> Ewing sarcoma breakpoint region 1 (EWSR1)
NCBI UniGene banner graphic
PubMed Nucleotide Protein Genome Structure Popset Taxonomy
 Search
NCBI

UniGene
Homepage
FAQs
Help
Query Tips
Build Info
Library Browser
DDD
Download UniGene

Related Databases
Gene
HomoloGene
EST
SRA

NIH cDNA Projects
MGC | ZGC | XGC
Finding cDNAs
UGID:200690     UniGene Hs.374477     Homo sapiens (human)   EWSR1 Order cDNA clone, Links
Ewing sarcoma breakpoint region 1 (EWSR1)

Human protein-coding gene EWSR1. Represented by 2116 ESTs from 490 cDNA libraries. Corresponds to 5 reference sequences (different isoforms). [UniGene 200690 - Hs.374477]

SELECTED PROTEIN SIMILARITIES
Comparison of cluster transcripts with RefSeq proteins. The alignments can suggest function of the cluster.
Best Hits and Hits from model organismsSpeciesId(%)Len(aa)
XP_001104497.1 PREDICTED: RNA-binding protein EWS-like isoform 4 M. mulatta 100.0 660
NP_053733.2 EWSR1 gene product H. sapiens 100.0 660
XP_003905432.1 PREDICTED: RNA-binding protein EWS P. anubis 100.0 654
XP_001173113.2 PREDICTED: RNA-binding protein EWS isoform 4 P. troglodytes 100.0 654
XP_003365516.1 PREDICTED: RNA-binding protein EWS-like E. caballus 100.0 354
XP_003433443.1 PREDICTED: RNA-binding protein EWS C. lupus familiaris 99.8 660
NP_001238977.1 RNA-binding protein EWS S. scrofa 99.8 655
NP_001103270.1 EWSR1 gene product B. taurus 99.7 654
XP_004017689.1 PREDICTED: RNA-binding protein EWS O. aries 99.5 656
NP_031994.2 Ewsr1 gene product M. musculus 99.4 654
NP_001089902.1 uncharacterized protein LOC734969 X. laevis 78.6 666
NP_001108610.1 ewsr1a gene product D. rerio 68.3 623
NP_523365.2 cabeza, isoform B D. melanogaster 49.5 295
Other hits (2 of 22) [Show all]SpeciesId(%)Len(aa)
XP_003749732.1 PREDICTED: RNA-binding protein EWS-like isoform 2 R. norvegicus 99.4 660
XP_002715944.1 PREDICTED: Ewing sarcoma breakpoint region 1-like isoform 1 O. cuniculus 98.8 649

GENE EXPRESSION
Tissues and development stages from this gene's sequences survey gene expression. Links to other NCBI expression resources.
EST Profile: Approximate expression patterns inferred from EST sources.
[Show more entries with profiles like this]
GEO Profiles: Experimental gene expression data (Gene Expression Omnibus).
cDNA Sources: brain; uncharacterized tissue; testis; placenta; embryonic tissue; uterus; eye; skin; kidney; intestine; blood; liver; lung; muscle; thymus; mixed; prostate; lymph; connective tissue; pancreas; vascular; spleen; mammary gland; tonsil; ear; stomach; heart; lymph node; ovary; bone marrow; bladder; pharynx; trachea; adrenal gland; cervix; bone; thyroid; ascites; mouth; larynx; salivary gland; nerve; ganglia; pituitary gland; umbilical cord; esophagus; adipose tissue
MAPPING POSITION
Genomic location specified by transcript mapping, radiation hybrid mapping, genetic mapping or cytogenetic mapping.
Chromosome: 22
Map position: 22q12.2
UniSTS entry: GDB:452619
UniSTS entry: Ewsh
UniSTS entry: Chr 22 G06555
UniSTS entry: Ewsr1
UniSTS entry: Chr 22 SGC38366 [Map Viewer]
UniSTS entry: Chr 22 SHGC-37092 [Map Viewer]
UniSTS entry: Chr 22 STS-N54946 [Map Viewer]
UniSTS entry: Ewsr1
UniSTS entry: STS-N54946
SEQUENCES
Sequences representing this gene; mRNAs, ESTs, and gene predictions supported by transcribed sequences.

mRNA sequences (23)

BX648769.1 Homo sapiens mRNA; cDNA DKFZp686M2044 (from clone DKFZp686M2044) PA
AK127624.1 Homo sapiens cDNA FLJ45722 fis, clone HCASM2008154, weakly similar to RNA-binding protein EWS P
NM_005243.3 Homo sapiens Ewing sarcoma breakpoint region 1 (EWSR1), transcript variant 2, mRNA PA
CR456490.1 Homo sapiens EWSR1 full length open reading frame (ORF) cDNA clone (cDNA clone C22ORF:pGEM.EWSR1) P
BC072442.1 Homo sapiens Ewing sarcoma breakpoint region 1, mRNA (cDNA clone MGC:87992 IMAGE:6047805), complete cds PA
NM_013986.3 Homo sapiens Ewing sarcoma breakpoint region 1 (EWSR1), transcript variant 1, mRNA PA
AK026270.1 Homo sapiens cDNA: FLJ22617 fis, clone HSI05379, highly similar to HSEWS Homo sapiens EWS mRNA PA
BC000527.2 Homo sapiens Ewing sarcoma breakpoint region 1, mRNA (cDNA clone MGC:8607 IMAGE:2961279), complete cds PA
AK225102.1 Homo sapiens mRNA for Ewing sarcoma breakpoint region 1 isoform EWS variant, clone: CAS09229 PA
AK225096.1 Homo sapiens mRNA for Ewing sarcoma breakpoint region 1 isoform EWS variant, clone: CAS06131 PA
BC004817.1 Homo sapiens Ewing sarcoma breakpoint region 1, mRNA (cDNA clone MGC:5432 IMAGE:3449145), complete cds PA
BC011048.1 Homo sapiens Ewing sarcoma breakpoint region 1, mRNA (cDNA clone MGC:16900 IMAGE:4340116), complete cds PA
AK056681.1 Homo sapiens cDNA FLJ32119 fis, clone PEBLM1000034, highly similar to RNA-BINDING PROTEIN EWS P
AK056309.1 Homo sapiens cDNA FLJ31747 fis, clone NT2RI2007377, highly similar to RNA-BINDING PROTEIN EWS PA
EU327511.1 Homo sapiens EWSR1/ZNF384 fusion protein (EWSR1/ZNF384 fusion) mRNA, partial cds P
AK096787.1 Homo sapiens cDNA FLJ39468 fis, clone PROST2012504, highly similar to RNA-BINDING PROTEIN EWS PA
AL833489.1 Homo sapiens mRNA; cDNA DKFZp686I2029 (from clone DKFZp686I2029) PA
FJ573261.1 Homo sapiens isolate M01 EWSR1/NFATC2 fusion protein mRNA, partial cds P
NM_001163287.1 Homo sapiens Ewing sarcoma breakpoint region 1 (EWSR1), transcript variant 5, mRNA PA
NM_001163286.1 Homo sapiens Ewing sarcoma breakpoint region 1 (EWSR1), transcript variant 4, mRNA PA
NM_001163285.1 Homo sapiens Ewing sarcoma breakpoint region 1 (EWSR1), transcript variant 3, mRNA PA
X66899.1 H.sapiens EWS mRNA PA
JN624779.1 Homo sapiens EWSR1/ATF1 fusion protein type 7 mRNA, partial cds

EST sequences (10 of 2116) [Show all sequences]

AA968521.1 Clone IMAGE:1575011 kidney 3' read A
AA970893.1 Clone IMAGE:1572666 kidney 3' read A
AA975296.1 Clone IMAGE:1588482 uncharacterized tissue 3' read A
AA988441.1 Clone IMAGE:1601891 lung 3' read
AA993087.1 Clone IMAGE:1625044 embryonic tissue 3' read A
AA911782.1 Clone IMAGE:1519664 uncharacterized tissue 3' read A
AI016994.1 Clone IMAGE:1635250 kidney 3' read PA
AA922583.1 Clone IMAGE:1551661 uncharacterized tissue 3' read A
AI091290.1 Clone IMAGE:1651412 mixed 3' read
CA976085.1 Clone IMAGE:6202495 nerve 5' read A


Key to Symbols

P Has similarity to known Proteins (after translation)
A Contains a poly-Adenylation signal
S Sequence is a Suboptimal member of this cluster
M Clone is putatively CDS-complete by MGC criteria

 
NLM | NIH | UniGene | Privacy Statement | Disclaimer | NCBI Help