> Poly(A) binding protein, cytoplasmic 1 (PABPC1)
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UGID:206887     UniGene Hs.387804     Homo sapiens (human)   PABPC1 Order cDNA clone, Links
Poly(A) binding protein, cytoplasmic 1 (PABPC1)

Human protein-coding gene PABPC1. Represented by 3606 ESTs from 800 cDNA libraries. Corresponds to reference sequence NM_002568.3. [UniGene 206887 - Hs.387804]

SELECTED PROTEIN SIMILARITIES
Comparison of cluster transcripts with RefSeq proteins. The alignments can suggest function of the cluster.
Best Hits and Hits from model organismsSpeciesId(%)Len(aa)
NP_032800.2 Pabpc1 gene product M. musculus 100.0 635
XP_001098239.1 PREDICTED: polyadenylate-binding protein 1 isoform 2 M. mulatta 100.0 635
XP_003903080.1 PREDICTED: polyadenylate-binding protein 1 P. anubis 100.0 635
NP_002559.2 PABPC1 gene product H. sapiens 100.0 635
XP_856708.1 PREDICTED: polyadenylate-binding protein 1 isoform 6 C. lupus familiaris 100.0 635
XP_001927782.1 PREDICTED: polyadenylate-binding protein 1 S. scrofa 100.0 635
NP_776993.1 PABPC1 gene product B. taurus 100.0 635
XP_002710763.1 PREDICTED: poly A binding protein, cytoplasmic 4 O. cuniculus 100.0 635
XP_004012050.1 PREDICTED: polyadenylate-binding protein 1 O. aries 100.0 571
XP_001492678.3 PREDICTED: polyadenylate-binding protein 1 E. caballus 100.0 564
NP_599180.1 Pabpc1 gene product R. norvegicus 99.8 635
XP_003226647.1 PREDICTED: polyadenylate-binding protein 1-like A. carolinensis 99.7 635
NP_001085069.1 polyadenylate-binding protein 1-B X. laevis 97.8 632
NP_957176.1 pabpc1b gene product D. rerio 97.0 633
NP_476667.1 polyA-binding protein, isoform A D. melanogaster 71.9 633
NP_001021709.1 Protein PAB-1, isoform a C. elegans 67.9 639
NP_011092.1 Pab1p S. cerevisiae 62.1 536
XP_960425.1 polyadenylate-binding protein N. crassa 62.0 534
XP_001689671.1 polyadenylate-binding protein RB47 C. reinhardtii 60.2 635
NP_564554.1 poly(A) binding protein 8 A. thaliana 58.7 664
Other hits (2 of 52) [Show all]SpeciesId(%)Len(aa)
XP_002200268.1 PREDICTED: polyadenylate-binding protein 1 T. guttata 99.4 636
NP_001026768.1 PABPC1 gene product G. gallus 99.4 636

GENE EXPRESSION
Tissues and development stages from this gene's sequences survey gene expression. Links to other NCBI expression resources.
EST Profile: Approximate expression patterns inferred from EST sources.
[Show more entries with profiles like this]
GEO Profiles: Experimental gene expression data (Gene Expression Omnibus).
cDNA Sources: intestine; uncharacterized tissue; brain; mammary gland; embryonic tissue; mixed; testis; skin; eye; prostate; uterus; lung; stomach; pancreas; liver; blood; bone; kidney; larynx; connective tissue; lymph node; ovary; placenta; bone marrow; pharynx; ascites; vascular; bladder; thyroid; cervix; mouth; muscle; lymph; ear; heart; tonsil; salivary gland; adrenal gland; thymus; spleen; esophagus; epididymis; trachea; nerve; pituitary gland; amniotic fluid; adipose tissue; ganglia; umbilical cord; parathyroid
MAPPING POSITION
Genomic location specified by transcript mapping, radiation hybrid mapping, genetic mapping or cytogenetic mapping.
Chromosome: 8
Map position: 8q22.2-q23
UniSTS entry: Chr 8 G49185
UniSTS entry: Chr 8 GDB:568589
UniSTS entry: PABPC1
UniSTS entry: Chr 8 MARC_1283-1284:991931128:1
UniSTS entry: Chr 13 SHGC-30876
UniSTS entry: Chr 8 D13S1095E
UniSTS entry: Pabpc1
UniSTS entry: Pabpc2
UniSTS entry: Pabpc1
UniSTS entry: Chr 8 STS-R77214 [Map Viewer]
SEQUENCES
Sequences representing this gene; mRNAs, ESTs, and gene predictions supported by transcribed sequences.

mRNA sequences (10)

AK130523.1 Homo sapiens cDNA FLJ27013 fis, clone SLV05396, highly similar to Polyadenylate-binding protein 1 P
NM_002568.3 Homo sapiens poly(A) binding protein, cytoplasmic 1 (PABPC1), mRNA PA
AK057080.1 Homo sapiens cDNA FLJ32518 fis, clone SMINT1000118
BC015958.2 Homo sapiens poly(A) binding protein, cytoplasmic 1, mRNA (cDNA clone MGC:15290 IMAGE:3940309), complete cds PA
AK298990.1 Homo sapiens cDNA FLJ59219 complete cds, highly similar to Poly(A)-binding protein 1 P
AK303120.1 Homo sapiens cDNA FLJ57246 complete cds, highly similar to Poly(A)-binding protein 1 P
BC023217.1 Homo sapiens cDNA clone IMAGE:4522410 PA
Z48501.1 H.sapiens mRNA for polyadenylate binding protein II P
Y00345.1 Human mRNA for polyA binding protein P
BC023520.2 Homo sapiens poly(A) binding protein, cytoplasmic 1, mRNA (cDNA clone MGC:12727 IMAGE:4123269), complete cds PA

EST sequences (10 of 3606) [Show all sequences]

AA961112.1 Clone IMAGE:1569807 lung 3' read A
AA962698.1 Clone IMAGE:1575469 intestine 3' read
AA971022.1 Clone IMAGE:1582045 mixed 3' read A
AA978233.1 Clone IMAGE:1273938 bone
AA987995.1 Clone IMAGE:1604387 lung 3' read A
AA988483.1 Clone IMAGE:1603007 lung 3' read A
R16426.1 Clone IMAGE:129325 mixed 5' read P
AI015336.1 Clone IMAGE:1618790 testis 3' read A
AI022806.1 Clone IMAGE:1650760 parathyroid 3' read
R18798.1 Clone IMAGE:27347 brain 5' read P


Key to Symbols

P Has similarity to known Proteins (after translation)
A Contains a poly-Adenylation signal
S Sequence is a Suboptimal member of this cluster
M Clone is putatively CDS-complete by MGC criteria

 
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