> Peptidylprolyl isomerase A (cyclophilin A) (PPIA)
NCBI UniGene banner graphic
PubMed Nucleotide Protein Genome Structure Popset Taxonomy
 Search
NCBI

UniGene
Homepage
FAQs
Help
Query Tips
Build Info
Library Browser
DDD
Download UniGene

Related Databases
Gene
HomoloGene
EST
SRA

NIH cDNA Projects
MGC | ZGC | XGC
Finding cDNAs
UGID:195429     UniGene Hs.356331     Homo sapiens (human)   PPIA Order cDNA clone, Links
Peptidylprolyl isomerase A (cyclophilin A) (PPIA)

Human protein-coding gene PPIA. Represented by 4641 ESTs from 705 cDNA libraries. Corresponds to reference sequence NM_021130.3. [UniGene 195429 - Hs.356331]

SELECTED PROTEIN SIMILARITIES
Comparison of cluster transcripts with RefSeq proteins. The alignments can suggest function of the cluster.
Best Hits and Hits from model organismsSpeciesId(%)Len(aa)
XP_003895648.1 PREDICTED: peptidyl-prolyl cis-trans isomerase A-like P. anubis 100.0 164
NP_066953.1 PPIA gene product H. sapiens 100.0 164
NP_999518.1 PPIA gene product S. scrofa 100.0 163
NP_032933.1 peptidyl-prolyl cis-trans isomerase A M. musculus 99.4 163
NP_001080260.1 CYcloPhilin (18.4 kD) (cyp-7) X. laevis 87.8 163
NP_956251.1 ppiab gene product D. rerio 85.4 163
NP_729966.1 CG7768 D. melanogaster 81.1 163
NP_195213.1 Peptidyl-prolyl cis-trans isomerase CYP18-4 A. thaliana 79.7 171
XP_001700372.1 peptidyl-prolyl cis-trans isomerase, cyclophilin-type C. reinhardtii 79.0 171
NP_506561.1 Protein CYN-1 C. elegans 78.5 190
NP_010439.1 peptidylprolyl isomerase CPR1 S. cerevisiae 76.4 160
XP_965017.1 hypothetical protein NCU02614 N. crassa 68.7 181
Other hits (2 of 66) [Show all]SpeciesId(%)Len(aa)
XP_507684.3 PREDICTED: peptidyl-prolyl cis-trans isomerase A-like, partial P. troglodytes 99.5 186
XP_002728136.1 PREDICTED: TRIMCyp-like R. norvegicus 99.4 163

GENE EXPRESSION
Tissues and development stages from this gene's sequences survey gene expression. Links to other NCBI expression resources.
EST Profile: Approximate expression patterns inferred from EST sources.
[Show more entries with profiles like this]
GEO Profiles: Experimental gene expression data (Gene Expression Omnibus).
cDNA Sources: brain; lung; skin; pancreas; uncharacterized tissue; liver; uterus; intestine; testis; prostate; embryonic tissue; mixed; eye; mammary gland; placenta; kidney; stomach; lymph; ovary; ascites; blood; lymph node; muscle; thymus; bone; cervix; heart; umbilical cord; adrenal gland; tonsil; bone marrow; bladder; salivary gland; mouth; spleen; vascular; connective tissue; thyroid; pharynx; ear; pituitary gland; adipose tissue; amniotic fluid; larynx; nerve; trachea; esophagus; pineal gland; parathyroid; epididymis; ganglia
MAPPING POSITION
Genomic location specified by transcript mapping, radiation hybrid mapping, genetic mapping or cytogenetic mapping.
Chromosome: 7
Map position: 7p13
UniSTS entry: Chr 11 PMC307696P1
UniSTS entry: Chr 1 PMC262691P6
UniSTS entry: Chr 1 Ppi-rs
UniSTS entry: Chr 11 PMC112625P1
UniSTS entry: Chr 7 G20876
UniSTS entry: Chr 7 A006J31
UniSTS entry: Chr 7 SHGC-56052 [Map Viewer]
UniSTS entry: Chr 7 PPIA
UniSTS entry: RH125522
UniSTS entry: Ppia
SEQUENCES
Sequences representing this gene; mRNAs, ESTs, and gene predictions supported by transcribed sequences.

mRNA sequences (24)

AK130101.1 Homo sapiens cDNA FLJ26591 fis, clone LNF08046, highly similar to Peptidyl-prolyl cis-trans isomerase A (EC 5.2.1.8) P
CR456707.1 Homo sapiens full open reading frame cDNA clone RZPDo834F113D for gene PPIA, peptidylprolyl isomerase A (cyclophilin A); complete cds, incl. stopcodon P
BC073992.1 Homo sapiens peptidylprolyl isomerase A (cyclophilin A), mRNA (cDNA clone MGC:87929 IMAGE:6161389), complete cds PA
BC093076.1 Homo sapiens peptidylprolyl isomerase A (cyclophilin A), mRNA (cDNA clone MGC:111221 IMAGE:30414589), complete cds PA
BC106030.1 Homo sapiens peptidylprolyl isomerase A (cyclophilin A), mRNA (cDNA clone MGC:117158 IMAGE:2986147), complete cds PA
NM_021130.3 Homo sapiens peptidylprolyl isomerase A (cyclophilin A) (PPIA), mRNA P
BC003026.1 Homo sapiens peptidylprolyl isomerase A (cyclophilin A), mRNA (cDNA clone MGC:4203 IMAGE:2823490), complete cds PA
BC000689.2 Homo sapiens peptidylprolyl isomerase A (cyclophilin A), mRNA (cDNA clone MGC:2351 IMAGE:3349335), complete cds PA
BC005320.1 Homo sapiens peptidylprolyl isomerase A (cyclophilin A), mRNA (cDNA clone MGC:12404 IMAGE:3935025), complete cds PA
BC005982.1 Homo sapiens peptidylprolyl isomerase A (cyclophilin A), mRNA (cDNA clone MGC:14681 IMAGE:4109260), complete cds PA
BC007104.1 Homo sapiens peptidylprolyl isomerase A (cyclophilin A), mRNA (cDNA clone MGC:14747 IMAGE:4281376), complete cds PA
BC013915.1 Homo sapiens peptidylprolyl isomerase A (cyclophilin A), mRNA (cDNA clone MGC:22814 IMAGE:3684721), complete cds PA
AK290085.1 Homo sapiens cDNA FLJ78336 complete cds, highly similar to Homo sapiens peptidylprolyl isomerase A (cyclophilin A) (PPIA), transcript variant 1, mRNA P
AK293003.1 Homo sapiens cDNA FLJ75025 complete cds, highly similar to Homo sapiens peptidylprolyl isomerase A (cyclophilin A) (PPIA), transcript variant 2, mRNA PA
AK290851.1 Homo sapiens cDNA FLJ78589 complete cds, highly similar to Homo sapiens peptidylprolyl isomerase A (cyclophilin A) (PPIA), transcript variant 1, mRNA P
AK316564.1 Homo sapiens cDNA, FLJ92934, highly similar to Homo sapiens peptidylprolyl isomerase A (cyclophilin A) (PPIA),mRNA P
Y00052.1 Human mRNA for T-cell cyclophilin P
AK297340.1 Homo sapiens cDNA FLJ53060 complete cds, moderately similar to Peptidyl-prolyl cis-trans isomerase A (EC 5.2.1.8) P
AB451438.1 Homo sapiens PPIA mRNA for peptidylprolyl isomerase A, partial cds, clone: FLJ08164AAAF P
AB451307.1 Homo sapiens PPIA mRNA for peptidylprolyl isomerase A, complete cds, clone: FLJ08164AAAN P
BC018843.2 Homo sapiens peptidylprolyl isomerase A (cyclophilin A), mRNA (cDNA clone IMAGE:3139693) PA
AK026569.1 Homo sapiens cDNA: FLJ22916 fis, clone KAT06406, highly similar to HSCYCR Human mRNA for T-cell cyclophilin PA
BC137058.1 Homo sapiens peptidylprolyl isomerase A (cyclophilin A), mRNA (cDNA clone MGC:168678 IMAGE:9021055), complete cds P
BC137057.1 Homo sapiens peptidylprolyl isomerase A (cyclophilin A), mRNA (cDNA clone MGC:168677 IMAGE:9021054), complete cds P

EST sequences (10 of 4641) [Show all sequences]

AA960889.1 Clone IMAGE:1564669 mixed 3' read PA
AA961754.1 Clone IMAGE:1600245 uncharacterized tissue 3' read PA
AA962171.1 Clone IMAGE:1553473 kidney 3' read PA
AA969707.1 Clone IMAGE:1574750 kidney 3' read
AA983428.1 Clone IMAGE:1598809 uncharacterized tissue 3' read PA
AA984844.1 Clone IMAGE:1630713 brain 3' read P
AA984846.1 Clone IMAGE:1630717 brain 3' read P
AA887523.1 Clone IMAGE:1500528 lung 3' read A
AI014484.1 Clone IMAGE:1607279 mammary gland 3' read A
AI015023.1 Clone IMAGE:1618295 testis 3' read A


Key to Symbols

P Has similarity to known Proteins (after translation)
A Contains a poly-Adenylation signal
S Sequence is a Suboptimal member of this cluster
M Clone is putatively CDS-complete by MGC criteria

 
NLM | NIH | UniGene | Privacy Statement | Disclaimer | NCBI Help