> Hexokinase 1 (HK1)
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UGID:198626     UniGene Hs.370365     Homo sapiens (human)   HK1 Order cDNA clone, Links
Hexokinase 1 (HK1)

Human protein-coding gene HK1. Represented by 635 ESTs from 275 cDNA libraries. Corresponds to 5 reference sequences (different isoforms). [UniGene 198626 - Hs.370365]

SELECTED PROTEIN SIMILARITIES
Comparison of cluster transcripts with RefSeq proteins. The alignments can suggest function of the cluster.
Best Hits and Hits from model organismsSpeciesId(%)Len(aa)
NP_277032.1 HK1 gene product H. sapiens 100.0 920
XP_507830.2 PREDICTED: hexokinase-1 isoform 10 P. troglodytes 100.0 915
XP_001110396.2 PREDICTED: hexokinase-1-like isoform 6 M. mulatta 99.8 919
XP_003903895.1 PREDICTED: hexokinase-1 isoform 2 P. anubis 99.8 919
NP_001139572.1 Hk1 gene product M. musculus 96.3 917
NP_001096656.1 hexokinase 1 X. laevis 89.3 914
NP_998417.1 hk1 gene product D. rerio 88.9 916
NP_727350.1 hexokinase A, isoform B D. melanogaster 54.7 439
NP_001021107.1 Protein F14B4.2, isoform b C. elegans 53.5 452
NP_179576.1 hexokinase 2 A. thaliana 45.2 210
Other hits (2 of 49) [Show all]SpeciesId(%)Len(aa)
XP_536376.3 PREDICTED: hexokinase-1 C. lupus familiaris 97.5 916
XP_001918031.1 PREDICTED: hexokinase-1 E. caballus 97.3 914

GENE EXPRESSION
Tissues and development stages from this gene's sequences survey gene expression. Links to other NCBI expression resources.
EST Profile: Approximate expression patterns inferred from EST sources.
[Show more entries with profiles like this]
GEO Profiles: Experimental gene expression data (Gene Expression Omnibus).
cDNA Sources: brain; lung; skin; testis; mammary gland; embryonic tissue; uncharacterized tissue; eye; intestine; placenta; bone; thymus; pituitary gland; blood; muscle; uterus; mixed; thyroid; pancreas; lymph; amniotic fluid; adrenal gland; epididymis; tonsil; spleen; bladder; ear; parathyroid; ascites; liver; ovary; kidney; connective tissue; lymph node; prostate; mouth; larynx; heart; bone marrow; vascular; pineal gland; ganglia; stomach
MAPPING POSITION
Genomic location specified by transcript mapping, radiation hybrid mapping, genetic mapping or cytogenetic mapping.
Chromosome: 10
Map position: 10q22
UniSTS entry: Chr 10 STS-M75126 [Map Viewer]
UniSTS entry: Chr 10 SHGC-35892 [Map Viewer]
UniSTS entry: Chr 10 STS-W37533 [Map Viewer]
UniSTS entry: Chr 10 HK1
UniSTS entry: SHGC-132554
UniSTS entry: Chr 4 D1S3696
SEQUENCES
Sequences representing this gene; mRNAs, ESTs, and gene predictions supported by transcribed sequences.

mRNA sequences (19)

AK128226.1 Homo sapiens cDNA FLJ46359 fis, clone TESTI4049786, highly similar to Hexokinase-1 (EC 2.7.1.1) P
NM_000188.2 Homo sapiens hexokinase 1 (HK1), nuclear gene encoding mitochondrial protein, transcript variant 1, mRNA PA
M75126.1 Homo sapiens hexokinase 1 (HK1) mRNA, complete cds P
AB209526.1 Homo sapiens mRNA for hexokinase 1 isoform HKI variant protein P
X66957.1 H. sapiens hexokinase I (MK-16) PA
BC008730.2 Homo sapiens hexokinase 1, mRNA (cDNA clone MGC:1724 IMAGE:3163058), complete cds PA
BC128210.1 Homo sapiens cDNA clone IMAGE:40114447 P
NM_033496.2 Homo sapiens hexokinase 1 (HK1), nuclear gene encoding mitochondrial protein, transcript variant 2, mRNA PA
NM_033497.2 Homo sapiens hexokinase 1 (HK1), nuclear gene encoding mitochondrial protein, transcript variant 3, mRNA PA
NM_033498.2 Homo sapiens hexokinase 1 (HK1), nuclear gene encoding mitochondrial protein, transcript variant 4, mRNA PA
NM_033500.2 Homo sapiens hexokinase 1 (HK1), nuclear gene encoding mitochondrial protein, transcript variant 5, mRNA PA
AK292012.1 Homo sapiens cDNA FLJ78173 complete cds, highly similar to Homo sapiens hexokinase 1 (HK1) mRNA P
AK309904.1 Homo sapiens cDNA, FLJ99945 P
AK091267.1 Homo sapiens cDNA FLJ33948 fis, clone CTONG2018379, highly similar to Hexokinase-1 (EC 2.7.1.1) P
AK294428.1 Homo sapiens cDNA FLJ56506 complete cds, highly similar to Hexokinase-1 (EC 2.7.1.1) P
AF073786.2 Homo sapiens testis-specific hexokinase 1 mRNA, partial cds P
U38228.1 Human testis-specific hexokinase 1 (hHK1-tc) mRNA, partial cds
U38227.1 Human testis-specific hexokinase 1 (hHK1-tb) mRNA, partial cds
U38226.1 Human testis-specific hexokinase 1 (hHK1-ta) mRNA, partial cds

EST sequences (10 of 635) [Show all sequences]

AI003018.1 Clone IMAGE:1684258 brain 3' read P
AI022929.1 Clone IMAGE:1651746 skin 3' read A
R20068.1 Clone IMAGE:35015 brain 5' read P
AI096698.1 Clone IMAGE:1707458 heart 3' read
CB044594.1 Clone IMAGE:3217956 intestine 3' read A
BX107926.1 Clone IMAGp998P17697_;_IMAGE:310144 skin P
CB161166.1 Clone L18POOL1n1-16-D10 liver 5' read
CB120520.1 Clone L8SCK0-35-F06 liver 5' read
CB121976.1 Clone L8SCK0-15-C04 liver 5' read
AI285262.1 Clone IMAGE:1874594 intestine 3' read


Key to Symbols

P Has similarity to known Proteins (after translation)
A Contains a poly-Adenylation signal
S Sequence is a Suboptimal member of this cluster
M Clone is putatively CDS-complete by MGC criteria

 
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