Rho GTPase activating protein 23 (ARHGAP23)

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UGID:200680 UniGene Hs.374446 Homo sapiens (human) ARHGAP23

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Rho GTPase activating protein 23 (ARHGAP23)

Human protein-coding gene ARHGAP23. Represented by 243 ESTs from 113 cDNA libraries. Corresponds to reference sequence NM_001199417.1. [UniGene 200680 - Hs.374446]

SELECTED PROTEIN SIMILARITIES

Comparison of cluster transcripts with RefSeq proteins. The alignments can suggest function of the cluster.

Best Hits and Hits from model organisms		Species	Id(%)	Len(aa)
NP_001186346.1 Conserved domains (CDD) Gene summary Protein sequence Protein/EST matches (ProtEST) Protein/protein matches (BLink)	ARHGAP23 gene product	H. sapiens	100.0	1490
NP_067468.2 Conserved domains (CDD) Gene summary Protein sequence Protein/EST matches (ProtEST) Protein/protein matches (BLink)	rho GTPase-activating protein 23	M. musculus	94.6	1276
XP_690730.5 Conserved domains (CDD) Gene summary Protein sequence Protein/EST matches (ProtEST) Protein/protein matches (BLink)	PREDICTED: rho GTPase-activating protein 23	D. rerio	66.5	1047
NP_001083524.1 Conserved domains (CDD) Gene summary Protein sequence Protein/EST matches (ProtEST) Protein/protein matches (BLink)	rho GTPase-activating protein 21-B	X. laevis	61.9	1391
NP_001129833.1 Conserved domains (CDD) Gene summary Protein sequence Protein/EST matches (ProtEST) Protein/protein matches (BLink)	Protein PAC-1, isoform b	C. elegans	52.6	228
Other hits (2 of 31) [Show all]		Species	Id(%)	Len(aa)
XP_003912950.1 Conserved domains (CDD) Gene summary Protein sequence Protein/EST matches (ProtEST) Protein/protein matches (BLink)	PREDICTED: rho GTPase-activating protein 23	P. anubis	99.1	1490
XP_001082710.2 Conserved domains (CDD) Gene summary Protein sequence Protein/EST matches (ProtEST) Protein/protein matches (BLink)	PREDICTED: rho GTPase-activating protein 23-like	M. mulatta	98.2	1505

GENE EXPRESSION

Tissues and development stages from this gene's sequences survey gene expression. Links to other NCBI expression resources.

	EST Profile:	Approximate expression patterns inferred from EST sources. [Show more entries with profiles like this]
	GEO Profiles:	Experimental gene expression data (Gene Expression Omnibus).
	cDNA Sources:	brain; mouth; mixed; lung; uncharacterized tissue; embryonic tissue; kidney; placenta; thyroid; amniotic fluid; ovary; cervix; mammary gland; lymph node; pharynx; bone; stomach; adrenal gland; prostate; intestine; larynx; connective tissue; salivary gland; eye; heart; thymus; bladder; uterus; testis; ear; spleen; nerve; pancreas; liver; ganglia

MAPPING POSITION

Genomic location specified by transcript mapping, radiation hybrid mapping, genetic mapping or cytogenetic mapping.

Chromosome:	17
Map position:	17q12
UniSTS entry:	Chr 17	A004B30	[Map Viewer]
UniSTS entry:	Chr 17	RH91175
UniSTS entry:	Chr 17	D17S1381E

SEQUENCES

Sequences representing this gene; mRNAs, ESTs, and gene predictions supported by transcribed sequences.

mRNA sequences (2)

	NM_001199417.1	Homo sapiens Rho GTPase activating protein 23 (ARHGAP23), mRNA	PA
	BC039190.1	Homo sapiens Rho GTPase activating protein 23, mRNA (cDNA clone IMAGE:4155911)	P

EST sequences (10 of 243) [Show all sequences]

AA984381.1	Clone IMAGE:1629890	brain	3' read	P
R21484.1	Clone IMAGE:31371	brain	5' read
AI123323.1	Clone IMAGE:1689961	mixed	3' read	P
AI127086.1	Clone IMAGE:1708086	heart	3' read	P
AI131432.1	Clone IMAGE:1710020	heart	3' read	P
AI160612.1	Clone IMAGE:1716319	placenta	3' read	P
AI205039.1	Clone IMAGE:1684589	brain	3' read	P
AI220530.1	Clone IMAGE:1838495	testis	3' read	A
AI262729.1	Clone IMAGE:1725382	placenta	3' read	A
AI243766.1	Clone IMAGE:1854154	mixed	3' read	A

Key to Symbols

P Has similarity to known Proteins (after translation)
A Contains a poly-Adenylation signal
S Sequence is a Suboptimal member of this cluster
M Clone is putatively CDS-complete by MGC criteria