tissues and development stages from this gene's sequences survey gene expression. Links to other NCBI expression resources.

	EST Profile:	Approximate expression patterns inferred from EST sources. [Show more entries with profiles like this]
	GEO Profiles:	Experimental gene expression data (Gene Expression Omnibus).
	cDNA Sources:	brain; pancreas; testis; mouth; thymus; placenta; lung; mammary gland; kidney; uterus; embryonic tissue; trachea; vascular; eye; prostate; spleen; skin; esophagus; connective tissue; uncharacterized tissue; mixed; ovary; heart; stomach; muscle; intestine; bladder; cervix; adrenal gland; liver; nerve; pineal gland; ascites; bone; thyroid; blood; parathyroid; ganglia

MAPPING POSITION

Genomic location specified by transcript mapping, radiation hybrid mapping, genetic mapping or cytogenetic mapping.

Chromosome:	17
Map position:	17q24-q25
UniSTS entry:	Chr 17	RH121912
UniSTS entry:	Chr 3	A002D24
UniSTS entry:	Chr 17	G19982

SEQUENCES

Sequences representing this gene; mRNAs, ESTs, and gene predictions supported by transcribed sequences.

mRNA sequences (9)

AF099664.1	Homo sapiens Cdc42 effector protein 4 mRNA, complete cds	P
NM_012121.4	Homo sapiens CDC42 effector protein (Rho GTPase binding) 4 (CDC42EP4), mRNA	PA
BC002774.1	Homo sapiens CDC42 effector protein (Rho GTPase binding) 4, mRNA (cDNA clone MGC:3740 IMAGE:3617435), complete cds	PA
AL162074.1	Homo sapiens mRNA; cDNA DKFZp762L106 (from clone DKFZp762L106)	A
AB042237.1	Homo sapiens Borg4 mRNA, complete cds	PA
AK027385.1	Homo sapiens cDNA FLJ14479 fis, clone MAMMA1002143, highly similar to Cdc42 effector protein 4 (Binder of Rho GTPases 4)	PA
BC010451.1	Homo sapiens CDC42 effector protein (Rho GTPase binding) 4, mRNA (cDNA clone MGC:17125 IMAGE:4181539), complete cds	PA
AK312536.1	Homo sapiens cDNA, FLJ92905, Homo sapiens CDC42 effector protein (Rho GTPase binding) 4(CDC42EP4), mRNA	P
AK097835.1	Homo sapiens cDNA FLJ40516 fis, clone TESTI2046569, highly similar to Cdc42 effector protein 4 (Binder of RhoGTPases 4)	P

EST sequences (10 of 1081) [Show all sequences]

AA991278.1	Clone IMAGE:1608852	mammary gland	3' read	A
AA991280.1	Clone IMAGE:1608856	mammary gland	3' read	A
AI039957.1	Clone IMAGE:1659714	embryonic tissue	3' read	A
AI049895.1	Clone IMAGE:1700201	kidney	3' read	A
AI094972.1	Clone IMAGE:1686311	brain	3' read	A
AI140110.1	Clone IMAGE:1694498	heart	3' read	A
AI143750.1	Clone IMAGE:1705963	heart	3' read	A
T06431.1	Clone HFBDT35	brain
AI186166.1	Clone IMAGE:1742026	lung	3' read	A
AI268792.1	Clone IMAGE:1911020	lung	3' read	A

Key to Symbols

P Has similarity to known Proteins (after translation)
A Contains a poly-Adenylation signal
S Sequence is a Suboptimal member of this cluster
M Clone is putatively CDS-complete by MGC criteria