> Cullin 3 (CUL3)
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UGID:199783     UniGene Hs.372286     Homo sapiens (human)   CUL3 Order cDNA clone, Links
Cullin 3 (CUL3)

Human protein-coding gene CUL3. Represented by 500 ESTs from 265 cDNA libraries. Corresponds to 3 reference sequences (different isoforms). [UniGene 199783 - Hs.372286]

SELECTED PROTEIN SIMILARITIES
Comparison of cluster transcripts with RefSeq proteins. The alignments can suggest function of the cluster.
Best Hits and Hits from model organismsSpeciesId(%)Len(aa)
XP_003950026.1 PREDICTED: cullin-3 P. troglodytes 100.0 773
NP_001244127.1 CUL3 gene product H. sapiens 100.0 773
XP_001365428.1 PREDICTED: cullin-3 M. domestica 100.0 767
XP_001109745.1 PREDICTED: cullin-3 isoform 5 M. mulatta 100.0 767
XP_003133733.3 PREDICTED: cullin-3-like S. scrofa 100.0 767
NP_001179735.1 cullin-3 B. taurus 100.0 767
XP_003908063.1 PREDICTED: cullin-3 isoform 1 P. anubis 100.0 766
XP_002198148.1 PREDICTED: cullin-3 T. guttata 100.0 745
XP_534586.2 PREDICTED: cullin-3 isoform 1 C. lupus familiaris 100.0 745
XP_002712552.1 PREDICTED: cullin 3 O. cuniculus 100.0 745
XP_001493416.3 PREDICTED: cullin-3 E. caballus 100.0 743
XP_004005021.1 PREDICTED: cullin-3 O. aries 100.0 652
NP_057925.1 Cul3 gene product M. musculus 99.9 767
XP_003218311.1 PREDICTED: cullin-3-like A. carolinensis 99.9 767
XP_422620.3 PREDICTED: cullin-3, partial G. gallus 99.9 766
NP_001100393.1 cullin-3 R. norvegicus 99.9 745
XP_001512511.2 PREDICTED: cullin-3, partial O. anatinus 99.8 642
XP_003209115.1 PREDICTED: cullin-3-like, partial M. gallopavo 99.8 472
NP_001015975.2 cul3 gene product X. tropicalis 99.6 767
NP_001086652.1 cullin-3-A X. laevis 99.5 767
NP_001177414.1 cul3b gene product D. rerio 99.0 765
NP_523573.1 Cullin-3, isoform C D. melanogaster 76.2 769
NP_174005.1 cullin 3 A. thaliana 58.2 729
NP_503151.1 Protein CUL-3 C. elegans 57.0 776
XP_001700877.1 ubiquitin ligase SCF complex subunit cullin C. reinhardtii 56.6 711
XP_965092.2 hypothetical protein NCU02498 N. crassa 48.0 221
Other hits (2 of 41) [Show all]SpeciesId(%)Len(aa)
XP_003449300.1 PREDICTED: cullin-3-like O. niloticus 99.1 766
XP_004075805.1 PREDICTED: cullin-3-like isoform 1 O. latipes 99.0 766

GENE EXPRESSION
Tissues and development stages from this gene's sequences survey gene expression. Links to other NCBI expression resources.
EST Profile: Approximate expression patterns inferred from EST sources.
[Show more entries with profiles like this]
GEO Profiles: Experimental gene expression data (Gene Expression Omnibus).
cDNA Sources: brain; testis; uncharacterized tissue; mixed; mammary gland; kidney; adrenal gland; placenta; intestine; uterus; eye; liver; lung; pharynx; embryonic tissue; pancreas; thyroid; ovary; spleen; bone; bladder; connective tissue; lymph node; bone marrow; skin; prostate; vascular; heart; blood; stomach; parathyroid; muscle; cervix; trachea; thymus; ascites; mouth; esophagus; pituitary gland
MAPPING POSITION
Genomic location specified by transcript mapping, radiation hybrid mapping, genetic mapping or cytogenetic mapping.
Chromosome: 2
Map position: 2q36.2
UniSTS entry: Chr 2 RH91730
UniSTS entry: Chr 2 D2S1988
UniSTS entry: Chr 2 D2S2605 [Map Viewer]
UniSTS entry: Chr 2 CUL3-1
UniSTS entry: Chr 2 D2S1630E
UniSTS entry: Chr 2 CUL3_313
SEQUENCES
Sequences representing this gene; mRNAs, ESTs, and gene predictions supported by transcribed sequences.

mRNA sequences (17)

AF062537.1 Homo sapiens cullin 3 mRNA, complete cds PA
AB014517.2 Homo sapiens KIAA0617 mRNA for KIAA0617 protein, partial cds P
AF052147.1 Homo sapiens clone 24454 cul-3 mRNA, complete cds PA
AF064087.1 Homo sapiens cullin 3 mRNA, complete cds PA
AY337761.1 Homo sapiens cullin 3 isoform (CUL3) mRNA, complete cds PA
NM_003590.4 Homo sapiens cullin 3 (CUL3), transcript variant 1, mRNA P
BC092409.1 Homo sapiens cullin 3, mRNA (cDNA clone MGC:102838 IMAGE:6168545), complete cds PA
AY007151.1 Homo sapiens clone CDABP0090 mRNA sequence A
AK291151.1 Homo sapiens cDNA FLJ76286 complete cds, highly similar to Homo sapiens cullin 3 (CUL3), mRNA PA
U58089.1 Human Hs-cul-3 mRNA, partial cds PA
AK308496.1 Homo sapiens cDNA, FLJ98537 PA
AK098531.1 Homo sapiens cDNA FLJ25665 fis, clone TST02955 PA
BC031844.1 Homo sapiens cullin 3, mRNA (cDNA clone IMAGE:3861760), partial cds PA
AK299644.1 Homo sapiens cDNA FLJ53180 complete cds, highly similar to Cullin-3 PA
NM_001257197.1 Homo sapiens cullin 3 (CUL3), transcript variant 2, mRNA P
NM_001257198.1 Homo sapiens cullin 3 (CUL3), transcript variant 3, mRNA P
BC039598.1 Homo sapiens cullin 3, mRNA (cDNA clone MGC:48882 IMAGE:5784147), complete cds PA

EST sequences (10 of 500) [Show all sequences]

AA888221.1 Clone IMAGE:1492277 kidney 3' read A
AA968617.1 Clone IMAGE:1578355 mixed 3' read A
AA976035.1 Clone IMAGE:1587776 uncharacterized tissue 3' read A
AA994964.1 Clone IMAGE:1634963 kidney 3' read PA
AI026975.1 Clone IMAGE:1649359 parathyroid 3' read A
R21388.1 Clone IMAGE:35992 brain 5' read
AI089963.1 Clone IMAGE:1687356 brain 3' read PA
AA921697.1 Clone IMAGE:1536910 kidney 3' read A
AI129514.1 Clone IMAGE:1711530 uterus 3' read A
AI084250.1 Clone IMAGE:1668245 parathyroid 3' read A


Key to Symbols

P Has similarity to known Proteins (after translation)
A Contains a poly-Adenylation signal
S Sequence is a Suboptimal member of this cluster
M Clone is putatively CDS-complete by MGC criteria

 
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