ATP-binding cassette, sub-family C (CFTR/MRP), member 2 (ABCC2)

Restricted Expression:

fetus [show more like this]

EST Profile:

Approximate expression patterns inferred from EST sources.
[Show more entries with profiles like this]

GEO Profiles:

Experimental gene expression data (Gene Expression Omnibus).

cDNA Sources:

mixed; liver; uncharacterized tissue; testis; kidney; lung; mammary gland; brain; connective tissue; stomach; intestine; ovary; bone; placenta; cervix; uterus

NCBI

UniGene
Homepage
FAQs
Help
Query Tips
Build Info
Library Browser
DDD
Download UniGene

Related Databases
Gene
HomoloGene
EST
SRA

NIH cDNA Projects
MGC | ZGC | XGC
Finding cDNAs

UGID:197407 UniGene Hs.368243 Homo sapiens (human) ABCC2

Order cDNA clone, Links

ATP-binding cassette, sub-family C (CFTR/MRP), member 2 (ABCC2)

Human protein-coding gene ABCC2. Represented by 100 ESTs from 38 cDNA libraries. EST representation biased toward fetus. Corresponds to reference sequence NM_000392.3. [UniGene 197407 - Hs.368243]

SELECTED PROTEIN SIMILARITIES

Comparison of cluster transcripts with RefSeq proteins. The alignments can suggest function of the cluster.

Best Hits and Hits from model organisms		Species	Id(%)	Len(aa)
NP_000383.1 Conserved domains (CDD) Gene summary Protein sequence Protein/EST matches (ProtEST) Protein/protein matches (BLink)	ABCC2 gene product	H. sapiens	100.0	1544
NP_038834.2 Conserved domains (CDD) Gene summary Protein sequence Protein/EST matches (ProtEST) Protein/protein matches (BLink)	Abcc2 gene product	M. musculus	81.5	1542
NP_001024719.1 Conserved domains (CDD) Gene summary Protein sequence Protein/EST matches (ProtEST) Protein/protein matches (BLink)	Protein MRP-1, isoform d	C. elegans	62.4	327
NP_956883.1 Conserved domains (CDD) Gene summary Protein sequence Protein/EST matches (ProtEST) Protein/protein matches (BLink)	canalicular multispecific organic anion transporter 1	D. rerio	62.4	1551
NP_010419.3 Conserved domains (CDD) Gene summary Protein sequence Protein/EST matches (ProtEST) Protein/protein matches (BLink)	ATP-binding cassette glutathione S-conjugate transporter YCF1	S. cerevisiae	57.8	492
XP_958146.1 Conserved domains (CDD) Gene summary Protein sequence Protein/EST matches (ProtEST) Protein/protein matches (BLink)	hypothetical protein NCU09012	N. crassa	55.0	489
NP_191829.1 Conserved domains (CDD) Gene summary Protein sequence Protein/EST matches (ProtEST) Protein/protein matches (BLink)	ABC transporter C family member 14	A. thaliana	53.8	392
NP_995704.1 Conserved domains (CDD) Gene summary Protein sequence Protein/EST matches (ProtEST) Protein/protein matches (BLink)	Multidrug-Resistance like protein 1, isoform M	D. melanogaster	52.6	1539
XP_001696082.1 Conserved domains (CDD) Gene summary Protein sequence Protein/EST matches (ProtEST) Protein/protein matches (BLink)	hypothetical protein CHLREDRAFT_119551	C. reinhardtii	48.4	282
Other hits (2 of 63) [Show all]		Species	Id(%)	Len(aa)
NP_001028019.1 Conserved domains (CDD) Gene summary Protein sequence Protein/EST matches (ProtEST) Protein/protein matches (BLink)	ABCC2 gene product	M. mulatta	96.6	1542
XP_003904164.1 Conserved domains (CDD) Gene summary Protein sequence Protein/EST matches (ProtEST) Protein/protein matches (BLink)	PREDICTED: canalicular multispecific organic anion transporter 1	P. anubis	96.5	1533

GENE EXPRESSION

Tissues and development stages from this gene's sequences survey gene expression. Links to other NCBI expression resources.

MAPPING POSITION

Genomic location specified by transcript mapping, radiation hybrid mapping, genetic mapping or cytogenetic mapping.

Chromosome:	10
Map position:	10q24
UniSTS entry:	Chr 10	D10S2172	[Map Viewer]
UniSTS entry:	Chr 10	RH17884	[Map Viewer]
UniSTS entry:	Chr 10	ABCC2
UniSTS entry:	Chr 3	SHGC-77535	[Map Viewer]
UniSTS entry:	Chr 10	D10S2421

SEQUENCES

Sequences representing this gene; mRNAs, ESTs, and gene predictions supported by transcribed sequences.

mRNA sequences (5)

NM_000392.3	Homo sapiens ATP-binding cassette, sub-family C (CFTR/MRP), member 2 (ABCC2), mRNA	P
X96395.2	H.sapiens mRNA for canalicular multidrug resistance protein	PA
BC136419.1	Homo sapiens ATP-binding cassette, sub-family C (CFTR/MRP), member 2, mRNA (cDNA clone MGC:168030 IMAGE:9020407), complete cds	P
U49248.1	Human canalicular multispecific organic anion transporter (cMOAT), gene, complete cds	P
U63970.1	Human canalicular multispecific organic anion transporter (cMOAT) mRNA, complete cds	P

EST sequences (10 of 100) [Show all sequences]

AA994962.1	Clone IMAGE:1634957	kidney	3' read	PA
BX116034.1	Clone IMAGp998M17977_;_IMAGE:417592	mixed		P
CB155960.1	Clone L17N670205n1-1-G02	liver	5' read	P
CB120555.1	Clone L8SCK0-16-B02	liver	5' read	P
AI249051.1	Clone IMAGE:1849832	mixed	3' read	P
AI272739.1	Clone IMAGE:1875069	intestine	3' read	A
AI522182.1	Clone IMAGE:2138677	kidney	3' read
AI566147.1	Clone IMAGE:2214030	lung	3' read	P
AI795946.1	Clone IMAGE:2383228	kidney	3' read	A
AI823554.1	Clone IMAGE:2384664	kidney	3' read

Key to Symbols

P Has similarity to known Proteins (after translation)
A Contains a poly-Adenylation signal
S Sequence is a Suboptimal member of this cluster
M Clone is putatively CDS-complete by MGC criteria