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UGID:197405     UniGene Hs.368240     Homo sapiens (human)   DYRK1A Links
Dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 1A (DYRK1A)
SELECTED PROTEIN SIMILARITIES
Comparison of sequences in UniGene with selected protein reference sequences. The alignments can suggest function of a gene.
Reference ProteinSpeciesId(%)Len(aa)
XP_001083622.1 PREDICTED: similar to dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 1A isoform 1 isoform 5 M. mulatta 100.0 762
XP_514894.2 PREDICTED: dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 1A isoform 6 P. troglodytes 100.0 762
NP_001387.2 dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 1A isoform 1 H. sapiens 100.0 762
NP_036923.1 dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 1A R. norvegicus 99.9 762
XP_612233.2 PREDICTED: similar to dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 1A isoform 1 B. taurus 99.9 762
XP_849580.1 PREDICTED: similar to dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 1A isoform 1 isoform 2 C. lupus familiaris 99.8 648
XP_001495397.2 PREDICTED: dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 1A isoform 1 E. caballus 99.8 589
NP_001106860.1 dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 1a M. musculus 99.7 762
NP_001156669.1 dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 1A X. laevis 96.3 749
XP_001923159.1 PREDICTED: similar to mp86 D. rerio 91.1 726
NP_001014750.1 minibrain, isoform G D. melanogaster 85.9 511
NP_510460.2 MiniBrain Kinase (Drosophila) homolog family member (mbk-1) C. elegans 74.3 404
XP_001695011.1 dual-specificity tyrosine regulated protein kinase 1 C. reinhardtii 54.1 318
XP_328578.1 hypothetical protein N. crassa 46.6 579

GENE EXPRESSION
Tissues and development stages from this gene's sequences survey gene expression. Links to other NCBI expression resources.
EST Profile: Approximate expression patterns inferred from EST sources.
[Show more entries with profiles like this]
GEO profiles: Experimental gene expression data (Gene Expression Omnibus).
cDNA Sources: brain; mouth; uncharacterized tissue; lung; placenta; ear; testis; kidney; embryonic tissue; mixed; pituitary gland; uterus; connective tissue; blood; bone marrow; spleen; ovary; lymph; trachea; thymus; eye; intestine; heart; mammary gland; bladder; skin; prostate; thyroid; vascular; muscle; bone; lymph node; stomach; liver; nerve
MAPPING POSITION
Genomic location specified by transcript mapping, radiation hybrid mapping, genetic mapping or cytogenetic mapping.
Chromosome: 21
Map position: 21q22.13
UniSTS entry: Chr 21 RH91183
UniSTS entry: Chr 21 SHGC-52085
UniSTS entry: Chr 21 D21S1972
UniSTS entry: Chr 21 (n/a)
UniSTS entry: (n/a)
UniSTS entry: Chr 21 (n/a)
UniSTS entry: Chr 21 D21S394
UniSTS entry: (n/a)
SEQUENCES
Sequences representing this gene; mRNAs, ESTs, and gene predictions supported by transcribed sequences.

mRNA sequences (20)

BC045802.1 Homo sapiens cDNA clone IMAGE:4816388 A
NM_001396.3 Homo sapiens dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 1A (DYRK1A), transcript variant 1, mRNA P
BC065184.1 Homo sapiens cDNA clone IMAGE:5020947, partial cds A
AF108830.1 Homo sapiens serine-threonine protein kinase (MNBH) mRNA, complete cds P
U58496.1 Human mnb protein kinase homolog hp86 (DYRK) mRNA, complete cds P
NM_130438.2 Homo sapiens dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 1A (DYRK1A), transcript variant 5, mRNA P
NM_130437.2 Homo sapiens dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 1A (DYRK1A), transcript variant 4, mRNA P
NM_130436.2 Homo sapiens dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 1A (DYRK1A), transcript variant 2, mRNA P
NM_101395.2 Homo sapiens dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 1A (DYRK1A), transcript variant 3, mRNA P
AK301752.1 Homo sapiens cDNA FLJ54921 complete cds, highly similar to Dual specific itytyrosine-phosphorylation-regulated kinase 1A (EC 2.7.12.1) P
D85759.1 Homo sapiens mRNA for MNB protein kinase, complete cds P
BC030515.1 Homo sapiens dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 1A, mRNA (cDNA clone IMAGE:5000692), with apparent retained intron A
AB015283.1 Homo sapiens mRNA for MNB/DYRK protein kinase, partial cds, alternatively spliced transcript MNBEX134 P
AB015282.1 Homo sapiens mRNA for MNB/DYRK protein kinase, partial cds, alternatively spliced transcript MNB31 P
AB015284.1 Homo sapiens mRNA for MNB/DYRK protein kinase, partial cds, alternatively spliced transcript MNBEX1-4 P
AJ001871.1 Homo Sapiens mRNA, partial cDNA sequence for human mnb protein kinase homolog, DCR1-14.0, P
AJ001870.1 Homo Sapiens mRNA, partial cDNA sequence for human mnb protein kinase homolog, DCR1-14.0, P
Z25423.1 H.sapiens protein-serine/threonine kinase gene, complete CDS P
U52373.1 Human serine/threonine kinase MNB (mnb) mRNA, complete cds P
D86550.1 Homo sapiens mRNA for serine/threonine protein kinase, complete cds P

EST sequences (10 of 322) [Show all sequences]

AA989240.1 Clone IMAGE:1601875 lung 3' read
AA887600.1 Clone IMAGE:1502062 kidney 3' read
AI002418.1 Clone IMAGE:1601965 lung 3' read
AI002722.1 Clone IMAGE:1683734 brain 3' read P
AA928030.1 Clone IMAGE:1541965 mixed 3' read
R20291.1 Clone IMAGE:32712 brain 5' read
AI076027.1 Clone IMAGE:1670206 brain 3' read A
AI093029.1 Clone IMAGE:1692828 heart 3' read
AI128885.1 Clone IMAGE:1750247 brain 3' read
AI149106.1 Clone IMAGE:1721048 uterus 3' read


Key to Symbols

P Has similarity to known Proteins (after translation)
A Contains a poly-Adenylation signal
S Sequence is a Suboptimal member of this cluster
M Clone is putatively CDS-complete by MGC criteria

 
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