> BMI1 polycomb ring finger oncogene (BMI1)
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UGID:203719     UniGene Hs.380403     Homo sapiens (human)   BMI1
BMI1 polycomb ring finger oncogene (BMI1)

Human protein-coding gene BMI1. Represented by 275 ESTs from 176 cDNA libraries. Corresponds to 2 reference sequences (different isoforms). [UniGene 203719 - Hs.380403]

SELECTED PROTEIN SIMILARITIES
Comparison of cluster transcripts with RefSeq proteins. The alignments can suggest function of the cluster.
Best Hits and Hits from model organismsSpeciesId(%)Len(aa)
NP_001190991.1 COMMD3-BMI1 gene product H. sapiens 100.0 468
XP_001147119.2 PREDICTED: polycomb complex protein BMI-1 isoform 2, partial P. troglodytes 100.0 331
XP_003903504.1 PREDICTED: polycomb complex protein BMI-1 P. anubis 99.8 468
NP_001033161.1 BMI1 gene product B. taurus 99.7 325
NP_031578.2 Bmi1 gene product M. musculus 99.1 323
NP_001088007.1 polycomb complex protein BMI-1-B X. laevis 93.5 322
NP_919347.1 bmi1a gene product D. rerio 90.6 319
NP_523725.2 posterior sex combs D. melanogaster 45.7 210
Other hits (2 of 27) [Show all]SpeciesId(%)Len(aa)
XP_002805629.1 PREDICTED: polycomb complex protein BMI-1 isoform 2 M. mulatta 99.4 352
XP_858578.1 PREDICTED: polycomb complex protein BMI-1 isoform 3 C. lupus familiaris 99.4 325

GENE EXPRESSION
Tissues and development stages from this gene's sequences survey gene expression. Links to other NCBI expression resources.
EST Profile: Approximate expression patterns inferred from EST sources.
[Show more entries with profiles like this]
GEO Profiles: Experimental gene expression data (Gene Expression Omnibus).
cDNA Sources: brain; mixed; testis; vascular; blood; pituitary gland; lung; intestine; stomach; bone marrow; kidney; uncharacterized tissue; liver; mammary gland; placenta; eye; pancreas; connective tissue; prostate; adrenal gland; thyroid; bone; bladder; heart; pharynx; thymus; skin; ovary; uterus; embryonic tissue; muscle; mouth; parathyroid; esophagus; salivary gland; lymph node; spleen; trachea; ascites; pineal gland
MAPPING POSITION
Genomic location specified by transcript mapping, radiation hybrid mapping, genetic mapping or cytogenetic mapping.
Chromosome: 10
Map position: 10p11.23
UniSTS entry: Chr 10 D2S238E
UniSTS entry: Chr 10 WI-11394 [Map Viewer]
UniSTS entry: Chr 10 MARC_15438-15451:1010160821:5
UniSTS entry: Chr 10 D10S2352 [Map Viewer]
SEQUENCES
Sequences representing this gene; mRNAs, ESTs, and gene predictions supported by transcribed sequences.

mRNA sequences (7)

NM_005180.8 Homo sapiens BMI1 polycomb ring finger oncogene (BMI1), mRNA P
CR456911.1 Homo sapiens full open reading frame cDNA clone RZPDo834E1018D for gene COMMD3, COMM domain containing 3; complete cds, incl. stopcodon P
BT019450.1 Homo sapiens B lymphoma Mo-MLV insertion region (mouse) mRNA, complete cds P
BC011652.2 Homo sapiens BMI1 polycomb ring finger oncogene, mRNA (cDNA clone MGC:12685 IMAGE:4138748), complete cds PA
NM_001204062.1 Homo sapiens COMMD3-BMI1 readthrough (COMMD3-BMI1), mRNA P
AH004292.1 Homo sapiens flvi-2/bmi-1 (flvi-2/bmi-1) mRNA, partial cds P
L13689.1 Human prot-oncogene (BMI-1) mRNA, complete cds P

EST sequences (10 of 275) [Show all sequences]

AI039078.1 Clone IMAGE:1657489 embryonic tissue 3' read
AI078645.1 Clone IMAGE:1667889 parathyroid 3' read
AI093307.1 Clone IMAGE:1695049 uterus 3' read A
AI123472.1 Clone IMAGE:1640697 testis 3' read PA
AI168565.1 Clone IMAGE:1655986 mixed 3' read A
BX091302.1 Clone IMAGp998J101818_;_IMAGE:740457 ovary PA
AI186887.1 Clone IMAGE:1740282 lung 3' read P
AI221355.1 Clone IMAGE:1841579 mixed 3' read A
AI250869.1 Clone IMAGE:2000941 lymph node 3' read A
CB163576.1 Clone L17N670205n1-32-H12 liver 5' read


Key to Symbols

P Has similarity to known Proteins (after translation)
A Contains a poly-Adenylation signal
S Sequence is a Suboptimal member of this cluster
M Clone is putatively CDS-complete by MGC criteria

 
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