> X-ray repair complementing defective repair in Chinese hamster cells 5 (double-strand-break rejoining) (XRCC5)
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UGID:207432     UniGene Hs.388739     Homo sapiens (human)   XRCC5 Order cDNA clone, Links
X-ray repair complementing defective repair in Chinese hamster cells 5 (double-strand-break rejoining) (XRCC5)

Human protein-coding gene XRCC5. Represented by 2547 ESTs from 568 cDNA libraries. Corresponds to reference sequence NM_021141.3. [UniGene 207432 - Hs.388739]

SELECTED PROTEIN SIMILARITIES
Comparison of cluster transcripts with RefSeq proteins. The alignments can suggest function of the cluster.
Best Hits and Hits from model organismsSpeciesId(%)Len(aa)
NP_066964.1 XRCC5 gene product H. sapiens 100.0 731
XP_001151873.2 PREDICTED: X-ray repair cross-complementing protein 5 isoform 7 P. troglodytes 99.9 826
NP_001244295.1 X-ray repair cross-complementing protein 5 M. mulatta 99.7 731
XP_003919748.1 PREDICTED: LOW QUALITY PROTEIN: X-ray repair cross-complementing protein 5 P. anubis 99.7 617
NP_033559.2 Xrcc5 gene product M. musculus 85.2 731
NP_001081127.1 X-ray repair complementing defective repair in Chinese hamster cells 5 X. laevis 72.7 725
NP_001017360.1 xrcc5 gene product D. rerio 68.5 726
Other hits (2 of 20) [Show all]SpeciesId(%)Len(aa)
XP_002712509.1 PREDICTED: ATP-dependent DNA helicase II O. cuniculus 88.7 732
XP_003133697.2 PREDICTED: X-ray repair cross-complementing protein 5 S. scrofa 87.5 732

GENE EXPRESSION
Tissues and development stages from this gene's sequences survey gene expression. Links to other NCBI expression resources.
EST Profile: Approximate expression patterns inferred from EST sources.
[Show more entries with profiles like this]
GEO Profiles: Experimental gene expression data (Gene Expression Omnibus).
cDNA Sources: brain; testis; embryonic tissue; uncharacterized tissue; skin; liver; uterus; placenta; lung; kidney; eye; mixed; blood; prostate; intestine; connective tissue; mammary gland; trachea; spleen; thymus; mouth; bone; ovary; heart; pancreas; cervix; vascular; muscle; stomach; pharynx; thyroid; bone marrow; lymph node; ascites; tonsil; bladder; umbilical cord; parathyroid; larynx; esophagus; nerve; pituitary gland; adrenal gland; lymph; amniotic fluid; salivary gland; ganglia; adipose tissue; epididymis; ear; peritoneum; pineal gland
MAPPING POSITION
Genomic location specified by transcript mapping, radiation hybrid mapping, genetic mapping or cytogenetic mapping.
Chromosome: 2
Map position: 2q35
UniSTS entry: Chr 2 D2S2606 [Map Viewer]
UniSTS entry: Chr 2 SHGC-11966 [Map Viewer]
UniSTS entry: Chr 2 XRCC5_1894
UniSTS entry: Chr 2 HSC2AF082 [Map Viewer]
UniSTS entry: G31045
UniSTS entry: Chr 2 G67231
SEQUENCES
Sequences representing this gene; mRNAs, ESTs, and gene predictions supported by transcribed sequences.

mRNA sequences (12)

M30938.1 Human Ku (p70/p80) subunit mRNA, complete cds P
BX647578.1 Homo sapiens mRNA; cDNA DKFZp313C1230 (from clone DKFZp313C1230) A
AK222603.1 Homo sapiens mRNA for ATP-dependent DNA helicase II variant, clone: CAS09969 P
BC095442.1 Homo sapiens X-ray repair complementing defective repair in Chinese hamster cells 5 (double-strand-break rejoining), mRNA (cDNA clone MGC:111164 IMAGE:30329657), complete cds PA
AK023296.1 Homo sapiens cDNA FLJ13234 fis, clone OVARC1000302
AK026166.1 Homo sapiens cDNA: FLJ22513 fis, clone HRC12111, highly similar to HUMKUP Human Ku (p70/p80) subunit mRNA PA
J04977.1 Human Ku autoimmune antigen gene, complete cds P
NM_021141.3 Homo sapiens X-ray repair complementing defective repair in Chinese hamster cells 5 (double-strand-break rejoining) (XRCC5), mRNA PA
X57500.1 H.sapiens mRNA for nuclear factor IV P
BC019027.2 Homo sapiens X-ray repair complementing defective repair in Chinese hamster cells 5 (double-strand-break rejoining), mRNA (cDNA clone MGC:20677 IMAGE:4555162), complete cds PA
AK290740.1 Homo sapiens cDNA FLJ75456 complete cds, highly similar to Homo sapiens X-ray repair complementing defective repair in Chinese hamster cells 5 (double-strand-break rejoining; Ku autoantigen, 80kDa) (XRCC5), mRNA P
AK096408.1 Homo sapiens cDNA FLJ39089 fis, clone NT2RP7019401, highly similar to ATP-DEPENDENT DNA HELICASE II, 80 KDA SUBUNIT P

EST sequences (10 of 2547) [Show all sequences]

AA922404.1 Clone IMAGE:1486367 mouth 3' read
AA973852.1 Clone IMAGE:1586084 uncharacterized tissue 3' read
AA974862.1 Clone IMAGE:1567745 lung 3' read
R14642.1 Clone IMAGE:35510 brain 5' read P
AA902464.1 Clone IMAGE:1519350 uncharacterized tissue 3' read
R17102.1 Clone IMAGE:26595 brain 5' read P
AA906518.1 Clone IMAGE:1506884 mixed 3' read A
AA907178.1 Clone IMAGE:1521888 lung 3' read
AI004332.1 Clone IMAGE:1631867 mammary gland 3' read PA
AI016390.1 Clone IMAGE:1641670 testis 3' read A


Key to Symbols

P Has similarity to known Proteins (after translation)
A Contains a poly-Adenylation signal
S Sequence is a Suboptimal member of this cluster
M Clone is putatively CDS-complete by MGC criteria

 
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