> Major histocompatibility complex, class II, DM beta (HLA-DMB)
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UGID:194011     UniGene Hs.351279     Homo sapiens (human)   HLA-DMB
Major histocompatibility complex, class II, DM beta (HLA-DMB)

Human protein-coding gene HLA-DMB. Represented by 319 ESTs from 136 cDNA libraries. Corresponds to reference sequence NM_002118.4. [UniGene 194011 - Hs.351279]

SELECTED PROTEIN SIMILARITIES
Comparison of cluster transcripts with RefSeq proteins. The alignments can suggest function of the cluster.
Best Hits and Hits from model organismsSpeciesId(%)Len(aa)
NP_002109.2 HLA-DMB gene product H. sapiens 100.0 262
NP_034518.1 histocompatibility 2, class II, locus Mb2 precursor M. musculus 77.0 260
Other hits (2 of 11) [Show all]SpeciesId(%)Len(aa)
NP_001127814.1 PATR-DMB gene product P. troglodytes 99.2 262
XP_002803734.1 PREDICTED: HLA class II histocompatibility antigen, DM beta chain-like M. mulatta 91.2 262

GENE EXPRESSION
Tissues and development stages from this gene's sequences survey gene expression. Links to other NCBI expression resources.
EST Profile: Approximate expression patterns inferred from EST sources.
[Show more entries with profiles like this]
GEO Profiles: Experimental gene expression data (Gene Expression Omnibus).
cDNA Sources: uncharacterized tissue; pharynx; uterus; lung; brain; spleen; lymph node; placenta; thyroid; heart; kidney; mixed; stomach; spinal cord; blood; adrenal gland; embryonic tissue; bone marrow; prostate; connective tissue; intestine; pancreas; lymph; mammary gland; trachea; thymus; liver; larynx; tonsil; adipose tissue; muscle; testis; eye; skin; ovary; bone; bladder
MAPPING POSITION
Genomic location specified by transcript mapping, radiation hybrid mapping, genetic mapping or cytogenetic mapping.
Chromosome: 6
Map position: 6p21.3
UniSTS entry: Chr 6 RH12803 [Map Viewer]
UniSTS entry: Chr 6 D6S2091 [Map Viewer]
UniSTS entry: Chr 6 SHGC-144492
UniSTS entry: Chr 6 PMC316580P3
SEQUENCES
Sequences representing this gene; mRNAs, ESTs, and gene predictions supported by transcribed sequences.

mRNA sequences (10)

U15085.1 Human HLA-DMB mRNA, complete cds P
NM_002118.4 Homo sapiens major histocompatibility complex, class II, DM beta (HLA-DMB), mRNA P
CR407606.1 Homo sapiens full open reading frame cDNA clone RZPDo834A052D for gene HLA-DMB, major histocompatibility complex, class II, DM beta complete cds, without stopcodon P
AY645722.1 Homo sapiens MHC class II antigen (HLA-DMB) mRNA, complete cds P
AB362556.1 Homo sapiens HLA-DMB mRNA for MHC class II antigen, partial cds, splicing variant 3
AB362555.1 Homo sapiens HLA-DMB mRNA for MHC class II antigen, partial cds, splicing variant 2
AB362554.1 Homo sapiens HLA-DMB mRNA for MHC class II antigen, partial cds, splicing variant 1
BC027175.1 Homo sapiens major histocompatibility complex, class II, DM beta, mRNA (cDNA clone MGC:17194 IMAGE:4341639), complete cds PA
AK301017.1 Homo sapiens cDNA FLJ51332 complete cds, highly similar to HLA class II histocompatibility antigen, DMbeta chain precursor P
Z23139.1 H.sapiens RING7 mRNA for HLA class II alpha chain-like product P

EST sequences (10 of 319) [Show all sequences]

AI082364.1 Clone IMAGE:1670937 uncharacterized tissue 3' read A
R22329.1 Clone IMAGE:130889 placenta 5' read
R22330.1 Clone IMAGE:130889 placenta 3' read
AI151459.1 Clone IMAGE:1715368 placenta 3' read
BX115870.1 Clone IMAGp998J19780_;_IMAGE:341874 heart P
AI269194.1 Clone IMAGE:1864638 kidney 3' read A
AI224475.1 Clone IMAGE:2000549 lymph node 3' read A
AI287991.1 Clone IMAGE:1980795 kidney 3' read A
AI301001.1 Clone IMAGE:1902758 kidney 3' read A
AI357110.1 Clone IMAGE:2001552 lymph node 3' read A


Key to Symbols

P Has similarity to known Proteins (after translation)
A Contains a poly-Adenylation signal
S Sequence is a Suboptimal member of this cluster
M Clone is putatively CDS-complete by MGC criteria

 
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