> RAB2A, member RAS oncogene family (RAB2A)
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UGID:197846     UniGene Hs.369017     Homo sapiens (human)   RAB2A
RAB2A, member RAS oncogene family (RAB2A)

Human protein-coding gene RAB2A. Represented by 1353 ESTs from 396 cDNA libraries. Corresponds to 2 reference sequences (different isoforms). [UniGene 197846 - Hs.369017]

SELECTED PROTEIN SIMILARITIES
Comparison of cluster transcripts with RefSeq proteins. The alignments can suggest function of the cluster.
Best Hits and Hits from model organismsSpeciesId(%)Len(aa)
NP_067493.1 Rab2a gene product M. musculus 100.0 211
NP_113906.1 Rab2a gene product R. norvegicus 100.0 211
XP_002198446.1 PREDICTED: ras-related protein Rab-2A isoform 1 T. guttata 100.0 211
NP_958862.1 rab2a gene product D. rerio 100.0 211
NP_001133505.1 ras-related protein Rab-2A S. salar 100.0 211
NP_990559.1 RAB2A gene product G. gallus 100.0 211
XP_001513461.2 PREDICTED: ras-related protein Rab-2A-like O. anatinus 100.0 211
XP_001089894.1 PREDICTED: ras-related protein Rab-2A-like isoform 3 M. mulatta 100.0 211
XP_003902845.1 PREDICTED: ras-related protein Rab-2A isoform 1 P. anubis 100.0 211
NP_001233386.1 RAB2A gene product P. troglodytes 100.0 211
NP_002856.1 RAB2A gene product H. sapiens 100.0 211
NP_001003318.1 RAB2A gene product C. lupus familiaris 100.0 211
XP_001926739.2 PREDICTED: ras-related protein Rab-2A S. scrofa 100.0 211
NP_001095172.1 RAB2A gene product O. cuniculus 100.0 211
XP_003219638.1 PREDICTED: ras-related protein Rab-2A-like A. carolinensis 100.0 206
XP_001379431.2 PREDICTED: ras-related protein Rab-2A-like, partial M. domestica 100.0 202
XP_002612378.1 hypothetical protein BRAFLDRAFT_58617 B. floridae 99.5 213
XP_003978510.1 PREDICTED: ras-related protein Rab-2A-like T. rubripes 99.5 211
XP_004079196.1 PREDICTED: ras-related protein Rab-2A-like O. latipes 99.5 211
XP_003453208.1 PREDICTED: ras-related protein Rab-2A-like O. niloticus 99.5 211
XP_002936157.1 PREDICTED: ras-related protein Rab-2A X. tropicalis 99.5 210
XP_004012017.1 PREDICTED: ras-related protein Rab-2A O. aries 99.5 209
NP_001090137.1 RAB2A, member RAS oncogene family X. laevis 97.8 227
NP_477090.1 Rab2, isoform A D. melanogaster 97.2 212
NP_491233.1 Protein UNC-108 C. elegans 96.7 213
XP_001695070.1 small rab-related GTPase C. reinhardtii 93.0 212
NP_193450.1 RAB GTPase homolog B1C A. thaliana 91.9 210
XP_956972.2 GTP-binding protein ypt3 N. crassa 56.9 208
NP_010948.1 Ypt31p S. cerevisiae 52.1 216
Other hits (2 of 49) [Show all]SpeciesId(%)Len(aa)
XP_001496741.2 PREDICTED: ras-related protein Rab-2A-like E. caballus 99.1 214
XP_002155452.1 PREDICTED: ras-related protein Rab-2-like H. magnipapillata 98.6 211

GENE EXPRESSION
Tissues and development stages from this gene's sequences survey gene expression. Links to other NCBI expression resources.
EST Profile: Approximate expression patterns inferred from EST sources.
[Show more entries with profiles like this]
GEO Profiles: Experimental gene expression data (Gene Expression Omnibus).
cDNA Sources: brain; lung; mixed; testis; placenta; skin; uterus; pancreas; embryonic tissue; prostate; kidney; connective tissue; uncharacterized tissue; intestine; heart; mammary gland; blood; stomach; eye; tonsil; liver; lymph node; bladder; muscle; umbilical cord; trachea; vascular; spleen; pharynx; ear; mouth; ascites; thyroid; ovary; parathyroid; adrenal gland; pineal gland; bone; thymus; pituitary gland; esophagus; cervix; nerve; lymph; bone marrow
MAPPING POSITION
Genomic location specified by transcript mapping, radiation hybrid mapping, genetic mapping or cytogenetic mapping.
Chromosome: 8
Map position: 8q12.1
UniSTS entry: Chr 8 STS-R00195
UniSTS entry: Chr 8 RH70011
UniSTS entry: Chr 8 RH92689
UniSTS entry: Chr 8 D8S1899 [Map Viewer]
UniSTS entry: Chr 8 D8S1929 [Map Viewer]
UniSTS entry: Chr 8 D8S1613 [Map Viewer]
UniSTS entry: Chr 8 D8S1405E
UniSTS entry: Chr 8 D8S1394E
UniSTS entry: Chr 8 RAB2_2543
SEQUENCES
Sequences representing this gene; mRNAs, ESTs, and gene predictions supported by transcribed sequences.

mRNA sequences (13)

AF070629.1 Homo sapiens clone 24484 RAB2 mRNA, partial cds PA
NM_002865.2 Homo sapiens RAB2A, member RAS oncogene family (RAB2A), transcript variant 1, mRNA PA
AL137321.1 Homo sapiens mRNA; cDNA DKFZp434P231 (from clone DKFZp434P231) A
BT019695.1 Homo sapiens RAB2, member RAS oncogene family mRNA, complete cds P
M28213.1 Homo sapiens GTP-binding protein (RAB2) mRNA, complete cds P
BC008929.2 Homo sapiens RAB2A, member RAS oncogene family, mRNA (cDNA clone MGC:1656 IMAGE:2966694), complete cds PA
AK312344.1 Homo sapiens cDNA, FLJ92663, Homo sapiens RAB2, member RAS oncogene family (RAB2), mRNA P
AF498930.1 Homo sapiens small GTP binding protein RAB2A (RAB2A) mRNA, complete cds P
AK297576.1 Homo sapiens cDNA FLJ51998 complete cds, highly similar to Ras-related protein Rab-2A P
AY034106.1 Homo sapiens bladder cancer-related protein (LHX) gene, partial 3'UTR sequence A
S48723.1 rab2=low molecular weight GTP-binding protein {3' region} [human, mRNA Partial, 103 nt]
X12953.1 Human rab2 mRNA, YPT1-related and member of ras family P
NM_001242644.1 Homo sapiens RAB2A, member RAS oncogene family (RAB2A), transcript variant 2, mRNA PA

EST sequences (10 of 1353) [Show all sequences]

AA954521.1 Clone IMAGE:1555051 kidney 3' read PA
AA961704.1 Clone IMAGE:1598330 uncharacterized tissue 3' read P
AA975190.1 Clone IMAGE:1555395 kidney 3' read
AA987649.1 Clone IMAGE:1604331 lung 3' read A
AA988611.1 Clone IMAGE:1604691 lung 3' read P
AA988644.1 Clone IMAGE:1604750 lung 3' read PA
AA992899.1 Clone IMAGE:1624218 embryonic tissue 3' read P
AA994557.1 Clone IMAGE:1621297 testis 3' read PA
AI001068.1 Clone IMAGE:1610310 mammary gland 3' read PA
AA910717.1 Clone IMAGE:1521187 lung 3' read P


Key to Symbols

P Has similarity to known Proteins (after translation)
A Contains a poly-Adenylation signal
S Sequence is a Suboptimal member of this cluster
M Clone is putatively CDS-complete by MGC criteria

 
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