> Exportin 1 (CRM1 homolog, yeast) (XPO1)
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UGID:198866     UniGene Hs.370770     Homo sapiens (human)   XPO1 Order cDNA clone, Links
Exportin 1 (CRM1 homolog, yeast) (XPO1)

Human protein-coding gene XPO1. Represented by 979 ESTs from 344 cDNA libraries. Corresponds to reference sequence NM_003400.3. [UniGene 198866 - Hs.370770]

SELECTED PROTEIN SIMILARITIES
Comparison of cluster transcripts with RefSeq proteins. The alignments can suggest function of the cluster.
Best Hits and Hits from model organismsSpeciesId(%)Len(aa)
XP_001115623.1 PREDICTED: exportin-1-like isoform 3 M. mulatta 100.0 1070
XP_003908752.1 PREDICTED: exportin-1 isoform 1 P. anubis 100.0 1070
XP_001161367.1 PREDICTED: exportin-1 isoform 5 P. troglodytes 100.0 1070
NP_003391.1 XPO1 gene product H. sapiens 100.0 1070
XP_003203660.1 PREDICTED: hypothetical protein LOC100538567, partial M. gallopavo 100.0 159
XP_531839.2 PREDICTED: exportin-1 isoform 1 C. lupus familiaris 99.7 1070
XP_001917538.1 PREDICTED: exportin-1-like E. caballus 99.7 1070
NP_001179190.1 exportin-1 B. taurus 99.7 1070
XP_004005904.1 PREDICTED: exportin-1 isoform 1 O. aries 99.7 1070
XP_002709898.1 PREDICTED: exportin 1 O. cuniculus 99.7 1070
XP_001512501.2 PREDICTED: exportin-1-like O. anatinus 99.7 1026
XP_003227812.1 PREDICTED: exportin-1-like A. carolinensis 99.6 1070
NP_001012887.2 exportin-1 G. gallus 99.6 1070
XP_003354851.2 PREDICTED: exportin-1 S. scrofa 99.6 976
XP_001375031.1 PREDICTED: exportin-1-like M. domestica 99.5 1070
XP_002199319.1 PREDICTED: exportin-1 T. guttata 99.5 1070
NP_598775.2 Xpo1 gene product M. musculus 99.4 1070
NP_001083734.1 exportin 1 (CRM1 homolog) X. laevis 99.0 1070
XP_001919797.2 PREDICTED: exportin-1 D. rerio 98.0 1070
NP_723391.2 embargoed D. melanogaster 80.2 1060
NP_741567.1 Protein XPO-1, isoform a C. elegans 65.1 1076
XP_955917.2 exportin-1 N. crassa 64.7 1074
XP_001695594.1 exportin C. reinhardtii 61.0 1057
NP_566193.2 exportin 1B A. thaliana 60.3 1074
NP_011734.3 Crm1p S. cerevisiae 57.5 1080
Other hits (2 of 48) [Show all]SpeciesId(%)Len(aa)
NP_445942.1 Xpo1 gene product R. norvegicus 99.3 1070
XP_002939551.1 PREDICTED: exportin-1 X. tropicalis 99.3 1070

GENE EXPRESSION
Tissues and development stages from this gene's sequences survey gene expression. Links to other NCBI expression resources.
EST Profile: Approximate expression patterns inferred from EST sources.
[Show more entries with profiles like this]
GEO Profiles: Experimental gene expression data (Gene Expression Omnibus).
cDNA Sources: brain; testis; embryonic tissue; uncharacterized tissue; uterus; placenta; lung; liver; heart; adrenal gland; muscle; thymus; skin; intestine; kidney; pharynx; mammary gland; pituitary gland; eye; bone marrow; adipose tissue; mouth; pancreas; trachea; prostate; lymph node; blood; stomach; ovary; vascular; spleen; cervix; esophagus; mixed; salivary gland; parathyroid; ascites; connective tissue; nerve; bone; bladder; thyroid; lymph; ear; larynx; ganglia; pineal gland; tonsil
MAPPING POSITION
Genomic location specified by transcript mapping, radiation hybrid mapping, genetic mapping or cytogenetic mapping.
Chromosome: 2
Map position: 2p15
UniSTS entry: Chr 2 RH12025
UniSTS entry: Chr 2 RH46337
UniSTS entry: Chr 1 D11S2560
UniSTS entry: Chr 1 L17705
UniSTS entry: Chr 1 D1S1423
UniSTS entry: Chr 1 GDB:434012
UniSTS entry: Chr 1 D11S3114
UniSTS entry: Chr 1 D8S2279
UniSTS entry: Chr 1 sY3084
UniSTS entry: Chr 2 RH80312
SEQUENCES
Sequences representing this gene; mRNAs, ESTs, and gene predictions supported by transcribed sequences.

mRNA sequences (14)

BX647758.1 Homo sapiens mRNA; cDNA DKFZp686K0731 (from clone DKFZp686K0731) PA
AK124769.1 Homo sapiens cDNA FLJ42779 fis, clone BRAWH3005300, highly similar to Exportin-1 P
NM_003400.3 Homo sapiens exportin 1 (CRM1 homolog, yeast) (XPO1), mRNA P
CR749840.1 Homo sapiens mRNA; cDNA DKFZp686B1823 (from clone DKFZp686B1823) PA
AK289920.1 Homo sapiens cDNA FLJ78427 complete cds, highly similar to Homo sapiens exportin 1 (CRM1 homolog, yeast) (XPO1), mRNA P
AK312426.1 Homo sapiens cDNA, FLJ92769 P
AK098297.1 Homo sapiens cDNA FLJ40978 fis, clone UTERU2014223
AK094339.1 Homo sapiens cDNA FLJ37020 fis, clone BRACE2010684, highly similar to Rattus norvegicus mRNA for CRM1 protein P
AL833550.1 Homo sapiens mRNA; cDNA DKFZp686O173 (from clone DKFZp686O173) PA
AK299039.1 Homo sapiens cDNA FLJ55480 complete cds, highly similar to Exportin-1 P
AK316481.1 Homo sapiens cDNA, FLJ79380 complete cds, highly similar to Exportin-1 P
BC032847.2 Homo sapiens exportin 1 (CRM1 homolog, yeast), mRNA (cDNA clone MGC:33022 IMAGE:5267242), complete cds PA
Y08614.2 Homo sapiens mRNA for CRM1 protein PA
D89729.1 Homo sapiens mRNA for CRM1 protein, complete cds P

EST sequences (10 of 979) [Show all sequences]

AA954619.1 Clone IMAGE:1572782 kidney 3' read A
AA962589.1 Clone IMAGE:1597781 uncharacterized tissue 3' read A
AI003860.1 Clone IMAGE:1621745 testis 3' read A
AI049666.1 Clone IMAGE:1700434 kidney 3' read A
AI092783.1 Clone IMAGE:1693100 heart 3' read A
AI125540.1 Clone IMAGE:1737113 testis 3' read
CB044531.1 Clone IMAGE:3217818 intestine 3' read A
CB044532.1 Clone IMAGE:3217818 intestine 5' read P
AI150320.1 Clone IMAGE:1752489 testis 3' read A
AI151017.1 Clone IMAGE:1703719 brain 3' read A


Key to Symbols

P Has similarity to known Proteins (after translation)
A Contains a poly-Adenylation signal
S Sequence is a Suboptimal member of this cluster
M Clone is putatively CDS-complete by MGC criteria

 
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