Platelet/endothelial cell adhesion molecule 1 (PECAM1)

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UGID:201592 UniGene Hs.376675 Homo sapiens (human) PECAM1

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Platelet/endothelial cell adhesion molecule 1 (PECAM1)

Human protein-coding gene PECAM1. Represented by 208 ESTs from 94 cDNA libraries. Corresponds to reference sequence NM_000442.4. [UniGene 201592 - Hs.376675]

SELECTED PROTEIN SIMILARITIES

Comparison of cluster transcripts with RefSeq proteins. The alignments can suggest function of the cluster.

Best Hits and Hits from model organisms		Species	Id(%)	Len(aa)
NP_000433.4 Conserved domains (CDD) Gene summary Protein sequence Protein/EST matches (ProtEST) Protein/protein matches (BLink)	PECAM1 gene product	H. sapiens	100.0	737
NP_032842.2 Conserved domains (CDD) Gene summary Protein sequence Protein/EST matches (ProtEST) Protein/protein matches (BLink)	Pecam1 gene product	M. musculus	66.5	710
Other hits (2 of 12) [Show all]		Species	Id(%)	Len(aa)
XP_511582.2 Conserved domains (CDD) Gene summary Protein sequence Protein/EST matches (ProtEST) Protein/protein matches (BLink)	PREDICTED: platelet endothelial cell adhesion molecule isoform 9	P. troglodytes	99.5	737
XP_003913343.1 Conserved domains (CDD) Gene summary Protein sequence Protein/EST matches (ProtEST) Protein/protein matches (BLink)	PREDICTED: platelet endothelial cell adhesion molecule	P. anubis	91.7	737

GENE EXPRESSION

Tissues and development stages from this gene's sequences survey gene expression. Links to other NCBI expression resources.

	EST Profile:	Approximate expression patterns inferred from EST sources. [Show more entries with profiles like this]
	GEO Profiles:	Experimental gene expression data (Gene Expression Omnibus).
	cDNA Sources:	placenta; lung; pancreas; vascular; blood; eye; kidney; adipose tissue; tonsil; epididymis; connective tissue; mixed; thymus; prostate; uncharacterized tissue; embryonic tissue; brain; intestine; stomach; heart; uterus; testis; skin; larynx; thyroid; ganglia; umbilical cord; nerve; mammary gland; lymph node; parathyroid; muscle

MAPPING POSITION

Genomic location specified by transcript mapping, radiation hybrid mapping, genetic mapping or cytogenetic mapping.

Chromosome:	17
Map position:	17q23.3
UniSTS entry:	Chr 17	RH11535	[Map Viewer]
UniSTS entry:	Chr 17	RH17926	[Map Viewer]
UniSTS entry:	Chr 17	G60155
UniSTS entry:	Chr 17	D17S1992	[Map Viewer]
UniSTS entry:	Chr 17	RH11719	[Map Viewer]
UniSTS entry:		G44352
UniSTS entry:	Chr 1	D10S16
UniSTS entry:	Chr 11	COX8
UniSTS entry:	Chr 17	PECAM1_v371
UniSTS entry:	Chr 1	D11S2921

SEQUENCES

Sequences representing this gene; mRNAs, ESTs, and gene predictions supported by transcribed sequences.

mRNA sequences (9)

M37780.1	Human leukocyte surface protein (CD31) mRNA, complete cds	P
M28526.1	Human platelet endothelial cell adhesion molecule (PECAM-1) mRNA, complete cds	P
BC051822.1	Homo sapiens platelet/endothelial cell adhesion molecule, mRNA (cDNA clone MGC:60076 IMAGE:5768579), complete cds	PA
NM_000442.4	Homo sapiens platelet/endothelial cell adhesion molecule 1 (PECAM1), mRNA	PA
BC022512.1	Homo sapiens platelet/endothelial cell adhesion molecule, mRNA (cDNA clone MGC:26550 IMAGE:4816878), complete cds	PA
AK290692.1	Homo sapiens cDNA FLJ76270 complete cds, highly similar to Homo sapiens platelet/endothelial cell adhesion molecule (CD31 antigen) (PECAM1), mRNA	P
AK091419.1	Homo sapiens cDNA FLJ34100 fis, clone FCBBF3007597	A
AK304166.1	Homo sapiens cDNA FLJ58394 complete cds, highly similar to Platelet endothelial cell adhesion molecule precursor	P
AK303959.1	Homo sapiens cDNA FLJ57480 complete cds, moderately similar to Platelet endothelial cell adhesion molecule precursor	P

EST sequences (10 of 208) [Show all sequences]

AA989482.1	Clone IMAGE:1606254	kidney	3' read	A
AI001823.1	Clone IMAGE:1638110	testis	3' read	A
AI081733.1	Clone IMAGE:1632438	mammary gland	3' read	A
AI092661.1	Clone IMAGE:1693058	heart	3' read	A
AI094058.1	Clone IMAGE:1688324	mixed	3' read	A
R22412.1	Clone IMAGE:130541	placenta	3' read	A
AI127297.1	Clone IMAGE:1705857	heart	3' read
CB047629.1	Clone IMAGE:3253167	kidney	3' read	A
CB047630.1	Clone IMAGE:3253167	kidney	5' read
AI148740.1	Clone IMAGE:1714473	placenta	3' read	A

Key to Symbols

P Has similarity to known Proteins (after translation)
A Contains a poly-Adenylation signal
S Sequence is a Suboptimal member of this cluster
M Clone is putatively CDS-complete by MGC criteria