> Mannosidase, alpha, class 2B, member 1 (MAN2B1)
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UGID:195599     UniGene Hs.356769     Homo sapiens (human)   MAN2B1 Order cDNA clone, Links
Mannosidase, alpha, class 2B, member 1 (MAN2B1)

Human protein-coding gene MAN2B1. Represented by 1276 ESTs from 282 cDNA libraries. Corresponds to 2 reference sequences (different isoforms). [UniGene 195599 - Hs.356769]

SELECTED PROTEIN SIMILARITIES
Comparison of cluster transcripts with RefSeq proteins. The alignments can suggest function of the cluster.
Best Hits and Hits from model organismsSpeciesId(%)Len(aa)
NP_000519.2 MAN2B1 gene product H. sapiens 100.0 1010
NP_034894.2 Man2b1 gene product M. musculus 85.0 1009
NP_001085364.1 MGC82186 protein X. laevis 75.3 96
NP_001014354.1 man2b1 gene product D. rerio 68.7 976
NP_609408.1 lysosomal alpha-mannosidase, isoform A D. melanogaster 55.3 970
NP_001118706.1 alpha-mannosidase A. thaliana 52.1 839
NP_508811.1 Protein AMAN-1 C. elegans 50.8 463
Other hits (2 of 52) [Show all]SpeciesId(%)Len(aa)
XP_003316198.2 PREDICTED: lysosomal alpha-mannosidase P. troglodytes 98.9 703
XP_003915029.1 PREDICTED: lysosomal alpha-mannosidase P. anubis 98.8 1011

GENE EXPRESSION
Tissues and development stages from this gene's sequences survey gene expression. Links to other NCBI expression resources.
EST Profile: Approximate expression patterns inferred from EST sources.
[Show more entries with profiles like this]
GEO Profiles: Experimental gene expression data (Gene Expression Omnibus).
cDNA Sources: brain; testis; connective tissue; thymus; placenta; lung; uncharacterized tissue; spleen; mouth; trachea; skin; blood; intestine; adipose tissue; embryonic tissue; uterus; cervix; liver; stomach; bone marrow; pancreas; ovary; prostate; kidney; vascular; mixed; mammary gland; eye; thyroid; lymph node; tonsil; lymph; adrenal gland; heart; esophagus; bladder; muscle; pharynx; ascites; bone
MAPPING POSITION
Genomic location specified by transcript mapping, radiation hybrid mapping, genetic mapping or cytogenetic mapping.
Chromosome: 19
Map position: 19cen-q13.1
UniSTS entry: Chr 19 GDB:335318
UniSTS entry: Chr 19 NIB1927 [Map Viewer]
UniSTS entry: Chr 15 Rnu2
SEQUENCES
Sequences representing this gene; mRNAs, ESTs, and gene predictions supported by transcribed sequences.

mRNA sequences (8)

AB209921.1 Homo sapiens mRNA for mannosidase, alpha, class 2B, member 1 precursor variant protein P
NM_000528.3 Homo sapiens mannosidase, alpha, class 2B, member 1 (MAN2B1), transcript variant 1, mRNA PA
BC000736.2 Homo sapiens mannosidase, alpha, class 2B, member 1, mRNA (cDNA clone MGC:2113 IMAGE:3504417), complete cds PA
AK291572.1 Homo sapiens cDNA FLJ76867 complete cds, highly similar to Homo sapiens mannosidase, alpha, class 2B, member 1 (MAN2B1), mRNA PA
U05572.1 Human lysosomal alpha-mannosidase (MANB) mRNA, complete cds PA
U68567.1 Human lysosomal acid alpha-mannosidase mRNA, complete cds P
NM_001173498.1 Homo sapiens mannosidase, alpha, class 2B, member 1 (MAN2B1), transcript variant 2, mRNA PA
U60266.1 Homo sapiens lysosomal alpha-mannosidase (manB) mRNA, complete cds PA

EST sequences (10 of 1276) [Show all sequences]

AA866069.1 Clone IMAGE:1459462 kidney 3' read PA
AA983835.1 Clone IMAGE:1581421 mixed 3' read PA
AI052278.1 Clone IMAGE:1670061 brain 3' read A
AI074441.1 Clone IMAGE:1679247 skin 3' read PA
BX103124.1 Clone IMAGp998P032000_;_IMAGE:810482 ovary
CB164229.1 Clone L17N670205n1-29-B01 liver 5' read P
CB123011.1 Clone L7N800102-12-F12 liver 5' read P
CB147212.1 Clone L7N800102-17-A05 liver 5' read P
CB127163.1 Clone C1SNU17-17-B03 cervix 5' read P
CB122865.1 Clone L10ChoCK0-22-H12 liver 5' read P


Key to Symbols

P Has similarity to known Proteins (after translation)
A Contains a poly-Adenylation signal
S Sequence is a Suboptimal member of this cluster
M Clone is putatively CDS-complete by MGC criteria

 
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