> Tankyrase, TRF1-interacting ankyrin-related ADP-ribose polymerase (TNKS)
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UGID:198563     UniGene Hs.370267     Homo sapiens (human)   TNKS Order cDNA clone, Links
Tankyrase, TRF1-interacting ankyrin-related ADP-ribose polymerase (TNKS)

Human protein-coding gene TNKS. Represented by 388 ESTs from 186 cDNA libraries. Corresponds to reference sequence NM_003747.2. [UniGene 198563 - Hs.370267]

SELECTED PROTEIN SIMILARITIES
Comparison of cluster transcripts with RefSeq proteins. The alignments can suggest function of the cluster.
Best Hits and Hits from model organismsSpeciesId(%)Len(aa)
NP_003738.2 TNKS gene product H. sapiens 100.0 1326
XP_004021798.1 PREDICTED: tankyrase-1 isoform 1 O. aries 99.8 1089
XP_003902487.1 PREDICTED: tankyrase-1 isoform 1 P. anubis 99.8 1326
XP_001090358.1 PREDICTED: tankyrase-1 M. mulatta 99.7 1326
XP_001137443.1 PREDICTED: tankyrase-1 isoform 2 P. troglodytes 99.7 1326
NP_780300.2 Tnks gene product M. musculus 98.1 1319
XP_687410.2 PREDICTED: tankyrase-1 D. rerio 93.0 1238
NP_001088420.1 tankyrase, TRF1-interacting ankyrin-related ADP-ribose polymerase 2 X. laevis 92.3 1300
NP_651410.1 tankyrase, isoform A D. melanogaster 68.9 1163
Other hits (2 of 31) [Show all]SpeciesId(%)Len(aa)
XP_001496028.2 PREDICTED: LOW QUALITY PROTEIN: tankyrase-1-like E. caballus 99.2 1326
XP_849388.1 PREDICTED: tankyrase-1 isoform 3 C. lupus familiaris 99.1 1326

GENE EXPRESSION
Tissues and development stages from this gene's sequences survey gene expression. Links to other NCBI expression resources.
EST Profile: Approximate expression patterns inferred from EST sources.
[Show more entries with profiles like this]
GEO Profiles: Experimental gene expression data (Gene Expression Omnibus).
cDNA Sources: brain; testis; mixed; uncharacterized tissue; embryonic tissue; prostate; placenta; skin; vascular; eye; pancreas; kidney; mouth; ear; lung; uterus; intestine; esophagus; trachea; thymus; lymph; bladder; cervix; blood; ascites; muscle; adrenal gland; bone; ganglia; nerve; lymph node; mammary gland; bone marrow; liver; pituitary gland; adipose tissue; spleen; connective tissue; ovary; heart; spinal cord; parathyroid
MAPPING POSITION
Genomic location specified by transcript mapping, radiation hybrid mapping, genetic mapping or cytogenetic mapping.
Chromosome: 8
Map position: 8p23.1
UniSTS entry: Chr 8 A005X23
UniSTS entry: Chr 8 G20573
UniSTS entry: Chr 8 HSC2QE062 [Map Viewer]
UniSTS entry: Chr 8 SHGC-24414 [Map Viewer]
UniSTS entry: Chr 8 SHGC-132382
UniSTS entry: Chr 8 RH103385
UniSTS entry: Chr 8 RH11883
UniSTS entry: Chr 8 RH18302 [Map Viewer]
UniSTS entry: Chr 8 RH104269
UniSTS entry: Chr 1 PMC156606P2
SEQUENCES
Sequences representing this gene; mRNAs, ESTs, and gene predictions supported by transcribed sequences.

mRNA sequences (11)

AF070613.1 Homo sapiens clone 24585 mRNA sequence A
AF082556.1 Homo sapiens TRF1-interacting ankyrin-related ADP-ribose polymerase mRNA, complete cds P
AF082557.1 Homo sapiens TRF1-interacting ankyrin-related ADP-ribose polymerase mRNA, partial cds PA
AF082558.1 Homo sapiens truncated TRF1-interacting ankyrin-related ADP-ribose polymerase TT7 mRNA, alternatively spliced, partial cds
AF082559.1 Homo sapiens truncated TRF1-interacting ankyrin-related ADP-ribose polymerase TT9 mRNA, alternatively spliced, partial cds
NM_003747.2 Homo sapiens tankyrase, TRF1-interacting ankyrin-related ADP-ribose polymerase (TNKS), mRNA P
AB209339.1 Homo sapiens mRNA for tankyrase, TRF1-interacting ankyrin-related ADP-ribose polymerase variant protein P
BC098394.1 Homo sapiens tankyrase, TRF1-interacting ankyrin-related ADP-ribose polymerase, mRNA (cDNA clone MGC:104648 IMAGE:4374347), complete cds PA
AK301798.1 Homo sapiens cDNA FLJ61441 complete cds, highly similar to Tankyrase-1 (EC 2.4.2.30) P
AK302534.1 Homo sapiens cDNA FLJ50918 complete cds, highly similar to Tankyrase-1 (EC 2.4.2.30) P
AK302031.1 Homo sapiens cDNA FLJ58090 complete cds, highly similar to Tankyrase-1 (EC 2.4.2.30) PA

EST sequences (10 of 388) [Show all sequences]

AA977611.1 Clone IMAGE:1561188 mixed 3' read P
AA902808.1 Clone IMAGE:1519151 uncharacterized tissue 3' read A
AI002049.1 Clone IMAGE:1637809 mammary gland 3' read
AI017504.1 Clone IMAGE:1627679 mixed 3' read
AI040551.1 Clone IMAGE:1657177 mixed 3' read
CB054908.1 Clone IMAGE:3291875 brain 5' read
CB054909.1 Clone IMAGE:3291877 brain 3' read A
AI147680.1 Clone IMAGE:1697523 uterus 3' read A
R24339.1 Clone IMAGE:34198 brain 5' read
BX116469.1 Clone IMAGp998P01593_;_IMAGE:270192 skin


Key to Symbols

P Has similarity to known Proteins (after translation)
A Contains a poly-Adenylation signal
S Sequence is a Suboptimal member of this cluster
M Clone is putatively CDS-complete by MGC criteria

 
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