> Amyloid beta (A4) precursor-like protein 2 (APLP2)
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UGID:198549     UniGene Hs.370247     Homo sapiens (human)   APLP2 Order cDNA clone, Links
Amyloid beta (A4) precursor-like protein 2 (APLP2)

Human protein-coding gene APLP2. Represented by 15375 ESTs from 733 cDNA libraries. Corresponds to 7 reference sequences (different isoforms). [UniGene 198549 - Hs.370247]

SELECTED PROTEIN SIMILARITIES
Comparison of cluster transcripts with RefSeq proteins. The alignments can suggest function of the cluster.
Best Hits and Hits from model organismsSpeciesId(%)Len(aa)
NP_001230228.1 APLP2 gene product H. sapiens 100.0 760
XP_001154299.1 PREDICTED: amyloid beta (A4) precursor-like protein 2 isoform 10 P. troglodytes 99.9 758
XP_001112057.2 PREDICTED: amyloid beta (A4) precursor-like protein 2 M. mulatta 99.6 697
NP_001095925.1 Aplp2 gene product M. musculus 97.7 750
NP_001238753.1 amyloid beta (A4) precursor-like protein 2 isoform 2 precursor X. laevis 87.6 748
NP_001116484.1 aplp2 gene product D. rerio 85.2 763
Other hits (2 of 19) [Show all]SpeciesId(%)Len(aa)
XP_003911016.1 PREDICTED: amyloid-like protein 2 isoform 3 P. anubis 99.5 762
XP_536530.2 PREDICTED: amyloid beta (A4) precursor-like protein 2 isoform 1 C. lupus familiaris 98.2 762

GENE EXPRESSION
Tissues and development stages from this gene's sequences survey gene expression. Links to other NCBI expression resources.
EST Profile: Approximate expression patterns inferred from EST sources.
[Show more entries with profiles like this]
GEO Profiles: Experimental gene expression data (Gene Expression Omnibus).
cDNA Sources: brain; testis; trachea; uterus; kidney; placenta; mouth; connective tissue; vascular; skin; mammary gland; thymus; lung; blood; liver; uncharacterized tissue; embryonic tissue; intestine; mixed; pancreas; prostate; eye; heart; esophagus; stomach; thyroid; ovary; bladder; parathyroid; ascites; spleen; bone marrow; pineal gland; adrenal gland; lymph node; bone; muscle; umbilical cord; pharynx; cervix; larynx; adipose tissue; ganglia; nerve; amniotic fluid; ear; lymph; pituitary gland; epididymis
MAPPING POSITION
Genomic location specified by transcript mapping, radiation hybrid mapping, genetic mapping or cytogenetic mapping.
Chromosome: 11
Map position: 11q24
UniSTS entry: Chr 11 RH11795 [Map Viewer]
UniSTS entry: Chr 11 SGC44685 [Map Viewer]
UniSTS entry: Chr 11 SHGC-30035 [Map Viewer]
UniSTS entry: Chr 11 RH27778
UniSTS entry: Chr 11 D11S3981 [Map Viewer]
UniSTS entry: Chr 11 D11S1945E
UniSTS entry: Chr 1 D8S2278
UniSTS entry: Chr 8 RH27907
SEQUENCES
Sequences representing this gene; mRNAs, ESTs, and gene predictions supported by transcribed sequences.

mRNA sequences (26)

L23113.1 Human binding protein mRNA, 3'end P
L23114.1 Human binding protein mRNA, 3'end P
AK128162.1 Homo sapiens cDNA FLJ46285 fis, clone TESTI4032128, highly similar to Amyloid-like protein 2 precursor (Amyloid protein homolog) (APPH) (CDEI box-binding protein)(CDEBP) P
NM_001642.2 Homo sapiens amyloid beta (A4) precursor-like protein 2 (APLP2), transcript variant 1, mRNA PA
AF168956.1 Homo sapiens amyloid precursor protein homolog HSD-2 mRNA, complete cds P
L27631.1 Human amyloid precursor-like protein 2 (APLP2) mRNA, complete cds P
BC000373.2 Homo sapiens amyloid beta (A4) precursor-like protein 2, mRNA (cDNA clone MGC:8371 IMAGE:2820109), complete cds PA
AK225283.1 Homo sapiens mRNA for Binding protein variant, clone: HEP00895 PA
BC004371.1 Homo sapiens amyloid beta (A4) precursor-like protein 2, mRNA (cDNA clone MGC:10449 IMAGE:3640033), complete cds PA
Z22572.1 H.sapiens CDEI binding protein mRNA PA
AK056883.1 Homo sapiens cDNA FLJ32321 fis, clone PROST2003563, highly similar to AMYLOID-LIKE PROTEIN 2 PRECURSOR P
AK308932.1 Homo sapiens cDNA, FLJ98973 P
AK308248.1 Homo sapiens cDNA, FLJ98196 PA
AK300378.1 Homo sapiens cDNA FLJ55927 complete cds, highly similar to Amyloid-like protein 2 precursor (CDEIbox-binding protein) (CDEBP) P
AK304736.1 Homo sapiens cDNA FLJ56216 complete cds, highly similar to Amyloid-like protein 2 precursor (CDEIbox-binding protein) (CDEBP) P
AK296765.1 Homo sapiens cDNA FLJ55088 complete cds, highly similar to Amyloid-like protein 2 precursor (Amyloidprotein homolog) (APPH) (CDEI box-binding protein)(CDEBP) P
AF086183.1 Homo sapiens full length insert cDNA clone ZB97H06 A
NM_001142278.1 Homo sapiens amyloid beta (A4) precursor-like protein 2 (APLP2), transcript variant 4, mRNA PA
NM_001142277.1 Homo sapiens amyloid beta (A4) precursor-like protein 2 (APLP2), transcript variant 3, mRNA PA
NM_001142276.1 Homo sapiens amyloid beta (A4) precursor-like protein 2 (APLP2), transcript variant 2, mRNA PA
L19597.1 Human binding protein mRNA, partial cds P
S60099.1 APPH=amyloid precursor protein homolog [human, placenta, mRNA, 3727 nt] P
NM_001243299.1 Homo sapiens amyloid beta (A4) precursor-like protein 2 (APLP2), transcript variant 7, mRNA PA
NR_024515.1 Homo sapiens amyloid beta (A4) precursor-like protein 2 (APLP2), transcript variant 5, non-coding RNA PA
NR_024516.1 Homo sapiens amyloid beta (A4) precursor-like protein 2 (APLP2), transcript variant 6, non-coding RNA PA
L09209.1 Homo sapiens amyloid protein homologue mRNA, complete cds P

EST sequences (10 of 15375) [Show all sequences]

AA866146.1 Clone IMAGE:1469345 uncharacterized tissue 3' read
AA962080.1 Clone IMAGE:1599505 uncharacterized tissue 3' read
AA962305.1 Clone IMAGE:1569889 lung 3' read P
AA971686.1 Clone IMAGE:1583641 mixed 3' read
AA972570.1 Clone IMAGE:1584739 lung 3' read A
AA973350.1 Clone IMAGE:1568906 lung 3' read
AA973747.1 Clone IMAGE:1586039 uncharacterized tissue 3' read
R15449.1 Clone IMAGE:53084 brain 3' read
R15450.1 Clone IMAGE:53084 brain 5' read P
AA975058.1 Clone IMAGE:1555588 kidney 3' read


Key to Symbols

P Has similarity to known Proteins (after translation)
A Contains a poly-Adenylation signal
S Sequence is a Suboptimal member of this cluster
M Clone is putatively CDS-complete by MGC criteria

 
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