> Sortilin-related receptor, L(DLR class) A repeats containing (SORL1)
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UGID:197625     UniGene Hs.368592     Homo sapiens (human)   SORL1 Order cDNA clone, Links
Sortilin-related receptor, L(DLR class) A repeats containing (SORL1)

Human protein-coding gene SORL1. Represented by 778 ESTs from 243 cDNA libraries. Corresponds to reference sequence NM_003105.5. [UniGene 197625 - Hs.368592]

SELECTED PROTEIN SIMILARITIES
Comparison of cluster transcripts with RefSeq proteins. The alignments can suggest function of the cluster.
Best Hits and Hits from model organismsSpeciesId(%)Len(aa)
NP_003096.1 SORL1 gene product H. sapiens 100.0 2213
XP_003313440.1 PREDICTED: LOW QUALITY PROTEIN: sortilin-related receptor P. troglodytes 99.6 2211
NP_035566.2 Sorl1 gene product M. musculus 95.5 2214
XP_003200086.1 PREDICTED: sortilin-related receptor D. rerio 70.3 2118
NP_001097931.2 lipophorin receptor 1, isoform I D. melanogaster 47.9 240
NP_001084168.1 very low-density lipoprotein receptor precursor X. laevis 46.2 173
NP_492127.1 Protein LRP-1 C. elegans 45.4 196
Other hits (2 of 35) [Show all]SpeciesId(%)Len(aa)
XP_003910898.1 PREDICTED: sortilin-related receptor P. anubis 99.4 2213
XP_001102178.2 PREDICTED: sortilin-related receptor-like M. mulatta 98.9 2077

GENE EXPRESSION
Tissues and development stages from this gene's sequences survey gene expression. Links to other NCBI expression resources.
EST Profile: Approximate expression patterns inferred from EST sources.
[Show more entries with profiles like this]
GEO Profiles: Experimental gene expression data (Gene Expression Omnibus).
cDNA Sources: mixed; brain; lymph node; blood; liver; testis; intestine; uncharacterized tissue; bone marrow; kidney; esophagus; pancreas; uterus; eye; lung; thyroid; adipose tissue; mammary gland; ovary; thymus; mouth; prostate; placenta; vascular; trachea; bone; bladder; connective tissue; ear; spleen; embryonic tissue; pituitary gland; pharynx; lymph; skin; muscle; stomach; nerve; ganglia; heart; parathyroid
MAPPING POSITION
Genomic location specified by transcript mapping, radiation hybrid mapping, genetic mapping or cytogenetic mapping.
Chromosome: 11
Map position: 11q23.2-q24.2
UniSTS entry: Chr 11 RH12473
UniSTS entry: Chr 11 G19692
UniSTS entry: Chr 11 A001V33
UniSTS entry: Chr 11 T15980
UniSTS entry: Chr 11 D11S2303E
UniSTS entry: Chr 11 MARC_13961-13962:1007650350:1
UniSTS entry: Chr 11 RH12302
UniSTS entry: Chr 11 RH45842
UniSTS entry: Chr 11 SHGC-53425
UniSTS entry: Chr 11 RH11765
SEQUENCES
Sequences representing this gene; mRNAs, ESTs, and gene predictions supported by transcribed sequences.

mRNA sequences (14)

NM_003105.5 Homo sapiens sortilin-related receptor, L(DLR class) A repeats containing (SORL1), mRNA PA
AK025583.1 Homo sapiens cDNA: FLJ21930 fis, clone HEP04301, highly similar to HSU90916 Human clone 23815 mRNA sequence A
AK309523.1 Homo sapiens cDNA, FLJ99564 P
BC137171.1 Homo sapiens sortilin-related receptor, L(DLR class) A repeats-containing, mRNA (cDNA clone MGC:168791 IMAGE:9021168), complete cds P
AK096577.1 Homo sapiens cDNA FLJ39258 fis, clone OCBBF2009242 A
AK294404.1 Homo sapiens cDNA FLJ53877 complete cds, highly similar to Sortilin-related receptor precursor P
AK295878.1 Homo sapiens cDNA FLJ50970 complete cds, highly similar to Sortilin-related receptor precursor P
AK302589.1 Homo sapiens cDNA FLJ51150 complete cds, highly similar to Sortilin-related receptor precursor P
AK295090.1 Homo sapiens cDNA FLJ50960 complete cds, highly similar to Sortilin-related receptor precursor P
Y08110.1 H.sapiens mRNA for mosaic protein LR11 P
AK316340.1 Homo sapiens cDNA, FLJ79239 complete cds, highly similar to Sortilin-related receptor precursor PA
BC032903.1 Homo sapiens cDNA clone IMAGE:5262040
U90916.1 Human clone 23815 mRNA sequence A
BC040643.1 Homo sapiens chromosome 11 open reading frame 32, mRNA (cDNA clone IMAGE:4792314) A

EST sequences (10 of 778) [Show all sequences]

AA972515.1 Clone IMAGE:1575753 intestine 3' read P
AA975525.1 Clone IMAGE:1558223 lung 3' read A
AA977151.1 Clone IMAGE:1587334 uncharacterized tissue 3' read P
AA984813.1 Clone IMAGE:1630671 brain 3' read P
AA992019.1 Clone IMAGE:1618843 testis 3' read
AI002816.1 Clone IMAGE:1684154 brain 3' read
AI003010.1 Clone IMAGE:1683905 brain 3' read
AI049681.1 Clone IMAGE:1700445 kidney 3' read P
R19934.1 Clone IMAGE:34136 brain 5' read
AI089413.1 Clone IMAGE:1685656 brain 3' read P


Key to Symbols

P Has similarity to known Proteins (after translation)
A Contains a poly-Adenylation signal
S Sequence is a Suboptimal member of this cluster
M Clone is putatively CDS-complete by MGC criteria

 
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