> Ataxia telangiectasia mutated (ATM)
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UGID:197106     UniGene Hs.367437     Homo sapiens (human)   ATM Links
Ataxia telangiectasia mutated (ATM)

Human protein-coding gene ATM. Represented by 293 ESTs from 148 cDNA libraries. Corresponds to reference sequence NM_000051.3. [UniGene 197106 - Hs.367437]

SELECTED PROTEIN SIMILARITIES
Comparison of cluster transcripts with RefSeq proteins. The alignments can suggest function of the cluster.
Best Hits and Hits from model organismsSpeciesId(%)Len(aa)
NP_000042.3 ATM gene product H. sapiens 100.0 3055
NP_031525.2 Atm gene product M. musculus 87.4 3065
NP_001081968.1 ataxia telangiectasia mutated X. laevis 71.3 3060
XP_002664603.2 PREDICTED: serine-protein kinase ATM, partial D. rerio 64.2 2447
NP_190402.6 serine/threonine-protein kinase A. thaliana 60.9 383
NP_001036712.1 telomere fusion D. melanogaster 56.5 377
XP_957745.2 hypothetical protein NCU00274 N. crassa 50.2 257
NP_009465.2 Tel1p S. cerevisiae 47.5 202
Other hits (2 of 54) [Show all]SpeciesId(%)Len(aa)
XP_001139405.2 PREDICTED: serine-protein kinase ATM isoform 4 P. troglodytes 99.2 3018
XP_002799825.1 PREDICTED: serine-protein kinase ATM-like M. mulatta 98.6 2950

GENE EXPRESSION
Tissues and development stages from this gene's sequences survey gene expression. Links to other NCBI expression resources.
EST Profile: Approximate expression patterns inferred from EST sources.
[Show more entries with profiles like this]
GEO Profiles: Experimental gene expression data (Gene Expression Omnibus).
cDNA Sources: brain; mixed; embryonic tissue; eye; lymph node; intestine; thyroid; mammary gland; amniotic fluid; uncharacterized tissue; pharynx; placenta; uterus; lung; muscle; testis; kidney; pancreas; liver; prostate; vascular; connective tissue; adrenal gland; bone marrow; mouth; blood; stomach; spleen; thymus; esophagus; heart; trachea; bladder; nerve; ganglia; skin; parathyroid
MAPPING POSITION
Genomic location specified by transcript mapping, radiation hybrid mapping, genetic mapping or cytogenetic mapping.
Chromosome: 11
Map position: 11q22-q23
UniSTS entry: Chr 11 G54153
UniSTS entry: Chr 11 STS-AA016254 [Map Viewer]
UniSTS entry: Chr 11 G67879
UniSTS entry: Chr 11 SHGC-35479 [Map Viewer]
UniSTS entry: Chr 1 D10S16
UniSTS entry: Chr 11 ATM_exon65c
UniSTS entry: Chr 1 D11S2921
UniSTS entry: Chr 11 ATM_exon65F
UniSTS entry: Chr 11 ATM_exon65a
UniSTS entry: Chr 11 ATM_exon65b
SEQUENCES
Sequences representing this gene; mRNAs, ESTs, and gene predictions supported by transcribed sequences.

mRNA sequences (19)

BT006764.1 Homo sapiens ataxia telangiectasia mutated (includes complementation groups A, C and D) mRNA, complete cds P
BX640631.1 Homo sapiens mRNA; cDNA DKFZp686F08244 (from clone DKFZp686F08244) A
NM_000051.3 Homo sapiens ataxia telangiectasia mutated (ATM), mRNA P
BC061584.1 Homo sapiens ataxia telangiectasia mutated, mRNA (cDNA clone IMAGE:6194499), complete cds PA
CR749436.1 Homo sapiens mRNA; cDNA DKFZp781A0353 (from clone DKFZp781A0353) PA
BC007023.2 Homo sapiens ataxia telangiectasia mutated (includes complementation groups A, C and D), mRNA (cDNA clone IMAGE:3950747) PA
BC152389.1 Homo sapiens ataxia telangiectasia mutated, mRNA (cDNA clone IMAGE:100013451), partial cds P
BC152385.1 Homo sapiens ataxia telangiectasia mutated, mRNA (cDNA clone IMAGE:100013445), complete cds P
AF035328.1 Homo sapiens clone E21ACOR ATM (ATM) mRNA, partial cds
AF035327.1 Homo sapiens clone E15LAR ATM (ATM) mRNA, partial cds
AK093586.1 Homo sapiens cDNA FLJ36267 fis, clone THYMU2002950
AK299843.1 Homo sapiens cDNA FLJ57034 complete cds, highly similar to Serine-protein kinase ATM (EC 2.7.11.1) P
AF035326.1 Homo sapiens clone E15ACOR ATM (ATM) mRNA, partial cds P
BC022306.1 Homo sapiens cDNA clone IMAGE:4770509 A
Y08455.1 H.sapiens mRNA for ataxia telangiectasia protein, exon skipped allele P
X91196.1 H.sapiens mRNA for E14 and A-T proteins P
U33841.1 Human ataxia telangiectasia (ATM) mRNA, complete cds P
HM437232.1 Homo sapiens ATM variant (ATM) mRNA, partial cds P
U67093.1 Human ataxia-telangiectasia locus protein (ATM) mRNA, 3'UTR sequence

EST sequences (10 of 293) [Show all sequences]

AA962359.1 Clone IMAGE:1580069 mixed 3' read
AI148520.1 Clone IMAGE:1714196 placenta 3' read A
AI150723.1 Clone IMAGE:1708402 heart 3' read A
BX096702.1 Clone IMAGp998C10350_;_IMAGE:186945 mammary gland P
AI167315.1 Clone IMAGE:1661218 mixed 3' read P
R26019.1 Clone IMAGE:132664 placenta 5' read
R26821.1 Clone IMAGE:132664 placenta 3' read A
AI262879.1 Clone IMAGE:1868266 kidney 3' read A
CB148120.1 Clone L16HLK3-2-B12 liver 5' read
AI269311.1 Clone IMAGE:1864692 kidney 3' read A


Key to Symbols

P Has similarity to known Proteins (after translation)
A Contains a poly-Adenylation signal
S Sequence is a Suboptimal member of this cluster
M Clone is putatively CDS-complete by MGC criteria

 
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