> ATPase, Na+/K+ transporting, alpha 1 polypeptide (ATP1A1)
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UGID:199560     UniGene Hs.371889     Homo sapiens (human)   ATP1A1 Order cDNA clone, Links
ATPase, Na+/K+ transporting, alpha 1 polypeptide (ATP1A1)

Human protein-coding gene ATP1A1. Represented by 3353 ESTs from 721 cDNA libraries. Corresponds to 3 reference sequences (different isoforms). [UniGene 199560 - Hs.371889]

SELECTED PROTEIN SIMILARITIES
Comparison of cluster transcripts with RefSeq proteins. The alignments can suggest function of the cluster.
Best Hits and Hits from model organismsSpeciesId(%)Len(aa)
XP_001112674.1 PREDICTED: sodium/potassium-transporting ATPase subunit alpha-1 isoform 3 M. mulatta 100.0 1022
XP_513679.3 PREDICTED: sodium/potassium-transporting ATPase subunit alpha-1 P. troglodytes 100.0 1022
NP_000692.2 ATP1A1 gene product H. sapiens 100.0 1022
XP_003892516.1 PREDICTED: sodium/potassium-transporting ATPase subunit alpha-1 P. anubis 99.9 994
NP_999414.1 ATP1A1 gene product S. scrofa 99.7 1020
NP_001070266.1 ATP1A1 gene product B. taurus 99.6 1020
NP_001009360.1 ATP1A1 gene product O. aries 99.6 1020
NP_659149.1 Atp1a1 gene product M. musculus 99.0 1022
NP_001084064.1 sodium/potassium-transporting ATPase subunit alpha-1 X. laevis 96.6 1024
NP_571761.1 atp1a1 gene product D. rerio 94.2 1027
NP_996247.1 Na pump alpha subunit, isoform H D. melanogaster 87.7 999
NP_506269.1 Protein EAT-6 C. elegans 84.7 994
XP_001696293.1 sodium/potassium-transporting ATPase alpha subunit C. reinhardtii 55.8 893
NP_563860.1 Ca2+-transporting ATPase A. thaliana 48.8 172
XP_956354.1 calcium-transporting ATPase 3 N. crassa 45.9 181
Other hits (2 of 52) [Show all]SpeciesId(%)Len(aa)
NP_001156546.1 ATP1A1 gene product O. cuniculus 99.4 1022
NP_001003306.1 ATP1A1 gene product C. lupus familiaris 99.2 1020

GENE EXPRESSION
Tissues and development stages from this gene's sequences survey gene expression. Links to other NCBI expression resources.
EST Profile: Approximate expression patterns inferred from EST sources.
[Show more entries with profiles like this]
GEO Profiles: Experimental gene expression data (Gene Expression Omnibus).
cDNA Sources: brain; skin; testis; intestine; ovary; prostate; kidney; pancreas; lung; uterus; thyroid; mammary gland; embryonic tissue; placenta; uncharacterized tissue; eye; liver; stomach; mixed; trachea; mouth; blood; connective tissue; bone; muscle; thymus; ascites; adrenal gland; bladder; lymph; larynx; vascular; nerve; parathyroid; spleen; lymph node; umbilical cord; cervix; heart; adipose tissue; amniotic fluid; pituitary gland; pharynx; bone marrow; ganglia; esophagus; salivary gland; pineal gland; epididymis
MAPPING POSITION
Genomic location specified by transcript mapping, radiation hybrid mapping, genetic mapping or cytogenetic mapping.
Chromosome: 1
Map position: 1p21
UniSTS entry: Chr 1 RH17421 [Map Viewer]
UniSTS entry: Chr 1 D1S1924E
UniSTS entry: Chr 1 A001Z44 [Map Viewer]
UniSTS entry: Chr 1 D1S3311
UniSTS entry: Chr 1 D1S3017
UniSTS entry: Chr 1 AL009633
UniSTS entry: Chr 11 RH46547
UniSTS entry: Chr 11 RH12529 [Map Viewer]
UniSTS entry: RH91445
UniSTS entry: GDB:452619
SEQUENCES
Sequences representing this gene; mRNAs, ESTs, and gene predictions supported by transcribed sequences.

mRNA sequences (15)

BC050359.1 Homo sapiens ATPase, Na+/K+ transporting, alpha 1 polypeptide, mRNA (cDNA clone MGC:51750 IMAGE:6065209), complete cds PA
NM_000701.7 Homo sapiens ATPase, Na+/K+ transporting, alpha 1 polypeptide (ATP1A1), transcript variant 1, mRNA PA
AY946013.1 Homo sapiens Na+/K+ transporting ATPase alpha 1 polypeptide (ATP1A1) mRNA, partial cds
BC001330.1 Homo sapiens, clone IMAGE:3457513, mRNA, partial cds PA
BC003077.2 Homo sapiens ATPase, Na+/K+ transporting, alpha 1 polypeptide, mRNA (cDNA clone MGC:3285 IMAGE:3507685), complete cds PA
U16798.1 Human Na,K-ATPase alpha-1 subunit mRNA, complete cds P
AK308418.1 Homo sapiens cDNA, FLJ98366 P
AK314777.1 Homo sapiens cDNA, FLJ95647, highly similar to Homo sapiens ATPase, Na+/K+ transporting, alpha 1 polypeptide (ATP1A1), mRNA P
J03007.1 Human Na+,K+ ATPase alpha-subunit mRNA, partial cds P
AK296384.1 Homo sapiens cDNA FLJ60077 partial cds, highly similar to Sodium/potassium-transporting ATPase alpha-1 chain precursor (EC 3.6.3.9) PA
AK296362.1 Homo sapiens cDNA FLJ52430 complete cds, highly similar to Sodium/potassium-transporting ATPase alpha-1 chain precursor (EC 3.6.3.9) P
AK295095.1 Homo sapiens cDNA FLJ55427 complete cds, highly similar to Sodium/potassium-transporting ATPase alpha-1 chain precursor (EC 3.6.3.9) P
AK293689.1 Homo sapiens cDNA FLJ53830 complete cds, highly similar to Sodium/potassium-transporting ATPase alpha-1 chain precursor (EC 3.6.3.9) PA
NM_001160234.1 Homo sapiens ATPase, Na+/K+ transporting, alpha 1 polypeptide (ATP1A1), transcript variant 4, mRNA PA
NM_001160233.1 Homo sapiens ATPase, Na+/K+ transporting, alpha 1 polypeptide (ATP1A1), transcript variant 3, mRNA PA

EST sequences (10 of 3353) [Show all sequences]

AA972529.1 Clone IMAGE:1435477 intestine 3' read A
AA975936.1 Clone IMAGE:1567995 lung 3' read P
AA984376.1 Clone IMAGE:1629877 brain 3' read P
AA984433.1 Clone IMAGE:1630006 brain 3' read
AA984644.1 Clone IMAGE:1630038 brain 3' read P
AA987203.1 Clone IMAGE:1603287 lung 3' read A
AA987775.1 Clone IMAGE:1601681 lung 3' read A
AA989683.1 Clone IMAGE:1577568 spleen 3' read A
AA991293.1 Clone IMAGE:1608864 mammary gland 3' read A
AA994455.1 Clone IMAGE:1628592 mixed 3' read P


Key to Symbols

P Has similarity to known Proteins (after translation)
A Contains a poly-Adenylation signal
S Sequence is a Suboptimal member of this cluster
M Clone is putatively CDS-complete by MGC criteria

 
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