> Dishevelled, dsh homolog 3 (Drosophila) (DVL3)
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UGID:207074     UniGene Hs.388116     Homo sapiens (human)   DVL3 Order cDNA clone, Links
Dishevelled, dsh homolog 3 (Drosophila) (DVL3)

Human protein-coding gene DVL3. Represented by 431 ESTs from 237 cDNA libraries. Corresponds to reference sequence NM_004423.3. [UniGene 207074 - Hs.388116]

SELECTED PROTEIN SIMILARITIES
Comparison of cluster transcripts with RefSeq proteins. The alignments can suggest function of the cluster.
Best Hits and Hits from model organismsSpeciesId(%)Len(aa)
XP_003894801.1 PREDICTED: segment polarity protein dishevelled homolog DVL-3 isoform 1 P. anubis 100.0 715
XP_516908.3 PREDICTED: segment polarity protein dishevelled homolog DVL-3 isoform 8 P. troglodytes 100.0 715
NP_004414.3 DVL3 gene product H. sapiens 100.0 715
XP_002802939.1 PREDICTED: segment polarity protein dishevelled homolog DVL-3-like M. mulatta 100.0 502
XP_002684923.1 PREDICTED: LOW QUALITY PROTEIN: segment polarity protein dishevelled homolog DVL-3 B. taurus 99.9 716
XP_535822.2 PREDICTED: segment polarity protein dishevelled homolog DVL-3 isoform 1 C. lupus familiaris 99.9 715
XP_003358783.1 PREDICTED: segment polarity protein dishevelled homolog DVL-3, partial S. scrofa 99.8 661
NP_031915.2 Dvl3 gene product M. musculus 99.7 715
NP_001100551.1 segment polarity protein dishevelled homolog DVL-3 R. norvegicus 99.5 667
NP_001086098.1 segment polarity protein dishevelled homolog DVL-3 X. laevis 91.4 711
XP_001920242.3 PREDICTED: segment polarity protein dishevelled homolog DVL-3-like D. rerio 89.2 705
NP_511118.2 dishevelled D. melanogaster 60.0 603
NP_494980.3 Protein DSH-1, isoform b C. elegans 56.5 375
Other hits (2 of 29) [Show all]SpeciesId(%)Len(aa)
XP_004003880.1 PREDICTED: segment polarity protein dishevelled homolog DVL-3 O. aries 99.1 656
XP_001374509.1 PREDICTED: segment polarity protein dishevelled homolog DVL-3-like M. domestica 97.5 632

GENE EXPRESSION
Tissues and development stages from this gene's sequences survey gene expression. Links to other NCBI expression resources.
EST Profile: Approximate expression patterns inferred from EST sources.
[Show more entries with profiles like this]
GEO Profiles: Experimental gene expression data (Gene Expression Omnibus).
cDNA Sources: brain; intestine; placenta; mixed; skin; lung; eye; pancreas; testis; thyroid; uterus; mammary gland; embryonic tissue; prostate; uncharacterized tissue; ovary; bone marrow; cervix; connective tissue; lymph node; mouth; pharynx; stomach; bone; kidney; larynx; heart; blood; epididymis; ascites; adrenal gland; ganglia; nerve
MAPPING POSITION
Genomic location specified by transcript mapping, radiation hybrid mapping, genetic mapping or cytogenetic mapping.
Chromosome: 3
Map position: 3q27
UniSTS entry: Chr 3 RH101840
UniSTS entry: Chr 3 SHGC-77602 [Map Viewer]
UniSTS entry: Chr 3 STS-R80399
UniSTS entry: Chr 3 Dvl3
UniSTS entry: Chr 3 D3S4388
UniSTS entry: Dvl3
UniSTS entry: Chr 3 RH77956
UniSTS entry: Chr 12 RH66958
UniSTS entry: Chr 12 G32288
SEQUENCES
Sequences representing this gene; mRNAs, ESTs, and gene predictions supported by transcribed sequences.

mRNA sequences (11)

AL110278.1 Homo sapiens mRNA; cDNA DKFZp586M1622 (from clone DKFZp586M1622); partial cds PA
NM_004423.3 Homo sapiens dishevelled, dsh homolog 3 (Drosophila) (DVL3), mRNA P
U48252.1 Human protein kinase C-binding protein RACK8 mRNA, partial cds P
U49262.1 Human dishevelled (DVL) mRNA, complete cds P
BC018289.1 Homo sapiens, clone IMAGE:3454067, mRNA, partial cds PA
BC032459.1 Homo sapiens dishevelled, dsh homolog 3 (Drosophila), mRNA (cDNA clone MGC:40316 IMAGE:5200610), complete cds PA
AK093469.1 Homo sapiens cDNA FLJ36150 fis, clone TESTI2025269, highly similar to SEGMENT POLARITY PROTEIN DISHEVELLED HOMOLOG DVL-3 P
AK304686.1 Homo sapiens cDNA FLJ61571 complete cds, highly similar to Segment polarity protein dishevelled homolog DVL-3 PA
D86963.1 Homo sapiens mRNA for KIAA0208 gene, partial cds P
U75651.1 Human dishevelled 3 (DVL3) mRNA, complete cds P
AF006013.1 Homo sapiens dishevelled 3 (DVL3) mRNA, complete cds P

EST sequences (10 of 431) [Show all sequences]

T05734.1 Clone HFBDF61 brain
AI014586.1 Clone IMAGE:1628734 mixed 3' read A
AI041735.1 Clone IMAGE:1660420 mixed 3' read P
CB044097.1 Clone IMAGE:3217619 intestine 3' read A
CB044098.1 Clone IMAGE:3217619 intestine 5' read
BX095066.1 Clone IMAGp998J20255_;_IMAGE:159475 mammary gland PA
AI220395.1 Clone IMAGE:1840865 mixed 3' read
AI221788.1 Clone IMAGE:1843293 mixed 3' read A
AI266319.1 Clone IMAGE:1927624 lung 3' read A
AI270784.1 Clone IMAGE:1964015 ovary 3' read A


Key to Symbols

P Has similarity to known Proteins (after translation)
A Contains a poly-Adenylation signal
S Sequence is a Suboptimal member of this cluster
M Clone is putatively CDS-complete by MGC criteria

 
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