> Serpin peptidase inhibitor, clade G (C1 inhibitor), member 1 (SERPING1)
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UGID:205060     UniGene Hs.384598     Homo sapiens (human)   SERPING1 Order cDNA clone, Links
Serpin peptidase inhibitor, clade G (C1 inhibitor), member 1 (SERPING1)

Human protein-coding gene SERPING1. Represented by 1620 ESTs from 366 cDNA libraries. Corresponds to 2 reference sequences (different isoforms). [UniGene 205060 - Hs.384598]

SELECTED PROTEIN SIMILARITIES
Comparison of cluster transcripts with RefSeq proteins. The alignments can suggest function of the cluster.
Best Hits and Hits from model organismsSpeciesId(%)Len(aa)
NP_000053.2 SERPING1 gene product H. sapiens 100.0 499
XP_001159926.1 PREDICTED: plasma protease C1 inhibitor isoform 1 P. troglodytes 99.6 529
NP_033906.2 Serping1 gene product M. musculus 80.2 503
Other hits (2 of 13) [Show all]SpeciesId(%)Len(aa)
XP_003909898.1 PREDICTED: plasma protease C1 inhibitor isoform 1 P. anubis 96.6 503
XP_001092271.2 PREDICTED: plasma protease C1 inhibitor M. mulatta 96.4 499

GENE EXPRESSION
Tissues and development stages from this gene's sequences survey gene expression. Links to other NCBI expression resources.
EST Profile: Approximate expression patterns inferred from EST sources.
[Show more entries with profiles like this]
GEO Profiles: Experimental gene expression data (Gene Expression Omnibus).
cDNA Sources: liver; brain; connective tissue; placenta; lung; uterus; eye; stomach; heart; intestine; mammary gland; mixed; testis; pancreas; prostate; kidney; bladder; ovary; uncharacterized tissue; skin; thymus; adrenal gland; spleen; blood; embryonic tissue; umbilical cord; mouth; pharynx; parathyroid; cervix; ganglia; adipose tissue; bone; trachea; muscle; esophagus; nerve; vascular; larynx; pituitary gland; thyroid; bone marrow; epididymis; lymph node; pineal gland
MAPPING POSITION
Genomic location specified by transcript mapping, radiation hybrid mapping, genetic mapping or cytogenetic mapping.
Chromosome: 11
Map position: 11q12.1
UniSTS entry: Chr 11 RH11451
UniSTS entry: Chr 11 D11S3986 [Map Viewer]
UniSTS entry: Chr 11 G62069
UniSTS entry: Chr 11 C1NH
UniSTS entry: Chr 22 RH80142
UniSTS entry: Chr 11 SHGC-6014
UniSTS entry: Chr 1 SHGC-30251 [Map Viewer]
SEQUENCES
Sequences representing this gene; mRNAs, ESTs, and gene predictions supported by transcribed sequences.

mRNA sequences (17)

BT006966.1 Homo sapiens serine (or cysteine) proteinase inhibitor, clade G (C1 inhibitor), member 1, (angioedema, hereditary) mRNA, complete cds P
NM_000062.2 Homo sapiens serpin peptidase inhibitor, clade G (C1 inhibitor), member 1 (SERPING1), transcript variant 1, mRNA PA
M13656.1 Human plasma protease (C1) inhibitor mRNA, complete cds P
AY732486.1 Homo sapiens serine/cysteine proteinase inhibitor clade G member 1 splice variant 3 (SERPING1) mRNA, complete cds, alternatively spliced P
AY732485.1 Homo sapiens serine/cysteine proteinase inhibitor clade G member 1 splice variant 2 (SERPING1) mRNA, partial cds, alternatively spliced P
AB209826.1 Homo sapiens mRNA for Plasma protease C1 inhibitor precursor variant protein P
NM_001032295.1 Homo sapiens serpin peptidase inhibitor, clade G (C1 inhibitor), member 1 (SERPING1), transcript variant 2, mRNA PA
BC011171.2 Homo sapiens serpin peptidase inhibitor, clade G (C1 inhibitor), member 1, mRNA (cDNA clone MGC:17091 IMAGE:4150091), complete cds PA
AK293054.1 Homo sapiens cDNA FLJ78023 complete cds, highly similar to Homo sapiens serine (or cysteine) proteinase inhibitor, clade G (C1inhibitor), member 1, (angioedema, hereditary) (SERPING1), mRNA PA
AK312626.1 Homo sapiens cDNA, FLJ93010, highly similar to Homo sapiens serine (or cysteine) proteinase inhibitor, clade G (C1inhibitor), member 1, (angioedema, hereditary) (SERPING1), mRNA P
AK303840.1 Homo sapiens cDNA FLJ58564 complete cds, highly similar to Plasma protease C1 inhibitor precursor PA
AK303809.1 Homo sapiens cDNA FLJ58826 complete cds, highly similar to Plasma protease C1 inhibitor precursor P
X07577.1 Human mRNA for C1 inhibitor P
M13203.1 Human first component of complement (C1) inhibitor mRNA P
M14036.1 Human C1 inhibitor mRNA, 3' end P
GU727623.1 Homo sapiens epididymis tissue protein Li 173 mRNA, complete cds PA
M13690.1 Human plasma protease (C1) inhibitor mRNA, complete cds P

EST sequences (10 of 1620) [Show all sequences]

AA961522.1 Clone IMAGE:1592533 kidney 3' read A
AA962490.1 Clone IMAGE:1573600 kidney 3' read A
AA970473.1 Clone IMAGE:1574767 kidney 3' read A
AA974791.1 Clone IMAGE:1558540 lung 3' read A
AA995852.1 Clone IMAGE:1611960 uncharacterized tissue 3' read A
AI018053.1 Clone IMAGE:1642093 testis 3' read A
AI018101.1 Clone IMAGE:1642178 testis 3' read A
AI024034.1 Clone IMAGE:1642824 testis 3' read A
AI038799.1 Clone IMAGE:1664139 skin 3' read A
AI038921.1 Clone IMAGE:1664216 skin 3' read PA


Key to Symbols

P Has similarity to known Proteins (after translation)
A Contains a poly-Adenylation signal
S Sequence is a Suboptimal member of this cluster
M Clone is putatively CDS-complete by MGC criteria

 
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