> Hydroxy-delta-5-steroid dehydrogenase, 3 beta- and steroid delta-isomerase 1 (HSD3B1)
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UGID:196760     UniGene Hs.364941     Homo sapiens (human)   HSD3B1 Order cDNA clone, Links
Hydroxy-delta-5-steroid dehydrogenase, 3 beta- and steroid delta-isomerase 1 (HSD3B1)

Human protein-coding gene HSD3B1. Represented by 280 ESTs from 59 cDNA libraries. EST representation biased toward placenta; adult. Corresponds to reference sequence NM_000862.2. [UniGene 196760 - Hs.364941]

SELECTED PROTEIN SIMILARITIES
Comparison of cluster transcripts with RefSeq proteins. The alignments can suggest function of the cluster.
Best Hits and Hits from model organismsSpeciesId(%)Len(aa)
NP_000853.1 HSD3B1 gene product H. sapiens 100.0 372
NP_032319.1 Hsd3b1 gene product M. musculus 74.3 372
NP_001089754.1 hydroxy-delta-5-steroid dehydrogenase, 3 beta- and steroid delta-isomerase 1 X. laevis 52.8 376
XP_694204.3 PREDICTED: 3 beta-hydroxysteroid dehydrogenase/Delta 5-->4-isomerase D. rerio 50.8 373
Other hits (2 of 20) [Show all]SpeciesId(%)Len(aa)
XP_001141854.1 PREDICTED: 3 beta-hydroxysteroid dehydrogenase/Delta 5-->4-isomerase type 1 isoform 4 P. troglodytes 99.2 374
XP_003892539.1 PREDICTED: 3 beta-hydroxysteroid dehydrogenase/Delta 5-->4-isomerase type 1-like P. anubis 96.0 372

GENE EXPRESSION
Tissues and development stages from this gene's sequences survey gene expression. Links to other NCBI expression resources.
Restricted Expression: placenta [show more like this]
adult [show more like this]
EST Profile: Approximate expression patterns inferred from EST sources.
[Show more entries with profiles like this]
GEO Profiles: Experimental gene expression data (Gene Expression Omnibus).
cDNA Sources: placenta; mixed; skin; intestine; testis; uncharacterized tissue; uterus; blood; eye; heart; embryonic tissue
MAPPING POSITION
Genomic location specified by transcript mapping, radiation hybrid mapping, genetic mapping or cytogenetic mapping.
Chromosome: 1
Map position: 1p13.1
UniSTS entry: Chr 1 D1S3292 [Map Viewer]
UniSTS entry: Chr 1 HSD3B
UniSTS entry: Chr 1 SHGC-75404 [Map Viewer]
UniSTS entry: Chr 1 RH28
UniSTS entry: Chr 1 HSD3B1
UniSTS entry: Chr 1 D1S2396 [Map Viewer]
UniSTS entry: Chr 1 GDB:182602
SEQUENCES
Sequences representing this gene; mRNAs, ESTs, and gene predictions supported by transcribed sequences.

mRNA sequences (8)

M27137.1 Human 3 beta-hydroxy-5-ene steroid dehydrogenase mRNA, complete cds P
NM_000862.2 Homo sapiens hydroxy-delta-5-steroid dehydrogenase, 3 beta- and steroid delta-isomerase 1 (HSD3B1), mRNA P
M35493.1 Human placental 3-beta-hydroxysteroid dehydrogenase/5-4-isomerase mRNA, complete cds P
X55997.1 Human gene for 3-beta-5-hydroxy-5-ene steroid dehydrogenase P
AK291556.1 Homo sapiens cDNA FLJ75712 complete cds, highly similar to Homo sapiens hydroxy-delta-5-steroid dehydrogenase, 3 beta- and steroid delta-isomerase 1 (HSD3B1), mRNA P
X53321.1 H.sapiens mRNA for 3Beta-hydroxysteroid dehydrogenase/ Delta(5)-> (4)isomerase PA
BC031999.1 Homo sapiens hydroxy-delta-5-steroid dehydrogenase, 3 beta- and steroid delta-isomerase 1, mRNA (cDNA clone MGC:21365 IMAGE:4755300), complete cds PA
S45679.1 3 beta-hydroxysteroid dehydrogenase/delta 5-delta 4 isomerase [human, skin, mRNA, 1665 nt] P

EST sequences (10 of 280) [Show all sequences]

AI075317.1 Clone IMAGE:1672964 mixed 3' read A
R23271.1 Clone IMAGE:131454 placenta 3' read
R23361.1 Clone IMAGE:131454 placenta 5' read
R23831.1 Clone IMAGE:132950 placenta 5' read P
BX094604.1 Clone IMAGp998K241167_;_IMAGE:490511 uterus P
BX114554.1 Clone IMAGp998H231063_;_IMAGE:450502 mixed
R26245.1 Clone IMAGE:133121 placenta 5' read
R27288.1 Clone IMAGE:133503 placenta 5' read
AI221565.1 Clone IMAGE:1759603 placenta 3' read P
R27481.1 Clone IMAGE:133503 placenta 3' read


Key to Symbols

P Has similarity to known Proteins (after translation)
A Contains a poly-Adenylation signal
S Sequence is a Suboptimal member of this cluster
M Clone is putatively CDS-complete by MGC criteria

 
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