Crystallin, beta B1 (CRYBB1)

Restricted Expression:

soft tissue/muscle tissue tumor [show more like this]

EST Profile:

Approximate expression patterns inferred from EST sources.
[Show more entries with profiles like this]

GEO Profiles:

Experimental gene expression data (Gene Expression Omnibus).

cDNA Sources:

eye; connective tissue; uncharacterized tissue; mixed; embryonic tissue; lung; placenta; brain; lymph node

NCBI

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Finding cDNAs

UGID:136508 UniGene Hs.37135 Homo sapiens (human) CRYBB1

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Crystallin, beta B1 (CRYBB1)

Human protein-coding gene CRYBB1. Represented by 169 ESTs from 30 cDNA libraries. EST representation biased toward soft tissue/muscle tissue tumor. Corresponds to reference sequence NM_001887.3. [UniGene 136508 - Hs.37135]

SELECTED PROTEIN SIMILARITIES

Comparison of cluster transcripts with RefSeq proteins. The alignments can suggest function of the cluster.

Best Hits and Hits from model organisms		Species	Id(%)	Len(aa)
NP_001878.1 Conserved domains (CDD) Gene summary Protein sequence Protein/EST matches (ProtEST) Protein/protein matches (BLink)	CRYBB1 gene product	H. sapiens	100.0	251
XP_001172375.2 Conserved domains (CDD) Gene summary Protein sequence Protein/EST matches (ProtEST) Protein/protein matches (BLink)	PREDICTED: beta-crystallin B1 isoform 1	P. troglodytes	99.6	251
NP_076184.1 Conserved domains (CDD) Gene summary Protein sequence Protein/EST matches (ProtEST) Protein/protein matches (BLink)	beta-crystallin B1	M. musculus	84.8	249
NP_001081242.1 Conserved domains (CDD) Gene summary Protein sequence Protein/EST matches (ProtEST) Protein/protein matches (BLink)	crystallin, beta B1	X. laevis	71.2	218
NP_775338.2 Conserved domains (CDD) Gene summary Protein sequence Protein/EST matches (ProtEST) Protein/protein matches (BLink)	crybb1 gene product	D. rerio	69.3	231
Other hits (2 of 21) [Show all]		Species	Id(%)	Len(aa)
XP_002798364.1 Conserved domains (CDD) Gene summary Protein sequence Protein/EST matches (ProtEST) Protein/protein matches (BLink)	PREDICTED: beta-crystallin B1-like, partial	M. mulatta	95.9	242
XP_003905407.1 Conserved domains (CDD) Gene summary Protein sequence Protein/EST matches (ProtEST) Protein/protein matches (BLink)	PREDICTED: beta-crystallin B1	P. anubis	95.2	251

GENE EXPRESSION

Tissues and development stages from this gene's sequences survey gene expression. Links to other NCBI expression resources.

MAPPING POSITION

Genomic location specified by transcript mapping, radiation hybrid mapping, genetic mapping or cytogenetic mapping.

Chromosome:	22
Map position:	22q12.1
UniSTS entry:	Chr 22	RH71225	[Map Viewer]

SEQUENCES

Sequences representing this gene; mRNAs, ESTs, and gene predictions supported by transcribed sequences.

mRNA sequences (4)

NM_001887.3	Homo sapiens crystallin, beta B1 (CRYBB1), mRNA	P
CR456425.1	Homo sapiens CRYBB1 full length open reading frame (ORF) cDNA clone (cDNA clone C22ORF:pGEM.CRYBB1)	P
U35340.1	Homo sapiens beta B1-crystallin mRNA, complete cds	P
BC036790.1	Homo sapiens crystallin, beta B1, mRNA (cDNA clone MGC:45992 IMAGE:5752689), complete cds	PA

EST sequences (10 of 169) [Show all sequences]

AA973336.1	Clone IMAGE:1584241	mixed	3' read	PA
AA976606.1	Clone IMAGE:1585249	lung	3' read	P
AA987773.1	Clone IMAGE:1601677	lung	3' read	PA
AA928954.1	Clone IMAGE:1567809	lung	3' read	A
AI087967.1	Clone IMAGE:1567132	mixed	3' read	PA
AI142108.1	Clone IMAGE:1651341	mixed	3' read	PA
CB054561.1	Clone IMAGE:3291528	brain	5' read	P
AI339376.1	Clone IMAGE:1947705	uncharacterized tissue	3' read	PA
AI699128.1	Clone IMAGE:2273614	lung	3' read	A
AI699613.1	Clone IMAGE:2241130	uncharacterized tissue	3' read	A

Key to Symbols

P Has similarity to known Proteins (after translation)
A Contains a poly-Adenylation signal
S Sequence is a Suboptimal member of this cluster
M Clone is putatively CDS-complete by MGC criteria