> B-cell CLL/lymphoma 11A (zinc finger protein) (BCL11A)
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UGID:198744     UniGene Hs.370549     Homo sapiens (human)   BCL11A
B-cell CLL/lymphoma 11A (zinc finger protein) (BCL11A)

Human protein-coding gene BCL11A. Represented by 186 ESTs from 82 cDNA libraries. Corresponds to 3 reference sequences (different isoforms). [UniGene 198744 - Hs.370549]

SELECTED PROTEIN SIMILARITIES
Comparison of cluster transcripts with RefSeq proteins. The alignments can suggest function of the cluster.
Best Hits and Hits from model organismsSpeciesId(%)Len(aa)
NP_075044.2 BCL11A gene product H. sapiens 100.0 834
XP_001158392.2 PREDICTED: b-cell lymphoma/leukemia 11A isoform 5 P. troglodytes 100.0 792
XP_003125157.1 PREDICTED: B-cell lymphoma/leukemia 11A isoform 1 S. scrofa 100.0 772
XP_003908733.1 PREDICTED: B-cell lymphoma/leukemia 11A P. anubis 100.0 682
XP_001917590.2 PREDICTED: b-cell lymphoma/leukemia 11A-like E. caballus 100.0 242
NP_001229863.1 Bcl11a gene product M. musculus 99.9 834
XP_865555.2 PREDICTED: B-cell lymphoma/leukemia 11A isoform 4 C. lupus familiaris 99.9 792
XP_002709742.1 PREDICTED: B-cell CLL/lymphoma 11A O. cuniculus 99.8 817
XP_223693.5 PREDICTED: B-cell CLL/lymphoma 11A (zinc finger protein) isoform 2 R. norvegicus 99.6 834
NP_001083346.1 B-cell CLL/lymphoma 11A (zinc finger protein) X. laevis 94.2 725
NP_001035481.1 bcl11aa gene product D. rerio 82.6 828
NP_727173.2 CG9650, isoform I D. melanogaster 74.5 102
Other hits (2 of 27) [Show all]SpeciesId(%)Len(aa)
XP_003339777.1 PREDICTED: LOW QUALITY PROTEIN: b-cell lymphoma/leukemia 11A-like M. domestica 98.0 811
NP_001026202.1 BCL11A gene product G. gallus 97.6 795

GENE EXPRESSION
Tissues and development stages from this gene's sequences survey gene expression. Links to other NCBI expression resources.
EST Profile: Approximate expression patterns inferred from EST sources.
[Show more entries with profiles like this]
GEO Profiles: Experimental gene expression data (Gene Expression Omnibus).
cDNA Sources: brain; lymph node; mixed; uncharacterized tissue; lung; embryonic tissue; uterus; prostate; blood; pancreas; skin; placenta; larynx; mouth; thymus; intestine; kidney; testis; connective tissue; lymph; ovary; esophagus; parathyroid; eye; heart; mammary gland
MAPPING POSITION
Genomic location specified by transcript mapping, radiation hybrid mapping, genetic mapping or cytogenetic mapping.
Chromosome: 2
Map position: 2p16.1
UniSTS entry: Chr 2 RH94052
UniSTS entry: Chr 2 Bcl11a
UniSTS entry: Bcl11a
UniSTS entry: Bcl11a
UniSTS entry: Chr 1 G35510
UniSTS entry: SHGC-60172
SEQUENCES
Sequences representing this gene; mRNAs, ESTs, and gene predictions supported by transcribed sequences.

mRNA sequences (18)

AY228763.1 Homo sapiens B-cell CLL/lymphoma 11A isoform 6 (BCL11A) mRNA, complete cds P
AK125704.1 Homo sapiens cDNA FLJ43716 fis, clone TESOP2005498
AK001035.1 Homo sapiens cDNA FLJ10173 fis, clone HEMBA1003953 P
AY692278.1 Homo sapiens B-cell lymphoma/leukaemia 11A extra-short form (BCL11A) mRNA, complete cds, alternatively spliced P
NM_018014.3 Homo sapiens B-cell CLL/lymphoma 11A (zinc finger protein) (BCL11A), transcript variant 2, mRNA PA
AJ404611.1 Homo sapiens mRNA for B-cell lymphoma/leukaemia 11A extra long form (BCL11A-XL gene) PA
AJ404612.1 Homo sapiens mRNA for B-cell lymphoma/leukaemia 11A long form (BCL11A-L gene) PA
AJ404613.1 Homo sapiens mRNA for B-cell lymphoma/leukaemia 11A short form (BCL11A-S gene) PA
AF080216.1 Homo sapiens C2H2-type zinc-finger protein mRNA, complete cds PA
NM_022893.3 Homo sapiens B-cell CLL/lymphoma 11A (zinc finger protein) (BCL11A), transcript variant 1, mRNA PA
AB058712.1 Homo sapiens mRNA for KIAA1809 protein, partial cds P
AK055251.1 Homo sapiens cDNA FLJ30689 fis, clone FCBBF2000566, highly similar to B-cell lymphoma/leukemia 11A PA
BC021098.1 Homo sapiens B-cell CLL/lymphoma 11A (zinc finger protein), mRNA (cDNA clone MGC:31810 IMAGE:5087967), complete cds PA
NM_138559.1 Homo sapiens B-cell CLL/lymphoma 11A (zinc finger protein) (BCL11A), transcript variant 3, mRNA PA
AK092316.1 Homo sapiens cDNA FLJ34997 fis, clone OCBBF2011625, highly similar to B-cell lymphoma/leukemia 11A P
AK300012.1 Homo sapiens cDNA FLJ57865 complete cds, highly similar to B-cell lymphoma/leukemia 11A PA
AK297507.1 Homo sapiens cDNA FLJ58516 complete cds, highly similar to B-cell lymphoma/leukemia 11A P
JN852960.1 Homo sapiens BCL11a-M (BCL11A) mRNA, partial cds, alternatively spliced P

EST sequences (10 of 186) [Show all sequences]

AA947948.1 Clone IMAGE:1416013 lung 3' read A
AA971704.1 Clone IMAGE:1584563 lung 3' read A
AI081350.1 Clone IMAGE:1662278 mixed 3' read P
AI146836.1 Clone IMAGE:1707606 heart 3' read A
BX094281.1 Clone IMAGp998I16581_;_IMAGE:265431 skin
AI254609.1 Clone IMAGE:1985411 ovary 3' read
AI266047.1 Clone IMAGE:1932265 mixed 3' read A
AI277234.1 Clone IMAGE:1893724 placenta 3' read
AI290171.1 Clone IMAGE:1879136 mixed 3' read A
AI290172.1 Clone IMAGE:1879138 mixed 3' read A


Key to Symbols

P Has similarity to known Proteins (after translation)
A Contains a poly-Adenylation signal
S Sequence is a Suboptimal member of this cluster
M Clone is putatively CDS-complete by MGC criteria

 
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