> Palmitoyl-protein thioesterase 1 (PPT1)
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UGID:131461     UniGene Hs.3873     Homo sapiens (human)   PPT1
Palmitoyl-protein thioesterase 1 (PPT1)

Human protein-coding gene PPT1. Represented by 1879 ESTs from 420 cDNA libraries. Corresponds to 2 reference sequences (different isoforms). [UniGene 131461 - Hs.3873]

SELECTED PROTEIN SIMILARITIES
Comparison of cluster transcripts with RefSeq proteins. The alignments can suggest function of the cluster.
Best Hits and Hits from model organismsSpeciesId(%)Len(aa)
NP_000301.1 PPT1 gene product H. sapiens 100.0 305
XP_001082462.1 PREDICTED: palmitoyl-protein thioesterase 1 isoform 3 M. mulatta 99.7 305
XP_003891698.1 PREDICTED: palmitoyl-protein thioesterase 1 P. anubis 99.7 305
XP_001172215.1 PREDICTED: palmitoyl-protein thioesterase 1 isoform 4 P. troglodytes 99.7 305
NP_032943.2 Ppt1 gene product M. musculus 90.8 305
NP_998504.1 ppt1 gene product D. rerio 79.1 302
NP_001091368.1 palmitoyl-protein thioesterase 1 precursor X. laevis 78.5 298
NP_504684.1 Palmitoyl Protein Thioesterase family member (ppt-1) C. elegans 60.0 269
NP_727284.1 Palmitoyl-protein thioesterase 1 D. melanogaster 59.5 311
XP_001698944.1 hypothetical protein CHLREDRAFT_131913 C. reinhardtii 46.4 267
Other hits (2 of 38) [Show all]SpeciesId(%)Len(aa)
XP_004001885.1 PREDICTED: palmitoyl-protein thioesterase 1 isoform 1 O. aries 96.1 305
NP_001010944.1 PPT1 gene product C. lupus familiaris 95.8 305

GENE EXPRESSION
Tissues and development stages from this gene's sequences survey gene expression. Links to other NCBI expression resources.
EST Profile: Approximate expression patterns inferred from EST sources.
[Show more entries with profiles like this]
GEO Profiles: Experimental gene expression data (Gene Expression Omnibus).
cDNA Sources: brain; testis; mammary gland; uncharacterized tissue; blood; lung; kidney; spleen; uterus; skin; pharynx; intestine; placenta; pancreas; eye; connective tissue; prostate; embryonic tissue; mouth; liver; ovary; thymus; esophagus; bladder; spinal cord; vascular; stomach; muscle; cervix; adrenal gland; ascites; mixed; trachea; salivary gland; thyroid; bone marrow; heart; bone; lymph node; lymph; umbilical cord; ear; nerve; parathyroid; pituitary gland; ganglia; adipose tissue
MAPPING POSITION
Genomic location specified by transcript mapping, radiation hybrid mapping, genetic mapping or cytogenetic mapping.
Chromosome: 1
Map position: 1p32
UniSTS entry: Chr 1 WI-12268 [Map Viewer]
UniSTS entry: Chr 1 D1S1857E [Map Viewer]
UniSTS entry: Chr 1 A006O26
SEQUENCES
Sequences representing this gene; mRNAs, ESTs, and gene predictions supported by transcribed sequences.

mRNA sequences (10)

NM_000310.3 Homo sapiens palmitoyl-protein thioesterase 1 (PPT1), transcript variant 1, mRNA PA
CR542053.1 Homo sapiens full open reading frame cDNA clone RZPDo834A0836D for gene PPT1, palmitoyl-protein thioesterase 1 (ceroid-lipofuscinosis, neuronal 1, infantile); complete cds, without stopcodon P
BC008426.1 Homo sapiens palmitoyl-protein thioesterase 1, mRNA (cDNA clone MGC:14590 IMAGE:4249991), complete cds PA
U44772.1 Human palmitoyl protein thioesterase mRNA, complete cds P
AK310799.1 Homo sapiens cDNA, FLJ17841 P
AK312287.1 Homo sapiens cDNA, FLJ92589, Homo sapiens palmitoyl-protein thioesterase 1(ceroid-lipofuscinosis, neuronal 1, infantile) (PPT1), mRNA P
AK301682.1 Homo sapiens cDNA FLJ53673 complete cds, highly similar to Palmitoyl-protein thioesterase 1 precursor (EC 3.1.2.22) P
AK302232.1 Homo sapiens cDNA FLJ53679 complete cds, highly similar to Palmitoyl-protein thioesterase 1 precursor (EC 3.1.2.22) P
AK075496.1 Homo sapiens cDNA PSEC0193 fis, clone HEMBA1000760, highly similar to Homo sapiens palmitoyl-protein thioesterase (PPT) gene P
NM_001142604.1 Homo sapiens palmitoyl-protein thioesterase 1 (PPT1), transcript variant 2, mRNA PA

EST sequences (10 of 1879) [Show all sequences]

R14281.1 Clone IMAGE:28552 brain 5' read
AA985646.1 Clone IMAGE:1601278 lung 3' read A
AA993082.1 Clone IMAGE:1625031 embryonic tissue 3' read A
AI015556.1 Clone IMAGE:1636091 kidney 3' read A
AI051902.1 Clone IMAGE:1649046 parathyroid 3' read A
AI091599.1 Clone IMAGE:1682967 parathyroid 3' read A
CB054902.1 Clone IMAGE:3291869 brain 3' read A
AI159896.1 Clone IMAGE:1704051 brain 3' read A
BX115398.1 Clone IMAGp998O1275_;_IMAGE:24177 brain A
AI192174.1 Clone IMAGE:1722039 uterus 3' read A


Key to Symbols

P Has similarity to known Proteins (after translation)
A Contains a poly-Adenylation signal
S Sequence is a Suboptimal member of this cluster
M Clone is putatively CDS-complete by MGC criteria

 
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