> Ubiquitin protein ligase E3B (UBE3B)
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UGID:200516     UniGene Hs.374067     Homo sapiens (human)   UBE3B
Ubiquitin protein ligase E3B (UBE3B)

Human protein-coding gene UBE3B. Represented by 477 ESTs from 215 cDNA libraries. Corresponds to 5 reference sequences (different isoforms). [UniGene 200516 - Hs.374067]

SELECTED PROTEIN SIMILARITIES
Comparison of cluster transcripts with RefSeq proteins. The alignments can suggest function of the cluster.
Best Hits and Hits from model organismsSpeciesId(%)Len(aa)
XP_001137003.2 PREDICTED: ubiquitin-protein ligase E3B isoform 3 P. troglodytes 100.0 1067
NP_904324.1 UBE3B gene product H. sapiens 100.0 1067
XP_003907175.1 PREDICTED: ubiquitin-protein ligase E3B isoform 1 P. anubis 99.5 1067
NP_473434.2 Ube3b gene product M. musculus 95.9 1069
NP_001108154.1 ubiquitin-protein ligase E3B D. rerio 88.3 1068
NP_499392.1 Protein OXI-1 C. elegans 63.6 537
NP_648279.1 CG5087, isoform A D. melanogaster 59.4 1075
NP_001118648.1 E3 ubiquitin-protein ligase UPL6 A. thaliana 48.9 352
XP_001695431.1 predicted protein C. reinhardtii 47.3 187
NP_001080799.1 ubiquitin protein ligase E3C X. laevis 47.2 288
Other hits (2 of 49) [Show all]SpeciesId(%)Len(aa)
XP_002798818.1 PREDICTED: ubiquitin-protein ligase E3B-like M. mulatta 99.2 1032
XP_001500690.1 PREDICTED: ubiquitin-protein ligase E3B E. caballus 98.3 1067

GENE EXPRESSION
Tissues and development stages from this gene's sequences survey gene expression. Links to other NCBI expression resources.
EST Profile: Approximate expression patterns inferred from EST sources.
[Show more entries with profiles like this]
GEO Profiles: Experimental gene expression data (Gene Expression Omnibus).
cDNA Sources: mixed; brain; kidney; uncharacterized tissue; ovary; placenta; bladder; muscle; trachea; skin; spleen; uterus; bone; stomach; vascular; salivary gland; adrenal gland; eye; testis; lymph node; lung; ear; pharynx; intestine; prostate; pancreas; cervix; embryonic tissue; amniotic fluid; blood; liver; heart; bone marrow; mammary gland; thyroid; lymph; parathyroid; mouth; thymus; larynx; pituitary gland; connective tissue; adipose tissue; ganglia; ascites
MAPPING POSITION
Genomic location specified by transcript mapping, radiation hybrid mapping, genetic mapping or cytogenetic mapping.
Chromosome: 12
Map position: 12q24.11
UniSTS entry: Chr 12 RH46180 [Map Viewer]
UniSTS entry: Chr 12 RH80161
UniSTS entry: Chr 12 WI-20952 [Map Viewer]
UniSTS entry: Chr 12 MARC_12083-12084:1008774253:1
UniSTS entry: Chr 12 WI-11698 [Map Viewer]
UniSTS entry: Chr 12 RH70162
SEQUENCES
Sequences representing this gene; mRNAs, ESTs, and gene predictions supported by transcribed sequences.

mRNA sequences (22)

BC051266.1 Homo sapiens ubiquitin protein ligase E3B, mRNA (cDNA clone IMAGE:4640971), complete cds PA
BX537403.1 Homo sapiens mRNA; cDNA DKFZp686A1051 (from clone DKFZp686A1051); complete cds PA
NM_183415.2 Homo sapiens ubiquitin protein ligase E3B (UBE3B), transcript variant 3, mRNA P
BC068221.1 Homo sapiens ubiquitin protein ligase E3B, mRNA (cDNA clone IMAGE:6573521), complete cds PA
BC108705.1 Homo sapiens ubiquitin protein ligase E3B, mRNA (cDNA clone IMAGE:6022049), complete cds PA
AF251046.2 Homo sapiens UBE3B variant 1 (UBE3B) mRNA, complete cds PA
BC141880.1 Homo sapiens ubiquitin protein ligase E3B, mRNA (cDNA clone MGC:150672 IMAGE:40124513), complete cds P
BC013182.1 Homo sapiens ubiquitin protein ligase E3B, mRNA (cDNA clone IMAGE:4345655), with apparent retained intron A
AK056015.1 Homo sapiens cDNA FLJ31453 fis, clone NT2NE2001048
AK307385.1 Homo sapiens cDNA, FLJ97333 P
AK304678.1 Homo sapiens cDNA FLJ51548 complete cds, highly similar to Homo sapiens ubiquitin protein ligase E3B (UBE3B), transcript variant 3, mRNA P
BC032301.1 Homo sapiens ubiquitin protein ligase E3B, mRNA (cDNA clone IMAGE:5167597), partial cds P
BC020348.1 Homo sapiens ubiquitin protein ligase E3B, mRNA (cDNA clone IMAGE:3464523) P
AF130072.1 Homo sapiens clone FLB9127 mRNA sequence P
BC144684.1 Homo sapiens cDNA clone IMAGE:9053218 P
AK301036.1 Homo sapiens cDNA FLJ51547 complete cds, moderately similar to Homo sapiens ubiquitin protein ligase E3B (UBE3B), transcript variant 3, mRNA P
BC150637.1 Homo sapiens ubiquitin protein ligase E3B, mRNA (cDNA clone MGC:183547 IMAGE:9057007), complete cds P
NM_001270451.1 Homo sapiens ubiquitin protein ligase E3B (UBE3B), transcript variant 6, mRNA PA
NM_001270449.1 Homo sapiens ubiquitin protein ligase E3B (UBE3B), transcript variant 4, mRNA PA
NM_001270450.1 Homo sapiens ubiquitin protein ligase E3B (UBE3B), transcript variant 5, mRNA PA
BC040155.1 Homo sapiens ubiquitin protein ligase E3B, mRNA (cDNA clone IMAGE:4386468), with apparent retained intron PA
NM_130466.3 Homo sapiens ubiquitin protein ligase E3B (UBE3B), transcript variant 1, mRNA P

EST sequences (10 of 477) [Show all sequences]

AA865731.1 Clone IMAGE:1469238 uncharacterized tissue 3' read P
AA970103.1 Clone IMAGE:1581735 mixed 3' read
AA975049.1 Clone IMAGE:1555567 kidney 3' read
AA992467.1 Clone IMAGE:1602787 lung 3' read P
AA993988.1 Clone IMAGE:1628904 mixed 3' read P
AI004181.1 Clone IMAGE:1631811 mammary gland 3' read P
AI017028.1 Clone IMAGE:1635283 kidney 3' read
AI027749.1 Clone IMAGE:1644928 testis 3' read A
AI032464.1 Clone IMAGE:1652444 mixed 3' read
AI034041.1 Clone IMAGE:1646832 parathyroid 3' read


Key to Symbols

P Has similarity to known Proteins (after translation)
A Contains a poly-Adenylation signal
S Sequence is a Suboptimal member of this cluster
M Clone is putatively CDS-complete by MGC criteria

 
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