> Sclerostin (SOST)
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UGID:193702     UniGene Hs.349204     Homo sapiens (human)   SOST Order cDNA clone, Links
Sclerostin (SOST)

Human protein-coding gene SOST. Represented by 19 ESTs from 8 cDNA libraries. EST representation biased toward normal. Corresponds to reference sequence NM_025237.2. [UniGene 193702 - Hs.349204]

SELECTED PROTEIN SIMILARITIES
Comparison of cluster transcripts with RefSeq proteins. The alignments can suggest function of the cluster.
Best Hits and Hits from model organismsSpeciesId(%)Len(aa)
NP_079513.1 SOST gene product H. sapiens 100.0 212
XP_001153653.1 PREDICTED: sclerostin isoform 2 P. troglodytes 99.5 212
NP_077769.3 sclerostin precursor M. musculus 89.6 210
XP_001340683.1 PREDICTED: sclerostin-like D. rerio 55.3 208
Other hits (2 of 16) [Show all]SpeciesId(%)Len(aa)
XP_003913189.1 PREDICTED: sclerostin P. anubis 98.1 212
XP_002800569.1 PREDICTED: sclerostin-like isoform 2 M. mulatta 97.2 216

GENE EXPRESSION
Tissues and development stages from this gene's sequences survey gene expression. Links to other NCBI expression resources.
Restricted Expression: normal [show more like this]
EST Profile: Approximate expression patterns inferred from EST sources.
[Show more entries with profiles like this]
GEO Profiles: Experimental gene expression data (Gene Expression Omnibus).
cDNA Sources: kidney; embryonic tissue; mixed; vascular; bone
MAPPING POSITION
Genomic location specified by transcript mapping, radiation hybrid mapping, genetic mapping or cytogenetic mapping.
Chromosome: 17
Map position: 17q11.2
SEQUENCES
Sequences representing this gene; mRNAs, ESTs, and gene predictions supported by transcribed sequences.

mRNA sequences (11)

AF184211.1 Homo sapiens MST148 protein (MST148) mRNA, complete cds PA
AF170491.1 Homo sapiens MSTP078 (MST078) mRNA, complete cds A
AY358627.1 Homo sapiens clone DNA115253 SOST (UNQ2976) mRNA, complete cds PA
AY358203.1 Homo sapiens clone DNA102863 SOST (UNQ2976) mRNA, complete cds P
BC101088.1 Homo sapiens sclerosteosis, mRNA (cDNA clone MGC:119632 IMAGE:40009485), complete cds P
BC101089.1 Homo sapiens sclerosteosis, mRNA (cDNA clone MGC:119633 IMAGE:40009488), complete cds P
BC101087.1 Homo sapiens sclerosteosis, mRNA (cDNA clone MGC:119631 IMAGE:40009482), complete cds P
BC101086.1 Homo sapiens sclerosteosis, mRNA (cDNA clone MGC:119630 IMAGE:40009481), complete cds P
NM_025237.2 Homo sapiens sclerostin (SOST), mRNA PA
AF331844.1 Homo sapiens SOST (SOST) mRNA, complete cds PA
AF326739.1 Homo sapiens sclerostin mRNA, complete cds PA

EST sequences (10 of 19) [Show all sequences]

AA969408.1 Clone IMAGE:1580533 mixed 3' read
AI383985.1 Clone IMAGE:2088699 mixed 3' read A
AI498457.1 Clone IMAGE:2161468 kidney 3' read A
AI498691.1 Clone IMAGE:2160770 kidney 3' read A
AI493134.1 Clone IMAGE:2030283 kidney 3' read A
AI580267.1 Clone IMAGE:2161096 kidney 3' read A
AI768408.1 Clone IMAGE:2380708 kidney 3' read A
AI783624.1 Clone IMAGE:2296709 kidney 3' read A
BX282099.1 Clone IMAGp998B055912_;_IMAGE:2380708 kidney P
CD250782.1 Clone IMAGE:30382115 vascular 5' read A


Key to Symbols

P Has similarity to known Proteins (after translation)
A Contains a poly-Adenylation signal
S Sequence is a Suboptimal member of this cluster
M Clone is putatively CDS-complete by MGC criteria

 
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