> Kruppel-like factor 12 (KLF12)
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UGID:200392     UniGene Hs.373857     Homo sapiens (human)   KLF12
Kruppel-like factor 12 (KLF12)

Human protein-coding gene KLF12. Represented by 207 ESTs from 110 cDNA libraries. Corresponds to reference sequence NM_007249.4. [UniGene 200392 - Hs.373857]

SELECTED PROTEIN SIMILARITIES
Comparison of cluster transcripts with RefSeq proteins. The alignments can suggest function of the cluster.
Best Hits and Hits from model organismsSpeciesId(%)Len(aa)
NP_001245058.1 Krueppel-like factor 12 M. mulatta 100.0 401
XP_003314223.1 PREDICTED: LOW QUALITY PROTEIN: Krueppel-like factor 12 P. troglodytes 100.0 401
NP_009180.3 KLF12 gene product H. sapiens 100.0 401
XP_003913997.1 PREDICTED: Krueppel-like factor 12 P. anubis 100.0 249
NP_034766.2 Klf12 gene product M. musculus 97.3 401
NP_611747.2 CG42741 D. melanogaster 80.9 88
NP_001103335.1 klf12b gene product D. rerio 71.5 340
NP_001082615.1 Kruppel-like factor 8 X. laevis 50.3 329
NP_001022204.1 Protein KLF-3, isoform a C. elegans 48.0 151
Other hits (2 of 36) [Show all]SpeciesId(%)Len(aa)
XP_542612.3 PREDICTED: Kruppel-like factor 12 isoform 1 C. lupus familiaris 99.0 401
NP_001178199.2 Krueppel-like factor 12 B. taurus 99.0 401

GENE EXPRESSION
Tissues and development stages from this gene's sequences survey gene expression. Links to other NCBI expression resources.
EST Profile: Approximate expression patterns inferred from EST sources.
[Show more entries with profiles like this]
GEO Profiles: Experimental gene expression data (Gene Expression Omnibus).
cDNA Sources: brain; uterus; intestine; liver; testis; blood; skin; mammary gland; connective tissue; vascular; trachea; spleen; thymus; eye; lymph node; lung; bone; mixed; uncharacterized tissue; embryonic tissue; kidney; pharynx; stomach; pancreas; heart; bone marrow; pituitary gland; muscle; adipose tissue; prostate; ovary
MAPPING POSITION
Genomic location specified by transcript mapping, radiation hybrid mapping, genetic mapping or cytogenetic mapping.
Chromosome: 13
Map position: 13q22
UniSTS entry: Chr 13 RH15688
UniSTS entry: Chr 13 WI-13803 [Map Viewer]
UniSTS entry: Chr 13 KLF12
UniSTS entry: Chr 13 RH103306
UniSTS entry: Chr 13 D13S681E
UniSTS entry: Chr 13 RH45383
UniSTS entry: Chr 13 G60008
UniSTS entry: Chr 13 KLF12_1562
SEQUENCES
Sequences representing this gene; mRNAs, ESTs, and gene predictions supported by transcribed sequences.

mRNA sequences (12)

AJ243274.1 Homo sapiens mRNA for AP-2rep protein (ap-2rep gene) P
AK126412.1 Homo sapiens cDNA FLJ44448 fis, clone UTERU2021917
NM_007249.4 Homo sapiens Kruppel-like factor 12 (KLF12), mRNA PA
AY584194.1 Homo sapiens clone C4 isolate JA Trypanosoma cruzi infected macrophage transcript J mRNA, partial sequence A
AF113122.1 Homo sapiens AP-2rep transcription factor mRNA, complete cds PA
AF330041.1 Homo sapiens AP-2 repressor mRNA, complete cds P
BC019680.1 Homo sapiens Kruppel-like factor 12, mRNA (cDNA clone MGC:24862 IMAGE:4942405), complete cds PA
AK291397.1 Homo sapiens cDNA FLJ75938 complete cds, highly similar to Homo sapiens Kruppel-like factor 12 (KLF12), transcript variant 1, mRNA P
AK096503.1 Homo sapiens cDNA FLJ39184 fis, clone OCBBF2004385
AK094419.1 Homo sapiens cDNA FLJ37100 fis, clone BRACE2019147
AF161471.1 Homo sapiens HSPC122 mRNA, complete cds PA
HF546212.1 Homo sapiens mRNA for Kruppel-like factor 12, splice variant 1 (KLF12 gene)

EST sequences (10 of 207) [Show all sequences]

R14539.1 Clone IMAGE:29213 brain 5' read
AA904480.1 Clone IMAGE:1507206 mixed 3' read
AI039315.1 Clone IMAGE:1658389 embryonic tissue 3' read A
AI090652.1 Clone IMAGE:1691628 heart 3' read
R23424.1 Clone IMAGE:34363 brain 5' read P
R23427.1 Clone IMAGE:34366 brain 5' read P
R23428.1 Clone IMAGE:34367 brain 5' read P
BX114927.1 Clone IMAGp998J174997_;_IMAGE:2030704 kidney
AI215580.1 Clone IMAGE:1844489 mixed 3' read
AI270906.1 Clone IMAGE:1996169 ovary 3' read


Key to Symbols

P Has similarity to known Proteins (after translation)
A Contains a poly-Adenylation signal
S Sequence is a Suboptimal member of this cluster
M Clone is putatively CDS-complete by MGC criteria

 
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