> Fibrinogen alpha chain (FGA)
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UGID:194144     UniGene Hs.351593     Homo sapiens (human)   FGA Order cDNA clone, Links
Fibrinogen alpha chain (FGA)

Human protein-coding gene FGA. Represented by 1120 ESTs from 79 cDNA libraries. EST representation biased toward liver. Corresponds to 2 reference sequences (different isoforms). [UniGene 194144 - Hs.351593]

SELECTED PROTEIN SIMILARITIES
Comparison of cluster transcripts with RefSeq proteins. The alignments can suggest function of the cluster.
Best Hits and Hits from model organismsSpeciesId(%)Len(aa)
NP_000499.1 FGA gene product H. sapiens 100.0 865
NP_001104518.1 Fga gene product M. musculus 81.1 788
NP_001080329.1 fibrinogen alpha chain precursor X. laevis 57.5 752
XP_001923586.1 PREDICTED: fibrinogen-like protein 1-like D. rerio 47.6 225
Other hits (2 of 27) [Show all]SpeciesId(%)Len(aa)
XP_001136067.1 PREDICTED: fibrinogen alpha chain isoform 1 P. troglodytes 98.6 865
XP_001088855.2 PREDICTED: fibrinogen alpha chain isoform 1 M. mulatta 95.2 880

GENE EXPRESSION
Tissues and development stages from this gene's sequences survey gene expression. Links to other NCBI expression resources.
Restricted Expression: liver [show more like this]
EST Profile: Approximate expression patterns inferred from EST sources.
[Show more entries with profiles like this]
GEO Profiles: Experimental gene expression data (Gene Expression Omnibus).
cDNA Sources: liver; blood; mixed; uncharacterized tissue; mammary gland; heart; spleen; testis; lung; stomach; kidney; uterus; bladder; muscle; embryonic tissue; brain; placenta; lymph; pancreas; connective tissue
MAPPING POSITION
Genomic location specified by transcript mapping, radiation hybrid mapping, genetic mapping or cytogenetic mapping.
Chromosome: 4
Map position: 4q28
UniSTS entry: Chr 4 SHGC-32984 [Map Viewer]
UniSTS entry: Chr 4 SHGC-59770 [Map Viewer]
UniSTS entry: Chr 4 STS-H58121 [Map Viewer]
UniSTS entry: Chr 4 SHGC-34795 [Map Viewer]
UniSTS entry: Chr 4 SHGC-50337
UniSTS entry: Chr 4 SHGC-59324 [Map Viewer]
UniSTS entry: Chr 4 GDB:187393
UniSTS entry: Chr 4 RH18276 [Map Viewer]
UniSTS entry: Chr 4 STS-H72060 [Map Viewer]
UniSTS entry: G33492
SEQUENCES
Sequences representing this gene; mRNAs, ESTs, and gene predictions supported by transcribed sequences.

mRNA sequences (15)

M58569.1 Homo sapiens fibrinogen alpha subunit and fibrinogen alpha subunit precursor, genes, complete cds P
NM_000508.3 Homo sapiens fibrinogen alpha chain (FGA), transcript variant alpha-E, mRNA P
BC070246.1 Homo sapiens fibrinogen alpha chain, mRNA (cDNA clone IMAGE:4766853), complete cds PA
J00127.1 Human fibrinogen alpha-chain mRNA, complete cds P
J00128.1 Human fibrinogen A-alpha-chain mRNA, complete cds P
M26878.1 Human alpha-fibrinogen mRNA, 3' end
BC098280.1 Homo sapiens fibrinogen alpha chain, mRNA (cDNA clone MGC:119424 IMAGE:40007214), complete cds P
BC099706.1 Homo sapiens fibrinogen alpha chain, transcript variant alpha, mRNA (cDNA clone MGC:119422 IMAGE:40007212), complete cds P
BC099720.1 Homo sapiens fibrinogen alpha chain, mRNA (cDNA clone MGC:119425 IMAGE:40007215), complete cds P
BC101935.1 Homo sapiens fibrinogen alpha chain, mRNA (cDNA clone MGC:119423 IMAGE:40007213), complete cds P
BC105803.1 Homo sapiens fibrinogen alpha chain, mRNA (cDNA clone IMAGE:4711814), partial cds PA
NM_021871.2 Homo sapiens fibrinogen alpha chain (FGA), transcript variant alpha, mRNA P
BC020764.1 Homo sapiens fibrinogen alpha chain, mRNA (cDNA clone IMAGE:4767540), complete cds PA
AK290559.1 Homo sapiens cDNA FLJ78367 complete cds, highly similar to Homo sapiens fibrinogen, A alpha polypeptide (FGA), transcriptvariant alpha, mRNA PA
K02272.1 Human fibrinogen A-alpha-chain mRNA fragment

EST sequences (10 of 1120) [Show all sequences]

AA865707.1 Clone IMAGE:1469138 uncharacterized tissue 3' read PA
AI130813.1 Clone IMAGE:1709123 heart 3' read PA
AI150074.1 Clone IMAGE:1752372 testis 3' read A
CB149007.1 Clone L17N670205-1-H12 liver 5' read P
CB153830.1 Clone L17N670205-7-C02 liver 5' read P
CB153846.1 Clone L17N670205-7-E08 liver 5' read P
CB154122.1 Clone L17N670205-3-F09 liver 5' read P
CB154127.1 Clone L17N670205-3-G06 liver 5' read P
CB154138.1 Clone L17N670205-3-H11 liver 5' read P
CB154233.1 Clone L17N670205-5-E12 liver 5' read P


Key to Symbols

P Has similarity to known Proteins (after translation)
A Contains a poly-Adenylation signal
S Sequence is a Suboptimal member of this cluster
M Clone is putatively CDS-complete by MGC criteria

 
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