> RAP1B, member of RAS oncogene family (RAP1B)
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UGID:198360     UniGene Hs.369920     Homo sapiens (human)   RAP1B Order cDNA clone, Links
RAP1B, member of RAS oncogene family (RAP1B)

Human protein-coding gene RAP1B. Represented by 1554 ESTs from 385 cDNA libraries. Corresponds to 6 reference sequences (different isoforms). [UniGene 198360 - Hs.369920]

SELECTED PROTEIN SIMILARITIES
Comparison of cluster transcripts with RefSeq proteins. The alignments can suggest function of the cluster.
Best Hits and Hits from model organismsSpeciesId(%)Len(aa)
NP_077777.1 Rap1b gene product M. musculus 100.0 183
NP_599173.2 Rap1b gene product R. norvegicus 100.0 183
XP_001364299.1 PREDICTED: ras-related protein Rap-1b-like M. domestica 100.0 183
XP_003224659.1 PREDICTED: ras-related protein Rap-1b-like A. carolinensis 100.0 183
XP_002189752.1 PREDICTED: ras-related protein Rap-1b T. guttata 100.0 183
NP_001080191.1 ras-related protein Rap-1b precursor X. laevis 100.0 183
NP_001008195.1 rap1b gene product X. tropicalis 100.0 183
NP_001007853.1 RAP1B gene product G. gallus 100.0 183
XP_003202098.1 PREDICTED: ras-related protein Rap-1b-like M. gallopavo 100.0 183
XP_001511363.1 PREDICTED: ras-related protein Rap-1b-like isoform 1 O. anatinus 100.0 183
XP_001117189.1 PREDICTED: ras-related protein Rap-1b M. mulatta 100.0 183
XP_003906797.1 PREDICTED: ras-related protein Rap-1b isoform 1 P. anubis 100.0 183
NP_001092015.1 RAP1B gene product P. troglodytes 100.0 183
NP_001010942.1 RAP1B gene product H. sapiens 100.0 183
XP_851250.1 PREDICTED: ras-related protein Rap-1b isoform 2 C. lupus familiaris 100.0 183
XP_003481702.1 PREDICTED: ras-related protein Rap-1b S. scrofa 100.0 183
NP_787018.1 RAP1B gene product B. taurus 100.0 183
XP_004006532.1 PREDICTED: ras-related protein Rap-1b isoform 1 O. aries 100.0 183
XP_002711365.1 PREDICTED: RAP1B, member of RAS oncogene family O. cuniculus 100.0 183
NP_955827.1 rap1b gene product D. rerio 98.9 183
NP_501549.1 Protein RAP-1 C. elegans 94.7 187
NP_476857.1 roughened, isoform A D. melanogaster 94.6 183
NP_011668.3 Rsr1p S. cerevisiae 63.2 209
XP_961863.2 GTPase NRas precursor N. crassa 58.8 177
Other hits (2 of 36) [Show all]SpeciesId(%)Len(aa)
NP_001187514.1 ras-related protein Rap-1b I. punctatus 98.9 184
NP_001158692.1 ras-related protein Rap-1b O. mykiss 98.4 184

GENE EXPRESSION
Tissues and development stages from this gene's sequences survey gene expression. Links to other NCBI expression resources.
EST Profile: Approximate expression patterns inferred from EST sources.
[Show more entries with profiles like this]
GEO Profiles: Experimental gene expression data (Gene Expression Omnibus).
cDNA Sources: brain; uncharacterized tissue; testis; lung; placenta; blood; uterus; connective tissue; thymus; intestine; embryonic tissue; kidney; vascular; spleen; skin; liver; heart; esophagus; cervix; adrenal gland; prostate; bladder; stomach; pancreas; mammary gland; eye; mixed; lymph node; amniotic fluid; bone marrow; ovary; bone; mouth; trachea; pituitary gland; muscle; tonsil; umbilical cord; ear; ascites; parathyroid; thyroid; lymph; adipose tissue; larynx; nerve; ganglia; salivary gland
MAPPING POSITION
Genomic location specified by transcript mapping, radiation hybrid mapping, genetic mapping or cytogenetic mapping.
Chromosome: 12
Map position: 12q14
UniSTS entry: Chr 9 MARC_2660-2661:991933047:1
UniSTS entry: Chr 9 GDB:384854
UniSTS entry: Chr 6 SHGC-12704 [Map Viewer]
UniSTS entry: Chr 12 D12S1240E
UniSTS entry: Chr 1 D11S2921
UniSTS entry: Chr 12 D12S1975
SEQUENCES
Sequences representing this gene; mRNAs, ESTs, and gene predictions supported by transcribed sequences.

mRNA sequences (23)

AL080212.1 Homo sapiens mRNA; cDNA DKFZp586H0723 (from clone DKFZp586H0723) PA
X08004.1 Human mRNA for Rap1B protein P
CR407689.1 Homo sapiens full open reading frame cDNA clone RZPDo834E013D for gene RAP1B, RAP1B, member of RAS oncogene family complete cds, without stopcodon P
BC078173.1 Homo sapiens RAP1B, member of RAS oncogene family, mRNA (cDNA clone MGC:87966 IMAGE:6015817), complete cds PA
NM_015646.5 Homo sapiens RAP1B, member of RAS oncogene family (RAP1B), transcript variant 1, mRNA PA
BT020093.1 Homo sapiens RAP1B, member of RAS oncogene family mRNA, complete cds P
NM_001010942.2 Homo sapiens RAP1B, member of RAS oncogene family (RAP1B), transcript variant 2, mRNA PA
BC095467.1 Homo sapiens RAP1B, member of RAS oncogene family, mRNA (cDNA clone MGC:111368 IMAGE:30523718), complete cds PA
BC000176.3 Homo sapiens RAP1B, member of RAS oncogene family, mRNA (cDNA clone MGC:5214 IMAGE:2900837), complete cds PA
AJ420497.1 Homo sapiens mRNA full length insert cDNA clone EUROIMAGE 1916608 PA
AK312371.1 Homo sapiens cDNA, FLJ92694, Homo sapiens RAP1B, member of RAS oncogene family (RAP1B), mRNA P
AF493913.1 Homo sapiens Ras family small GTP binding protein RAP1B (RAL1B) mRNA, complete cds P
AB062128.1 Homo sapiens OK/SW-cl.11 mRNA for RAS oncogene family member RAP1B, complete cds PA
AK301428.1 Homo sapiens cDNA FLJ50714 complete cds, moderately similar to Ras-related protein Rap-1b precursor P
AK301401.1 Homo sapiens cDNA FLJ50711 complete cds, moderately similar to Ras-related protein Rap-1b precursor P
AK298818.1 Homo sapiens cDNA FLJ51696 complete cds, highly similar to Ras-related protein Rap-1b precursor P
AF279894.1 Homo sapiens PNAS-140 mRNA, partial cds P
AK316447.1 Homo sapiens cDNA, FLJ79346 complete cds, highly similar to Ras-related protein Rap-1b precursor P
AK316543.1 Homo sapiens cDNA, FLJ79442 complete cds, highly similar to Ras-related protein Rap-1b precursor P
NM_001251921.1 Homo sapiens RAP1B, member of RAS oncogene family (RAP1B), transcript variant 5, mRNA PA
NM_001251918.1 Homo sapiens RAP1B, member of RAS oncogene family (RAP1B), transcript variant 4, mRNA PA
NM_001251922.1 Homo sapiens RAP1B, member of RAS oncogene family (RAP1B), transcript variant 6, mRNA PA
NM_001251917.1 Homo sapiens RAP1B, member of RAS oncogene family (RAP1B), transcript variant 3, mRNA PA

EST sequences (10 of 1554) [Show all sequences]

AA987662.1 Clone IMAGE:1604360 lung 3' read
AI003944.1 Clone IMAGE:1624393 embryonic tissue 3' read A
AI004581.1 Clone IMAGE:1625272 embryonic tissue 3' read A
AI024706.1 Clone IMAGE:1642524 testis 3' read A
AI026112.1 Clone IMAGE:1645794 parathyroid 3' read
AI052012.1 Clone IMAGE:1667251 parathyroid 3' read A
AI056695.1 Clone IMAGE:1676503 embryonic tissue 3' read A
AI127969.1 Clone IMAGE:1711760 uterus 3' read A
AI138890.1 Clone IMAGE:1737601 testis 3' read A
CB068617.1 Clone IMAGE:6554042 pancreas 3' read A


Key to Symbols

P Has similarity to known Proteins (after translation)
A Contains a poly-Adenylation signal
S Sequence is a Suboptimal member of this cluster
M Clone is putatively CDS-complete by MGC criteria

 
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