NCBI UniGene banner graphic
PubMed Nucleotide Protein Genome Structure Popset Taxonomy
 Search
NCBI

UniGene
Homepage
FAQs
Help
Query Tips
Build Info
Library Browser
DDD
Download UniGene

Related Databases
Gene
HomoloGene
EST
SRA

NIH cDNA Projects
Finding cDNAs

UGID:196760     UniGene Hs.364941     Homo sapiens (human)   HSD3B1
Hydroxy-delta-5-steroid dehydrogenase, 3 beta- and steroid delta-isomerase 1 (HSD3B1)

Human protein-coding gene HSD3B1. Represented by 280 ESTs from 59 cDNA libraries. EST representation biased toward placenta; adult. Corresponds to reference sequence NM_000862.2. [UniGene 196760 - Hs.364941]

SELECTED PROTEIN SIMILARITIES
Comparison of cluster transcripts with RefSeq proteins. The alignments can suggest function of the cluster.
Best Hits and Hits from model organismsSpeciesId(%)Len(aa)
NP_000853.1 HSD3B1 gene product H. sapiens 100.0 372
NP_032319.1 Hsd3b1 gene product M. musculus 74.3 372
NP_001089754.1 hydroxy-delta-5-steroid dehydrogenase, 3 beta- and steroid delta-isomerase 1 X. laevis 52.8 376
XP_694204.3 PREDICTED: 3 beta-hydroxysteroid dehydrogenase/Delta 5-->4-isomerase D. rerio 50.8 373
Other hits (2 of 20) [Show all]SpeciesId(%)Len(aa)
XP_001141854.1 PREDICTED: 3 beta-hydroxysteroid dehydrogenase/Delta 5-->4-isomerase type 1 isoform 4 P. troglodytes 99.2 374
XP_003892539.1 PREDICTED: 3 beta-hydroxysteroid dehydrogenase/Delta 5-->4-isomerase type 1-like P. anubis 96.0 372

GENE EXPRESSION
Tissues and development stages from this gene's sequences survey gene expression. Links to other NCBI expression resources.
Restricted Expression: placenta [show more like this]
adult [show more like this]
EST Profile: Approximate expression patterns inferred from EST sources.
[Show more entries with profiles like this]
GEO Profiles: Experimental gene expression data (Gene Expression Omnibus).
cDNA Sources: placenta; mixed; skin; intestine; testis; uncharacterized tissue; uterus; blood; eye; heart; embryonic tissue
MAPPING POSITION
Genomic location specified by transcript mapping, radiation hybrid mapping, genetic mapping or cytogenetic mapping.
Chromosome: 1
Map position: 1p13.1
UniSTS entry: Chr 1 D1S3292 [Map Viewer]
UniSTS entry: Chr 1 HSD3B
UniSTS entry: Chr 1 SHGC-75404 [Map Viewer]
UniSTS entry: Chr 1 RH28
UniSTS entry: Chr 1 HSD3B1
UniSTS entry: Chr 1 D1S2396 [Map Viewer]
UniSTS entry: Chr 1 GDB:182602
SEQUENCES
Sequences representing this gene; mRNAs, ESTs, and gene predictions supported by transcribed sequences.

mRNA sequences (8)

M27137.1 Human 3 beta-hydroxy-5-ene steroid dehydrogenase mRNA, complete cds P
NM_000862.2 Homo sapiens hydroxy-delta-5-steroid dehydrogenase, 3 beta- and steroid delta-isomerase 1 (HSD3B1), mRNA P
M35493.1 Human placental 3-beta-hydroxysteroid dehydrogenase/5-4-isomerase mRNA, complete cds P
X55997.1 Human gene for 3-beta-5-hydroxy-5-ene steroid dehydrogenase P
AK291556.1 Homo sapiens cDNA FLJ75712 complete cds, highly similar to Homo sapiens hydroxy-delta-5-steroid dehydrogenase, 3 beta- and steroid delta-isomerase 1 (HSD3B1), mRNA P
X53321.1 H.sapiens mRNA for 3Beta-hydroxysteroid dehydrogenase/ Delta(5)-> (4)isomerase PA
BC031999.1 Homo sapiens hydroxy-delta-5-steroid dehydrogenase, 3 beta- and steroid delta-isomerase 1, mRNA (cDNA clone MGC:21365 IMAGE:4755300), complete cds PA
S45679.1 3 beta-hydroxysteroid dehydrogenase/delta 5-delta 4 isomerase [human, skin, mRNA, 1665 nt] P

EST sequences (10 of 280) [Show all sequences]

AI075317.1 Clone IMAGE:1672964 mixed 3' read A
R23271.1 Clone IMAGE:131454 placenta 3' read
R23361.1 Clone IMAGE:131454 placenta 5' read
R23831.1 Clone IMAGE:132950 placenta 5' read P
BX094604.1 Clone IMAGp998K241167_;_IMAGE:490511 uterus P
BX114554.1 Clone IMAGp998H231063_;_IMAGE:450502 mixed
R26245.1 Clone IMAGE:133121 placenta 5' read
R27288.1 Clone IMAGE:133503 placenta 5' read
AI221565.1 Clone IMAGE:1759603 placenta 3' read P
R27481.1 Clone IMAGE:133503 placenta 3' read


Key to Symbols

P Has similarity to known Proteins (after translation)
A Contains a poly-Adenylation signal
S Sequence is a Suboptimal member of this cluster
M Clone is putatively CDS-complete by MGC criteria

 
NLM | NIH | UniGene | Privacy Statement | Disclaimer | NCBI Help