Calcitonin-related polypeptide alpha (CALCA)

Restricted Expression:

thyroid [show more like this]

head and neck tumor [show more like this]

EST Profile:

Approximate expression patterns inferred from EST sources.
[Show more entries with profiles like this]

GEO Profiles:

Experimental gene expression data (Gene Expression Omnibus).

cDNA Sources:

thyroid; uncharacterized tissue; prostate; pineal gland; brain; mixed

NCBI

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Finding cDNAs

UGID:136494 UniGene Hs.37058 Homo sapiens (human) CALCA

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Calcitonin-related polypeptide alpha (CALCA)

Human protein-coding gene CALCA. Represented by 35 ESTs from 6 cDNA libraries. EST representation biased toward thyroid; head and neck tumor. Corresponds to 3 reference sequences (different isoforms). [UniGene 136494 - Hs.37058]

SELECTED PROTEIN SIMILARITIES

Comparison of cluster transcripts with RefSeq proteins. The alignments can suggest function of the cluster.

Best Hits and Hits from model organisms		Species	Id(%)	Len(aa)
NP_001732.1 Conserved domains (CDD) Gene summary Protein sequence Protein/EST matches (ProtEST) Protein/protein matches (BLink)	CALCA gene product	H. sapiens	100.0	140
NP_031613.2 Conserved domains (CDD) Gene summary Protein sequence Protein/EST matches (ProtEST) Protein/protein matches (BLink)	Calca gene product	M. musculus	76.7	133
Other hits (2 of 10) [Show all]		Species	Id(%)	Len(aa)
XP_003312978.1 Conserved domains (CDD) Gene summary Protein sequence Protein/EST matches (ProtEST) Protein/protein matches (BLink)	PREDICTED: calcitonin isoform 3	P. troglodytes	98.6	140
XP_001088995.2 Conserved domains (CDD) Gene summary Protein sequence Protein/EST matches (ProtEST) Protein/protein matches (BLink)	PREDICTED: calcitonin-like	M. mulatta	93.6	139

GENE EXPRESSION

Tissues and development stages from this gene's sequences survey gene expression. Links to other NCBI expression resources.

MAPPING POSITION

Genomic location specified by transcript mapping, radiation hybrid mapping, genetic mapping or cytogenetic mapping.

Chromosome:	11
Map position:	11p15.2
UniSTS entry:	Chr 11	D11S4427	[Map Viewer]
UniSTS entry:	Chr 11	G06648

SEQUENCES

Sequences representing this gene; mRNAs, ESTs, and gene predictions supported by transcribed sequences.

mRNA sequences (17)

NM_001741.2	Homo sapiens calcitonin-related polypeptide alpha (CALCA), transcript variant 1, mRNA	PA
BC069760.1	Homo sapiens calcitonin-related polypeptide alpha, mRNA (cDNA clone MGC:97244 IMAGE:7262493), complete cds	P
BC069704.1	Homo sapiens calcitonin-related polypeptide alpha, mRNA (cDNA clone MGC:97232 IMAGE:7262481), complete cds	P
BC069684.1	Homo sapiens calcitonin-related polypeptide alpha, mRNA (cDNA clone MGC:97315 IMAGE:7262564), complete cds	P
BC069778.1	Homo sapiens calcitonin-related polypeptide alpha, mRNA (cDNA clone MGC:97256 IMAGE:7262505), complete cds	P
BC093753.1	Homo sapiens calcitonin-related polypeptide alpha, mRNA (cDNA clone MGC:120788 IMAGE:7939598), complete cds	P
M64486.1	Human calcitonin (CALCA) mRNA, complete cds	P
BC101599.1	Homo sapiens calcitonin-related polypeptide alpha, mRNA (cDNA clone MGC:126648 IMAGE:8069105), complete cds	P
NM_001033952.2	Homo sapiens calcitonin-related polypeptide alpha (CALCA), transcript variant 2, mRNA	PA
NM_001033953.2	Homo sapiens calcitonin-related polypeptide alpha (CALCA), transcript variant 3, mRNA	P
X03662.1	Human BEN lung carcinoma cell line mRNA for high-M(r) calcitonin	P
X00356.1	Human calcitonin precursor mRNA Calcitonin (CT) is a hypocalcemic hypophosphatemic hormone	P
X02330.1	Homo sapiens mRNA for calcitonin and calcitonin gene related peptide (CGRP)	P
K03513.1	Human calcitonin mRNA, partial
K03512.1	Human calcitonin gene related peptide mRNA, partial cds
BC143562.1	Homo sapiens calcitonin-related polypeptide alpha, mRNA (cDNA clone MGC:177090 IMAGE:9052073), complete cds	P
M26095.1	Human calcitonin mRNA, complete cds	P

EST sequences (10 of 35) [Show all sequences]

CB048117.1	Clone IMAGE:3270432	prostate	3' read	A
CB048118.1	Clone IMAGE:3270432	prostate	5' read	A
BX094781.1	Clone IMAGp998J115574_;_IMAGE:2252266	prostate
AI695720.1	Clone IMAGE:2252266	prostate	3' read
CD612753.1		uncharacterized tissue
CD612754.1		uncharacterized tissue
CD612755.1		uncharacterized tissue
CD612756.1		uncharacterized tissue
CD612757.1		uncharacterized tissue
CD612758.1		uncharacterized tissue

Key to Symbols

P Has similarity to known Proteins (after translation)
A Contains a poly-Adenylation signal
S Sequence is a Suboptimal member of this cluster
M Clone is putatively CDS-complete by MGC criteria