> N-myc downstream regulated 1 (NDRG1)
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UGID:200116     UniGene Hs.372914     Homo sapiens (human)   NDRG1
N-myc downstream regulated 1 (NDRG1)

Human protein-coding gene NDRG1. Represented by 3790 ESTs from 471 cDNA libraries. Corresponds to 4 reference sequences (different isoforms). [UniGene 200116 - Hs.372914]

SELECTED PROTEIN SIMILARITIES
Comparison of cluster transcripts with RefSeq proteins. The alignments can suggest function of the cluster.
Best Hits and Hits from model organismsSpeciesId(%)Len(aa)
XP_001088529.1 PREDICTED: protein NDRG1 isoform 5 M. mulatta 100.0 393
XP_003903232.1 PREDICTED: protein NDRG1 isoform 1 P. anubis 100.0 393
XP_001140617.1 PREDICTED: protein NDRG1 isoform 1 P. troglodytes 100.0 393
NP_001128714.1 NDRG1 gene product H. sapiens 100.0 393
NP_032707.2 Ndrg1 gene product M. musculus 96.7 393
NP_001080627.1 protein NDRG1-B X. laevis 85.6 395
NP_998513.2 ndrg1a gene product D. rerio 78.6 391
Other hits (2 of 21) [Show all]SpeciesId(%)Len(aa)
NP_001030181.1 NDRG1 gene product B. taurus 98.4 383
XP_004011982.1 PREDICTED: protein NDRG1 O. aries 98.4 378

GENE EXPRESSION
Tissues and development stages from this gene's sequences survey gene expression. Links to other NCBI expression resources.
EST Profile: Approximate expression patterns inferred from EST sources.
[Show more entries with profiles like this]
GEO Profiles: Experimental gene expression data (Gene Expression Omnibus).
cDNA Sources: brain; mouth; prostate; thymus; kidney; lung; connective tissue; testis; placenta; uterus; intestine; skin; uncharacterized tissue; vascular; eye; mammary gland; umbilical cord; trachea; stomach; spleen; liver; blood; pancreas; ovary; embryonic tissue; heart; bone; mixed; adrenal gland; esophagus; bladder; cervix; larynx; pharynx; parathyroid; bone marrow; lymph node; ganglia; thyroid; nerve; ascites; adipose tissue; ear; muscle; epididymis; pituitary gland
MAPPING POSITION
Genomic location specified by transcript mapping, radiation hybrid mapping, genetic mapping or cytogenetic mapping.
Chromosome: 8
Map position: 8q24.3
UniSTS entry: Chr 8 RH12615 [Map Viewer]
UniSTS entry: Chr 8 D8S1397E [Map Viewer]
UniSTS entry: Chr 8 RH12558 [Map Viewer]
SEQUENCES
Sequences representing this gene; mRNAs, ESTs, and gene predictions supported by transcribed sequences.

mRNA sequences (25)

AF004162.1 Homo sapiens nickel-specific induction protein (Cap43) mRNA, complete cds PA
AK129867.1 Homo sapiens cDNA FLJ26357 fis, clone HRT05043, highly similar to NDRG1 PROTEIN P
AK126924.1 Homo sapiens cDNA FLJ44977 fis, clone BRAWH3002513, highly similar to Protein NDRG1 P
NM_006096.3 Homo sapiens N-myc downstream regulated 1 (NDRG1), transcript variant 2, mRNA PA
CR456842.1 Homo sapiens full open reading frame cDNA clone RZPDo834C1011D for gene NDRG1, N-myc downstream regulated gene 1; complete cds, incl. stopcodon P
AY277597.1 Homo sapiens transformation-related protein 14 (TRG14) mRNA, complete cds P
AK223542.1 Homo sapiens mRNA for N-myc downstream regulated gene 1 variant, clone: FCC125F02 P
BC003175.1 Homo sapiens N-myc downstream regulated 1, mRNA (cDNA clone MGC:4412 IMAGE:2957847), complete cds PA
AK308117.1 Homo sapiens cDNA, FLJ98065 P
AK307829.1 Homo sapiens cDNA, FLJ97777 P
AK096562.1 Homo sapiens cDNA FLJ39243 fis, clone OCBBF2008283, highly similar to Protein NDRG1 P
AK095649.1 Homo sapiens cDNA FLJ38330 fis, clone FCBBF3025280, highly similar to NDRG1 PROTEIN P
AK091147.1 Homo sapiens cDNA FLJ33828 fis, clone CTONG2003599, highly similar to Protein NDRG1 P
NM_001135242.1 Homo sapiens N-myc downstream regulated 1 (NDRG1), transcript variant 1, mRNA PA
D87953.1 Homo sapiens mRNA for RTP, complete cds PA
AF230380.1 Homo sapiens N-myc downsteam regulated gene 1 (NDRG1) mRNA, partial cds
AF147402.1 Homo sapiens full length insert cDNA clone YN54B03 P
AF039944.1 Homo sapiens TARG1 mRNA, 3' untranslated region A
AK299636.1 Homo sapiens cDNA FLJ53648 complete cds, highly similar to Protein NDRG1 P
AK298236.1 Homo sapiens cDNA FLJ53637 complete cds, highly similar to Protein NDRG1 P
AK297342.1 Homo sapiens cDNA FLJ59927 complete cds, moderately similar to Protein NDRG1 P
AK296794.1 Homo sapiens cDNA FLJ55222 complete cds, highly similar to Protein NDRG1 P
NM_001258432.1 Homo sapiens N-myc downstream regulated 1 (NDRG1), transcript variant 3, mRNA PA
NM_001258433.1 Homo sapiens N-myc downstream regulated 1 (NDRG1), transcript variant 4, mRNA PA
X92845.1 H.sapiens mRNA for Drg1 protein PA

EST sequences (10 of 3790) [Show all sequences]

AA960823.1 Clone IMAGE:1552228 uncharacterized tissue 3' read A
AA962817.1 Clone IMAGE:1573730 kidney 3' read A
AA968975.1 Clone IMAGE:1574650 kidney 3' read A
AA970848.1 Clone IMAGE:1572624 kidney 3' read A
AA975372.1 Clone IMAGE:1588720 kidney 3' read A
AA978355.1 Clone IMAGE:1588793 kidney 3' read A
AA987786.1 Clone IMAGE:1588844 kidney 3' read A
AA887511.1 Clone IMAGE:1500524 lung 3' read A
AI050733.1 Clone IMAGE:1663955 skin 3' read A
AI075894.1 Clone IMAGE:1640390 testis 3' read A


Key to Symbols

P Has similarity to known Proteins (after translation)
A Contains a poly-Adenylation signal
S Sequence is a Suboptimal member of this cluster
M Clone is putatively CDS-complete by MGC criteria

 
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